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ABSTRACT Deep brain stimulation (DBS) for treatment‐resistant depression (TRD) is challenged by significant individual variability in efficacy and unclear neural circuit mechanisms. To address this, a cross‐species, ...

Sharon Wang-Price,1 Jason Zafereo,2 Khalid Alkhathami,3,* Yousef Alshehre,4,* Hui-Ting Goh1 1School of Physical Therapy, College of Health Sciences, Texas Woman’s University, Dallas, TX, USA; 2Departmen...

This review examines the application of brain–computer interface (BCI) technology for motor rehabilitation in patients with severe stroke—a population often excluded from conventional therapies due to minimal movemen...

BackgroundDespite growing evidence supporting deep brain stimulation (DBS) for treatment- resistant depression (TRD), how stimulation delivered across hemispheres or across multiple targets interact to shape large-scale ...

BackgroundAttention deficits often persist after mild traumatic brain injury (mTBI), limiting recovery despite normal imaging. Transcranial direct current stimulation (tDCS) has emerged as a non-invasive therapeutic opti...

Abstract Introduction Non-invasive brain stimulation (NIBS) as monotherapy has been increasingly used to enhance the activity of brain networks. However, it is unclear whether a combination of distinct NIBS approaches ...

Abstract Background Mild cognitive impairment (MCI) is an intermediate stage between normal cognitive aging and dementia. People with MCI have a higher risk of developing dementia than normal healthy people. Improving th...

The purpose of this study is to examine the effects of applying anodal tDCS (2 mA for 20 min) over the scalp from T3 (anodal-tDCS) to Fp2 (cathodal-tDCS) on the perceptual, physiological and performance responses dur...

Abstract Objectives To explore the efficacy and potential neurophysiological mechanisms of 77.5 Hz transcranial alternating current stimulation (tACS) in the treatment of female adolescent non-suicidal self-injury (NSSI...

IntroductionHuman space exploration is progressing into an unprecedented era characterized by extended-duration missions, the establishment of permanent lunar bases, and planned crewed voyages to Mars. These activities i...

Depression represents a significant global public health problem, negatively affecting patients’ quality of life and social functioning. Despite the increasing availability of effective pharmacological and psychotherap...

IntroductionMotor imagery (MI), the mental rehearsal of movement without physical execution, is a key technique in brain-computer interfaces (BCIs), known for eliciting cortical modulations similar to those exhibited dur...

ObjectiveThis study aimed to investigate the effect of high-frequency transcranial magnetic stimulation (TMS) targeting multiple brain regions on the recovery of consciousness in patients with minimally conscious state (...

Brain-computer interface (BCI) is a neuro-engineering technology that establishes a direct communication pathway between the brain and external devices. It can realize bidirectional information interaction between the br...

Background: Approximately 40% of individuals who experience an ankle sprain subsequently develop Chronic Ankle Instability (CAI). Recent evidence highlights alterations in Central Nervous System (CNS) function and defici...

BackgroundDepressive disorders are clinically heterogeneous and mechanistically complex psychiatric conditions. Transcranial direct current stimulation (tDCS), a key non-invasive neuromodulation technique, has expanded r...

ABSTRACT The present study aimed to analyse the wave morphology, amplitude, latency, and intervals of the brainstem auditory evoked responses (BAERs) in dogs with central vestibular syndrome (CVS) recorded with surface e...

Background Acute ischaemic stroke often leads to significant disability and mortality. Secondary brain injury caused by post-stroke immune and inflammatory responses worsens outcomes.Aim To assess the efficacy and safety...

Sham transcranial direct current stimulation (tDCS) is essential for causal inference but is commonly implemented as ramp-only protocols that may not ensure physiological inertness and may fail to maintain mid-session bl...

Abstract Background Cerebellar ataxia (CA) is a neurodegenerative disorder characterized by progressive impairments in coordination, balance, and gait disturbances. Conventional rehabilitation therapies offer only limite...

Resumen: La enfermedad de Alzheimer es actualmente la principal causa de demencia en los adultos mayores. De hecho, esta enfermedad neurodegenerativa multifactorial representa aproximadamente entre el 60% y el 70% de tod...

Abstract Brain pericytes are mediators of neuroinflammation, as evidenced in vitro, in animal models and humans. We and others have identified the platelet-derived growth factor (PDGF)-BB -PDGF receptor beta (PDGFRB) pat...

Objective To synthesize the available evidence on the effects of constraint-induced movement therapy (CIMT) in children with hemiplegic cerebral palsy (CP), focusing on upper limb functional outcomes and neuroplasticity-...

IntroductionAtopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by immune dysregulation, impaired epidermal barrier function, and recurrent episodes of itching and inflammation. Emerging evidence...