Buscar recursos académicos

Abstract Summary: MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252 Gbps in 44.1 and 9...

The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagen...

Materias / palabras clave: Offshore assembly industry; Mexican-American Border Region; Women offshore assembly industry workers; Fábrica; Mujer

Materias / palabras clave: Genome; Reference genome; Biology; De novo transcriptome assembly; Computational biology; Sequence assembly; Transcriptome; Massive parallel sequencing; Deep sequencing; Genetics; RNA-Seq; Gene

Materias / palabras clave: Chemistry; Supramolecular chemistry; Nanotechnology; Nanoparticle; Supramolecular catalysis; Colloidal gold; Catalysis; Supramolecular assembly; Self-assembly; Quantum dot; Organic chemistry; Molecule

Advances in modern sequencing technologies allow us to generate sufficient data to analyze hundreds of bacterial genomes from a single machine in a single day. This potential for sequencing massive numbers of genomes cal...

Materias / palabras clave: Biology; RNA-Seq; Gene; RNA splicing; Transcriptome; Computational biology; Alternative splicing; Genetics; Genome; De novo transcriptome assembly; Gene expression; Gene isoform

MOTIVATION: Genomics has revolutionized biological research, but quality assessment of the resulting assembled sequences is complicated and remains mostly limited to technical measures like N50. RESULTS: We propose a mea...

Materias / palabras clave: DNA ligase; DNA; Exonuclease; DNA polymerase; DNA clamp; Ligase chain reaction; Biology; In vitro recombination; Computational biology; Gene; Chemistry; Genetics

MOTIVATION: Next-generation sequencing technologies generate very large numbers of short reads. Even with very deep genome coverage, short read lengths cause problems in de novo assemblies. The use of paired-end librarie...

UNLABELLED: The multiplex capability and high yield of current day DNA-sequencing instruments has made bacterial whole genome sequencing a routine affair. The subsequent de novo assembly of reads into contigs has been we...

SUMMARY: Limitations of genome sequencing techniques have led to dozens of assembly algorithms, none of which is perfect. A number of methods for comparing assemblers have been developed, but none is yet a recognized ben...

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months fr...

The Illumina DNA sequencing platform generates accurate but short reads, which can be used to produce accurate but fragmented genome assemblies. Pacific Biosciences and Oxford Nanopore Technologies DNA sequencing platfor...

Materias / palabras clave: Computational biology; Bioconductor; RNA-Seq; Sequence assembly; Workflow; Transcriptome; Biology; De novo transcriptome assembly; Genome; Reference genome; Computer science; Sequence analysis

Materias / palabras clave: Sequence assembly; De novo transcriptome assembly; Transcriptome; Computational biology; RNA-Seq; Computer science; Set (abstract data type); Biology; Sequence (biology); Software; Gene; Genetics

We use high-resolution N-body simulations to study the equilibrium density profiles of dark matter halos in hierarchically clustering universes. We find that all such profiles have the same shape, independent of halo mas...

To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. Here we describe the Illumina-based metagenomic sequencing, assembly and characterization of 3.3 mi...

Although much biological research depends upon species diagnoses, taxonomic expertise is collapsing. We are convinced that the sole prospect for a sustainable identification capability lies in the construction of systems...

Many potential applications have been proposed for carbon nanotubes, including conductive and high-strength composites; energy storage and energy conversion devices; sensors; field emission displays and radiation sources...

Organized groups of teachers of mathematics or of individuals preparing to become teachers of mathematics may petition the NCTM Board of Directors to become affiliated with the Council. Affiliated Groups are entitled to ...

Background Metal-organic frameworks (MOFs) are made by linking inorganic and organic units by strong bonds (reticular synthesis). The flexibility with which the constituents’ geometry, size, and functionality can be va...