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Hematology is an important pathological and diagnostic tool. This paper describes the hematological parameters of 76 specimens of Hoplias malabaricus infested with monogenean parasites, which were collected from two lago...

Abstract Introduction Hepatitis C virus (HCV) infection is related with several liver diseases such as cirrhosis and hepatocellular carcinomas, leading to more than 0.5 million deaths every year and to a great global bu...

Jiahui Zhang,1– 3,* Junran Tong,1– 3,* Yang Sun,4,* Jinpeng Sun,1– 3 Ran Gao,1– 3 Di Sun,5 Xiaopeng Guo,6 Yumiao Wei1– 3 1Department of Cardiology, Union Hospital, Tongji Medical College...

Abstract Objective To analyze the impact of portal vein resection (PVR) and hepatic artery resection (HAR) on the short-term and long-term outcomes of patients with hilar cholangiocarcinoma after surgery. Methods A compr...

Aim. To assess the structural and functional myocardial characteristics in patients with unstable angina (UA) and post-COVID-19 syndrome (PACS), stratified by smoking status. Materials and methods. The study included ...

Myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) are natural compounds involved in many biological pathways. Since the discovery of their involvement in endocrine signal transduction, myo-Ins and D-chiro-Ins sup...

BackgroundHypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiovascular conditions, which may be linked to ion channel dysfunction. In decades, Genetic studies in HCM patients have shown that multipl...

AimTo clarify the molecular mechanisms through which lobetyolin (LT) modifies the gut microbiota-bile acid axis to multitarget the regulation of hyperandrogenism, insulin resistance, chronic low-grade inflammation, and e...

Abstract Parathyroid hormone 1 receptor (PTH1R) signaling is critical for mineral ion homeostasis and skeletal development. Although its role in tooth root formation and eruption is established, its specific functions in...

Abstract Addictive behaviors are not limited to drugs use, but also include certain daily behaviors that can cause gratification. Their progression to more severe pathological patterns entails grave consequences for the ...

ABSTRACT Cadmium (Cd) is a pervasive environmental pollutant known for its detrimental effects on male reproductive health, causing testicular damage, hormonal imbalances, and reduced fertility. This study investigates t...

A neoplasia intraepitelial da vulva (VIN) é uma denominação que foi introduzida incialmente pela International Society for Study of Vulvo-vaginal Diseases (ISSVD) e reconhecida posteriormente pela International Societ...

Abstract Background Human patients with Ehlers‐Danlos syndrome (EDS) are categorized into subtypes based on causative genetic variants and phenotypes. The classical form of EDS, primarily caused by variants in COL5A1 o...

Gambling disorder or pathological gambling is a psychiatric disorder with severe and wide-ranging consequences for the affected individual and their surroundings. While no pharmacological treatment has yet been officiall...

ABSTRACT This report describes an outbreak of exogenous organophosphate poisoning in a flock of Lacaune sheep. Forty sheep had signs of delayed poisoning after accidental exposure to an organophosphate-based insecticide ...

Abstract Introduction Intravenous leiomyomatosis is a benign and rare condition that can result in cardiac events with fatal outcomes when left untreated. Intravenous leiomyomatosis is probably underestimated because t...

Background/Aim: Root resorption (RR) refers to a cellular response resulting in loss of hard and soft dental tissue due to injury, irritation of the periodontal ligament, and/or tooth pulp. Typically, it is considered a ...

Epilepsy is a debilitating neurological disorder characterized by recurrent seizures, affecting millions of patients worldwide. Retrospective studies in temporal lobe epilepsy (TLE) patients have shown a high incidence o...

Abstract Mutations in the presenilin (PS/PSEN) genes cause early-onset familial Alzheimer’s disease (AD) by enhancing cerebral accumulation of amyloid-β (Aβ) peptides and microtubule-associated protein tau (MAPT). Ho...

BackgroundThe study assessed the epigenetic regulation and the role of microRNA (miR) expression in locally advanced triple negative breast cancers (TNBC) and comparison with the clinico-pathological variables and surviv...

There is an increasing heavy disease burden of major depressive disorder (MDD) globally. Both high diagnostic heterogeneity and complicated pathological mechanisms of MDD pose significant challenges. There is much eviden...

Post-traumatic stress disorder (PTSD) is a severe neuropsychiatric disorder characterised by re-experiencing, avoidance and hyperarousal. Memory abnormalities manifested as intrusive thoughts and prolonged distressful em...

IntroductionMetabolism-associated fatty liver disease (MAFLD) has emerged as a severe worldwide public health burden with insufficient available clinical therapeutic strategies, which underscores the urgent demand for sa...

Abstract Background This study aims to evaluate the effectiveness and real-world applicability of total neoadjuvant therapy (TNT) in patients with locally advanced rectal cancer (LARC), focusing on pathological complete ...