The inhibitory effect of extracts of tea plant and tannins isolated from the growth of E. coli pathogen of isolated intestines from infants with diarrhea Enteropathogenic Escherchia coli (EPEC) in Mosul

This study included isolation and diagnosis of the Enteropathogenic Escherchia coli (EPEC)from diarrhoeal cases in infants.Specimens were collected from(243) patients under 2 years during the period July 2002- March 2003. The follwing serotypes were isolated : (EPEC)O126 (47% ), (EPEC) O119 (%26) (EPEC) O111 (%20), and (EPEC) O114(7%) . The results indicated that the aqueous, alcoholic extracts and the Tannins separated from tea have inhibitory effect in all serotypes of EPEC. The study also included determination of the minimum inhibitory concentration (M.I.C) for the aqueous, alcoholic and organic extracts and some of the effective components of the tea . The detection of the inhibitory effect for the separated Tannin in the growth of the EPEC In vivo, using the Illeal rabbit loop test showed that the Tanin has an inhibitory effect in the EPEC through the measurement of the dilatation indicator which was showed to be : (0.38) and in comparison with the other dilatation indicator measurement.