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BackgroundComplex inflammatory phenotypes in children can pose significant diagnostic challenges, particularly when clinical, histopathologic, and immunologic findings do not conform to established diagnoses. We present ...

Fil: Siqueira, Arminda Lucia. Universidade Federal de Minas Gerais; Brasil Fil: Whitehead, Anne. University of Reading; Reino Unido Fil: Todd, Susan. University of Reading; Reino Unido

Background22q11.2 deletion syndrome (22q11.2DS, also known as DiGeorge) affects 1/2,150 individuals. The deletion results in variable clinical phenotypes: thymic hypoplasia or aplasia, hypoparathyroidism, cardiac defects...

Preparar o ambiente de sala para crianças entre quatro e 36 meses tem sido um desafio para a educação infantil - EI. A despeito do fato de crianças pequenas serem tradicionalmente educadas no seio da família, o núm...

Highly evanescent waveguides with a subwavelength core thickness present a promising lab-on-chip solution for generating nanovolume trapping sites using overlapping evanescent fields. In this work, we experimentally stud...

Abstract Management of immune thrombocytopenia (ITP) in dogs and cats is evolving, but there are no evidence‐based guidelines to assist clinicians with treatment decisions. Likewise, the overall goals for treatment of ...

The purpose was to directly assess in-competition thermoregulatory responses in recreational runners during a city marathon conducted in cool, ambient conditions using a two-pill ingestion strategy.

Abstract Background Hydromyelia is a common magnetic resonance imaging (MRI) finding associated with compressive myelopathy caused by intervertebral disc extrusion (IVDE). Objectives To describe the MRI features of hydro...

Abstract Background Guidelines‐driven screening protocols for early cancer detection in dogs are lacking, and cancer often is detected at advanced stages. Hypothesis/Objectives To examine how cancer typically is detect...

Abstract Background Patient reported outcome measure (PROM) use is a marker of high-quality chiropractic care. Limited information exists regarding use of PROMs by United States chiropractors, especially within integrate...

The provision of T cell co-stimulation via members of the TNFR super-family, including OX40 (CD134) and 4-1BB (CD137), provides critical signals that promote T cell survival and differentiation. Recent studies have demon...

Emergency Locator Transmitters (ELTs) are credited with saving hundreds of lives every year in the United States. Following an aircraft accident, these devices transmit an emergency beacon signal to the COSPAS-SARSAT sat...

Abstract Background Recruitment and retention remain persistent challenges in Alzheimer’s disease (AD) clinical trials, particularly as studies increasingly focus on earlier disease stages and require longer participat...

Abstract Background Iron overload promotes atherosclerosis in mice and causes vascular dysfunction in humans with Hemochromatosis. However, data are controversial on whether systemic iron availability within physiologica...

Giftedness is a large topic, covering many domains of activity and diverse manifestations. In this paper, we examine two specific topics: (a) cognitive profiles of gifted children and, (b) musical talent development. The...

ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify ...

Estudiamos la riqueza y composición de especies vegetales en tres afloramientos rocosos (lajas) en Lomerío, Santa Cruz, Bolivia, dentro de un bosque seco tropical. Determinamos la variación de la vegetación desde el ...

Evidence from both GWAS and clinical observation has suggested that certain psychiatric, metabolic, and autoimmune diseases are heterogeneous, comprising multiple subtypes with distinct genomic etiologies and Polygenic R...

Abstract Background Detection of free light chains (fLC) in animals relies on protein electrophoresis or the Bence‐Jones protein test on urine. Objective To describe the detection of both serum fLC (sfLC) and urine fLC...

Abstract Patient navigation is a promising intervention that could improve follow-up of abnormal fecal immunochemical test (FIT) results in colorectal cancer (CRC) screening. We describe changes in navigation activities ...

Introduction Early open fracture management aims to minimise the risk of complications. For the most severe open fracture wounds, multiple irrigation and debridement surgeries are required to overcome severe wound contam...

Abstract Congestion pricing effectively manages road travel demand but raises affordability concerns for lower-income groups. This study evaluates potential implementations of cordon pricing in downtown San Francisco and...

ABSTRACT Herbicide target site resistance in polyploid species is more complex than in diploids due to potential subgenome interactions. This study characterized mutations in the ALS gene across distinct subgenomes of he...