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Objective: Brain metastases (BMs) are the most common intracranial tumors in adults and represent a major cause of morbidity and mortality in patients with systemic malignancies. This study aimed to evaluate the clinical...

Abstract Background Lesions causing refractory epilepsy, often associated with temporal lobe epilepsy (TLE), can be undetectable on standard magnetic resonance imaging (MRI) in dogs. Automated brain volumetry, widely use...

Stimulated Raman scattering (SRS) microscopy is a fast Raman imaging technique that combines the molecular specificity of vibrational spectroscopy with the high spatial resolution and speed of laser-scanning microscopy. ...

The need for early and precise identification of abnormalities has made the detection and classification of brain tumours essential components of medical diagnosis. Because brain tumours are naturally complex and can hav...

BackgroundAttention deficits often persist after mild traumatic brain injury (mTBI), limiting recovery despite normal imaging. Transcranial direct current stimulation (tDCS) has emerged as a non-invasive therapeutic opti...

Abstract Purpose Intraoperative brain bulge (IOBB) is a serious and potentially life-threatening surgical complication. This study aimed to examine the predictive value of the hematoma thickness-to-midline shift (HT/MS) ...

High Angular Resolution Diffusion Imaging (HARDI) is a type of brain imaging that collects a very large amount of data, and if many subjects are considered then it amounts to a big data framework (e.g., the human connect...

BackgroundFrailty is significantly more prevalent in individuals with Parkinson’s disease (PD) than in general population, yet the underlying neuropathophysiological mechanisms remain poorly understood. This study aime...

Abstract Significant changes occur in brain structure and cognition during adolescence. Investigating their association can provide insight into brain-based cognitive development, yet previous studies are limited by narr...

Abstract Contrast enhancement technique is a prevalent problem in aiding interpretation of Magnetic Resonance Imaging (MRI) images. A low contrast MRI image may prove to be problematic in identifying medical problems suc...

The mind has puzzled humans for centuries, and its disorders, such as psychoses, have caused tremendous difficulties. However, relatively recent biotechnological breakthroughs, such as DNA technology and neuroimaging, ha...

Frontal and parietal regions are associated with some of the most complex cognitive functions,and several frontoparietal resting state networks can be observed in wakefulness. We used functional magnetic resonance imagin...

Abstract Half of all newborn neurons in the developing brain are removed via efferocytosis - the phagocytic clearance of apoptotic cells. Microglia are brain-resident professional phagocytes that play important roles in ...

Abstract Background The diagnosis of idiopathic epilepsy (IE) in dogs is based on exclusion of other potential causes of seizures. Recently, a novel magnetic resonance imaging (MRI) sequence that utilizes a variant of th...

Abstract Human social behaviors involve complex interactions between individuals, and understanding how interbrain neural activity reflects and predicts these interactions is critical for advancing social cognitive neuro...

ABSTRACT Background Observational studies link insomnia to hippocampal atrophy, yet causal inference remains limited by confounding and reverse causality. While Mendelian randomization (MR) studies have explored sleep‐...

Background and purpose: Stereotactic radiotherapy (SRT) delivers high doses with submillimeter precision to small targets, requiring accuracy in both dose calculation and delivery. This study aimed to perform a dosimetri...

Background The well-known ‘pyrotherapy’ of Julius Wagner-Jauregg might be the beginning of the study on the immunological concepts of schizophrenia. As the primary immune effector cells in the brain, microglia play a...

Parkinson’s disease (PD) is characterized by profound metabolic disturbances in the brain, yet how these alterations vary across brain regions and respond to neuroprotective intervention remains poorly understood. Here...

Abstract Background Diffuse astrocytoma (DA) is the most common intraparenchymal brain tumor, primarily occurring in the frontal and temporal lobes. However, its occurrence in the lateral ventricles is rare. Case present...

Abstract Background Gliomas in dogs remain poorly understood. Objectives To characterize the clinicopathologic findings, diagnostic imaging features and survival of a large sample of dogs with glioma using the Comparativ...

Abstract Background Brain tumor therapeutic responses can be quantified from magnetic resonance images (MRI) using 1‐ (1D) and 2‐dimensional (2D) linear and volumetric methods, but few studies in dogs compare these t...

Lambotte Syndrome (LS) comprises Intrauterine Growth Retardation (IUGR), cerebral dysgenesis, microcephaly, and early mortality. Dandy-Walker Syndrome (DWS) is characterised by a triad of hypoplastic cerebellar vermis, c...

In the growing diversity of human induced pluripotent stem cell (iPSC)-derived models of brain development, we present here a novel method that exhibits 3D cortical layer formation in a reproducible topography of minimal...