Adiponectin serum levels and their relationships to androgen concentrations and ovarian volume during puberty in girls with type 1 diabetes mellitus

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Adiponectin serum levels and their relationships to androgen concentrations and ovarian volume during puberty in girls with type 1 diabetes mellitus

Iñíguez Vila, Germán et al · Universidad de Chile · 2019

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Autor / responsable

Iñíguez Vila, Germán et al

Editorial

Universidad de Chile

Año

2019

ISSN

03010163

ISSN

03010163

Idioma

Inglés

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Universidad de Chile Universidad de Chile OAI-PMH

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Aim: To study the adiponectin levels during puberty in girls with type 1 diabetes mellitus (DM1) and their relationship to body mass index (BMI), Tanner stage, ovarian volume (OV), and androgen levels. Methods: We studied adiponectin and testosterone levels and OV in 56 pubertal girls with DM1 and in 59 healthy girls serving as controls. The effects of DM1, BMI standard deviation scores (BMI SDS), testosterone, and OV over adiponectin levels were assessed. Results: The adiponectin levels were higher in the DM1 girls as compared with the controls. There was a significant decrease in adiponectin concentrations during puberty in DM1 girls only. The adiponectin levels in the girls with DM1, but not in the controls, exhibited a negative correlation with OV (r = -0.427, p = 0.002) and testosterone (r = -0.262, p = 0.049). Regression analysis showed DM1, BMI SDS, testosterone levels, and OV to be significant factors over adiponectin levels. The effect of Tanner stage was due to differences in

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APA 7

Iñíguez Vila, G. E. A. (2019). Adiponectin serum levels and their relationships to androgen concentrations and ovarian volume during puberty in girls with type 1 diabetes mellitus. https://doi.org/10.1159/000137656

MLA

Iñíguez Vila, Germán et al. "Adiponectin serum levels and their relationships to androgen concentrations and ovarian volume during puberty in girls with type 1 diabetes mellitus." 2019. https://doi.org/10.1159/000137656.

Chicago

Iñíguez Vila, Germán et al. 2019. "Adiponectin serum levels and their relationships to androgen concentrations and ovarian volume during puberty in girls with type 1 diabetes mellitus.". https://doi.org/10.1159/000137656.

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Iñíguez Vila, G. E. A. 2019, Adiponectin serum levels and their relationships to androgen concentrations and ovarian volume during puberty in girls with type 1 diabetes mellitus, Universidad de Chile, available at: https://doi.org/10.1159/000137656 [Accessed 6 Aug. 2026].

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Título: Adiponectin serum levels and their relationships to androgen concentrations and ovarian volume during puberty in girls with type 1 diabetes mellitus

Autor / colaboradores: Iñíguez Vila, Germán et al

Editorial: Universidad de Chile

Año de publicación: 2019

ISSN: 03010163

ISSN: 03010163

Idioma: Inglés

Materias

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Adiponectin; Hyperandrogenism; Puberty; Type 1 diabetes mellitus