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The current number of emerging contaminants worldwide may reach tens of thousands. However, research on the extra-pulmonary toxicity induced by combined exposure of extremely low-dose emerging pollutants remains extremel...

Abstract Background Understanding of equine herpesvirus‐1 (EHV‐1) myeloencephalopathy (EHM) is complicated by disparities among studies. Objective Compare clinical findings and outcome in horses involved in 2 recent ...

Kaposi Sarcoma (KS) is among the most angiogenic cancers in humans and an AIDS-defining condition. KS-associated herpesvirus (KSHV) is necessary for KS development, as is vascular endothelial growth factor (VEGF-A). DLX1...

Lung fibrosis is a severe disease with limited therapeutic options. The vascular niche is critical for lung function and fibrotic diseases, but the mechanisms by which endothelial cells (ECs) are regulated during lung in...

OBJECTIVE: Receiving urgent hemodialysis (HD) in end-stage renal disease (ESRD) patients significantly increases morbidity and mortality. We aimed to explore the factors involved in the development of urgent hemodialysis...

In this report, we describe a case of fibrillary glomerulonephritis associated with thyroid papillary microcarcinoma arising in a 54-year-old female patient suffering from Hashimoto’s thyroiditis. The patient presented...

Abstract Transition from the transient hyaloid vasculature to the mature retinal vascular network is a critical step in mammalian eye development. While WNT7B signaling in endothelial cells regulates programmed hyaloid v...

Abstract Since age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in the aging population, it is a significant global health concern. Although anti-vascular endothelial growth...

Abstract Background Laccases (LACs) are multicopper oxidases that play vital roles in lignin polymerization, cell wall formation, and various stress responses in plants. Despite their importance, genome-wide investigatio...

Abstract Background Ferns, comprising epiphytic, aquatic, and terrestrial varieties, are good models to investigate plant terrestrialization. Vascular tissue represents a significant development in the terrestrial adapta...

HOPX (homeodomain-only protein), a member of the homeodomain family, is involved in various developmental processes and immune regulation. This study highlights HOPX expression in human placenta and its potential role in...

Mild cognitive impairment (MCI) and dementias, such as Alzheimer’s disease (AD)-induced dementia and vascular dementia, are major public health burdens. The blood-brain barrier (BBB) disruption, systemic inflammation, ...

Abstract Background Equine herpesvirus myeloencephalopathy (EHM) has severe impact on the sport horse population. Objective Study the influence of EHM on the likelihood of affected horses to return to their previous perf...

Durante o processo de assimilação e uso dos alimentos, diferentes respostas metabólicas podem ser desenvolvidas pelo organismo dos animais. Estas respostas são fruto da integração de mecanismos complexos, que envol...

There are multiple receptors for vasopressin (ADH) named the V1a, V1b, and V2 receptors. The V2 receptors primarily mediate the antidiuretic response, while V1a and V1b receptors principally cause vasoconstriction and me...

Although photothermal therapy (PTT) has demonstrated its clinical value and adaptability, it still requires imaging guidance to motivate the development of precise and effective treatment. For PTT, high-resolution visual...

IntroductionIntraoperative software assistance is gaining increasing importance in laparoscopic and robot-assisted surgery. Within the user-centred development process of such systems, the first question to be asked is: ...

Coronary artery ectasia (CAE) is a vascular lesion characterized by abnormal dilation of the coronary arteries, with complex pathogenesis and diverse clinical manifestations. CAE can be classified into primary and second...

The effects of sclerocorneal limbal stem cell autograft transplantation in dogs with corneal wounds were studied. Eighteen dogs were divided in two groups (GI and GII). The animals of GI (n=12) underwent limbal transplan...

Understanding how socioeconomic development modulates trait–environment linkages in the Anthropocene, particularly its mechanistic role in reshaping the relative importance of climate versus soil drivers, remains poorl...

Abstract Subarachnoid hemorrhage (SAH) is an extremely lethal cerebrovascular emergency that can lead to severe long term neurological deficits. Modern research evidence indicates that the incidence of SAH varies signifi...

Background: Numerous studies have been conducted to examine the growth factors capable of exerting simultaneous effects on the vascular and metabolic components of the pathogenesis of diabetic retinopathy (DR). Purpose: ...

Maria Hee Jung Park Frausing,1– 3 Morten Schmidt,2,4 Ole Dan Jørgensen,5,6 Frederikke Nørregaard Jakobsen,7 Frederik Mikkelsen,1,2 Jacob Moesgaard Larsen,8 Charlotte Ellen Larroudé,9 Berit Thornvig Philbert,10 Jens ...

Abstract Vascular dysfunction, including endothelial cell (EC) senescence and hypertension, is a hallmark of metabolic syndrome, yet its underlying mechanisms remain unclear. Here, we show that metabolic stress upregulat...