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Materias / palabras clave: Computational biology; Biology; Profiling (computer programming); Phenotype; Transcriptome; Computer science; Genetics; Gene; Gene expression; Operating system

Jacob Devlin, Ming-Wei Chang, Kenton Lee, Kristina Toutanova. Proceedings of the 2019 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies, Volume 1 (Long...

MOTIVATION: Next-generation sequencing technologies generate very large numbers of short reads. Even with very deep genome coverage, short read lengths cause problems in de novo assemblies. The use of paired-end librarie...

The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underlying principles. As knowledge of cancer mechanisms has p...

SUMMARY: It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics applications. One of the fundamental data analysis ta...

Motivation: Recent advances in sequencing technologies promise ultra-long reads of ∼100 kb in average, full-length mRNA or cDNA reads in high throughput and genomic contigs over 100 Mb in length. Existing alignment pro...

Functional elucidation of causal genetic variants and elements requires precise genome editing technologies. The type II prokaryotic CRISPR (clustered regularly interspaced short palindromic repeats)/Cas adaptive immune ...

Advances in modern sequencing technologies allow us to generate sufficient data to analyze hundreds of bacterial genomes from a single machine in a single day. This potential for sequencing massive numbers of genomes cal...

The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagen...

MOTIVATION: Accurate alignment of high-throughput RNA-seq data is a challenging and yet unsolved problem because of the non-contiguous transcript structure, relatively short read lengths and constantly increasing through...

TopHat is a popular spliced aligner for RNA-sequence (RNA-seq) experiments. In this paper, we describe TopHat2, which incorporates many significant enhancements to TopHat. TopHat2 can align reads of various lengths produ...

The Illumina DNA sequencing platform generates accurate but short reads, which can be used to produce accurate but fragmented genome assemblies. Pacific Biosciences and Oxford Nanopore Technologies DNA sequencing platfor...

MOTIVATION: Next-generation sequencing technologies generate millions of short sequence reads, which are usually aligned to a reference genome. In many applications, the key information required for downstream analysis i...

Understanding the evolutionary history of living organisms is a central problem in biology. Until recently the ability to infer evolutionary relationships was limited by the amount of DNA sequence data available, but new...

Materias / palabras clave: computational mathematics, cybernetics, computer science; Science: Mathematics: Instruments and machines: Electronic computers. Computer science

Materias / palabras clave: advanced computing, computational technologies, innovative applications, theoretical advancements, practical implementations, industry applications; Technology: Technology (General); Science: Science (General)

Materias / palabras clave: sequencing technologies, genome editing and genome engineering, imaging technologies, single-molecule methods, computational methods, machine learning; Technology: Chemical technology: Biotechnology; Science: Chemistry: ...

Materias / palabras clave: crop improvement, plant biotechnology, multi-omics technologies, crop protection & abiotic atress, computational biology & artificial intelligence; Agriculture: Agriculture (General); Technology: Chemical technology: Bio...

Materias / palabras clave: antenna theory and practice, electromagnetic compatibility, microwave theory and techniques, computational electromagnetics, photonics, magnetic materials and technologies; Science: Physics: Electricity and magnetism

Materias / palabras clave: computer science, computational mathematics, it education, digital economics, big data and applications, convergent cognitive information technologies; Science: Mathematics: Instruments and machines: Electronic computers...