Determination of bromide ion in beverage raw water using liquid chromatography/tandem mass spectrometry (LC/MS/MS)

The bromide ion analysis method in beverage raw water by liquid chromatography/tandem mass spectrometry (LC/MS/MS) was examined, and its validity was evaluated by addition recovery test. As a measurement condition, a multimode column reversed phase + anion exchange resins, into which a quaternary ammonium group was introduced, were used for the purpose of appropriately separating for high朴olarity bromide ion and other ionic compounds on the chromatogram. The calibration curve of bromide ion showed good linearity in the concentration range of 0.5 to 10 ｵg/L, and the repeatability (RSD) of the 1.0 ｵg/L bromic acid standard solution was good (2.4 %). Furthermore, as a result of the addition recovery test (n = 7) of ground water, the results for bromide ion in tap water showed that the recovery efficiency was 90 % and the RSD was 1.4 %, and satisfied results were obtained for the real samples.