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We aimed to investigate the effects of treatment with amlodipine and valsartan, on markers of bone remodeling in newly diagnosed hypertensive adults. Forty-three subjects with newly diagnosed were included in the study. ...

IntroductionAdrenal incidentalomas are an increasing clinical concern and, while most are non-functioning adrenal adenomas (NFAA), a relevant subset is associated with mild autonomous cortisol secretion (MACS), condition...

Background: Bone turnover markers are useful to evaluate bone loss and monitor anticatabolic treatments in a short period. The effectiveness of saliva to reflect changes in bone turnover markers during the early administ...

Background Postmenopausal osteoporosis (PMOP) is characterized by exacerbated bone resorption and inadequate bone formation, with macrophage-driven inflammation playing a key role. However, how immunometabolic reprogramm...

Abstract Background Midlife women are facing many healthcare challenges, including unmet needs in screening and preventive care. Nurse-led risk-based model in primary healthcare settings prioritizes preventive care and s...

La alimentación de las personas en la época moderna se ha visto asociada al incremento dediversas patologías crónicas, tales como isquemia coronaria, hipertensión, cáncer, diabetes,cirrosis, osteoporosis, obesidad,...

Background: Yerba mate (YM) drinking is associated with higher lumbar spine and femoral neck bone mineral density (BMD) in postmenopausal women. We analyzed its effect on total hip BMD and reported the contribution of th...

PURPOSE: This study was performed to determine risk factors influencing the development of osteonecrosis after renal transplantation. METHODS:We retrospectively evaluated osteonecrosis in 308 kidney graft recipients (...

Low bone mineral density (BMD) is one of the risk factors for bone fracture. The incidence of bone fracture is highest among patients with chronic renal failure. There is little data about the BMD of patients undergoing ...

OBJECTIVE: The prevalence of atherosclerosis and osteoporosis increase with age. An association has been demonstrated between cardiovascular diseases and low bone mineral density. We aimed to investigate the association ...

Dual-energy X-ray absorptiometric bone mineral density (DXA BMD) is a strong predictor of fracture risk in untreated patients. However, previous patient-level studies suggest that BMD changes explain little of the fractu...

Tenofovir is one of the first-line new generation antiviral agents commonly used in chronic hepatitis B treatment. While being considered an effective and safe treatment, the most important side effect known is nephrotox...

The aim of this study was to measure osteoporosis in the right heel bone. A total of 123 Iraqi men and women with low back pain (LBP) participated in the study (18 males and 105 females). Quantitative Ultrasound (QUS) wa...

OBJECTIVE: Chronic kidney disease - mineral and bone disorder (CKD -BMD) is a worldwide challenge in hemodialysis patients (HD). Widespread use and improved methods of HD may have changed the spectrum of locomotor system...

OBJECTIVE: Cardiovascular diseases are the main reason of death in patients with renal transplantation (Rtx). Osteoprotegerin (OPG) is produced by osteoblasts and is linked to increased cardiovascular risk in Rtx. OPG ac...

Bone mineral density (BMD) is the tool for diagnosing osteoporosis in older adults. However, BMD alone is not sufficient for deciding who should be given treatment at either the individual patient or the public health le...

Osteoporosis constitutes a major public health problem through its association with age related fractures. Fracture rates are generally higher in caucasian women than in other populations. Important determinants include ...

Medicarpin (MED) is an isoflavonoid compound derived from traditional Chinese medicine (TCM). Numerous preliminary experimental studies have shown that MED has significant pharmacological effects in the treatment of canc...

Biphosphonates (BP), synthetic analogues of inorganic pyrophosphate, potently inhibit skeletal resorption by suppressing the recruitment and activity of osteoclasts and shortening their life span and decreasing bone loss...

Abstract Objectives Abnormal osteogenic differentiation of BMSCs is a core factor in osteoporosis (OP). This study investigates how miR-326 regulates osteogenic differentiation of hBMSCs by targeting NAT10, thereby influ...

Enfermedades tales como osteoporosis, osteonecrosis, osteogénesis imperfecta y tumores óseos se caracterizan por pérdida de masa ósea con deterioro de la microarquitectura lo que se asocia con riesgo de fractura en l...

Los objetivos del presente trabajo de tesis fueron: Objetivo General Investigar los mecanismos patogénicos de los AGEs en modelos de células óseas en cultivo, así como el rol de agentes anti-resortivos como los bi...

D-003 is a mixture of higher fatty acids purified from sugarcane wax with antiosteoporotic effects in ovariectomized (ovx) rats. Omega-3 fatty acids (Ω-3FA) have shown bone-protective effects. This study compared the ef...

Se discuten brevemente los aspectos generales de la bioquímica y toxicología del flúor y del anión fluoruro, analizándose también los posibles modos de acción del fluoruro en la estabilización de la fase inorgán...