Mithridatism for dementia? Hypoxic - Hyperoxic training in dementia

Introduction: Intense research on dementia has been conducted during the last years. As advances in the field have started changing the landscape of dementia treatment, it is necessary to assess the impact of novel therapeutic modalities. Purpose: The current evidence about hypoxic – hyperoxic treatment for dementia is reviewed in this article. Methods: We conducted a thorough PubMed/MEDLINE and Google Scholar search. Results: Preclinical and clinical data are available. Hypoxic – hyperoxic treatment is encouraged in the context of the multimodal treatment of dementia. There are concerns about the recovery of memory with regard to specific modalities of this treatment. Future perspectives are highlighted in the light of potentially useful biomarkers and health policy. Conclusion: While constant updates and further research is critical to understand the impact of hypoxic – hyperoxic treatment in dementia, the available studies are limited and, hence, research that is more extensive is necessary. Currently, it is important to assess the current state of knowledge highlighting the success but also the stalemates of this treatment