Spectrophotometric Determination of Oxymetazoline Hydrochloride in Pure and Pharmaceutical Preparations Using Diazo-coupling Reaction

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Spectrophotometric Determination of Oxymetazoline Hydrochloride in Pure and Pharmaceutical Preparations Using Diazo-coupling Reaction

Thabit Al-Ghabsha et al · University of Mosul, College of Education for Pure Science · 2019

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Autor / responsable

Thabit Al-Ghabsha et al

Editorial

University of Mosul, College of Education for Pure Science

Año

2019

ISSN

1812-125X

ISSN

1812-125X

Idioma

eng

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A ccurate and simple spectrophotometric method has been suggested for the determination ofoxymetazoline hydrochloride (OMCl) in aqueous solution is developed. The present process included coupling of OMCl with diazotized sulphanilic acid reagent in the presence of sodium hydroxide. The orange colored azo dye formed very stable and soluble in water gives maximum absorption at 496 nm. The lineratey is obeyed over the range 20 – 400 mg / 25 ml (0.8 –16µg.ml-1) the molar absorptivity is equate to 2.30 ´ 104 l.mol-1cm-1. The proposed method has been used to the determination of OMCl in two formulations with satisfactories results.

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APA 7

al, T. A. G. E. (2019). Spectrophotometric Determination of Oxymetazoline Hydrochloride in Pure and Pharmaceutical Preparations Using Diazo-coupling Reaction. https://doi.org/10.33899/edusj.1999.163319

MLA

al, Thabit Al-Ghabsha et. "Spectrophotometric Determination of Oxymetazoline Hydrochloride in Pure and Pharmaceutical Preparations Using Diazo-coupling Reaction." 2019. https://doi.org/10.33899/edusj.1999.163319.

Chicago

al, Thabit Al-Ghabsha et. 2019. "Spectrophotometric Determination of Oxymetazoline Hydrochloride in Pure and Pharmaceutical Preparations Using Diazo-coupling Reaction.". https://doi.org/10.33899/edusj.1999.163319.

Harvard

al, T. A. G. E. 2019, Spectrophotometric Determination of Oxymetazoline Hydrochloride in Pure and Pharmaceutical Preparations Using Diazo-coupling Reaction, University of Mosul, College of Education for Pure Science, available at: https://doi.org/10.33899/edusj.1999.163319 [Accessed 30 Jun. 2026].

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Título: Spectrophotometric Determination of Oxymetazoline Hydrochloride in Pure and Pharmaceutical Preparations Using Diazo-coupling Reaction

Autor / colaboradores: Thabit Al-Ghabsha et al

Editorial: University of Mosul, College of Education for Pure Science

Año de publicación: 2019

ISSN: 1812-125X

ISSN: 1812-125X

Idioma: eng

Materias

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spectrophotometric determination; diazotization; oxymetazoline hydrochloride; sulphanilic acid