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A Comparative Study Between Lipid A Extracted from Salmonella typhi and Pseudomonas Aeruginosa to Demonstrate the Extent of its Stimulation of Immune System

ISSN: 1812125X · Editor / fuente: University of Mosul, College of Education for Pure Science

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GATA2 Deficiency Presenting with Severe Immune Dysregulation
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GATA2 Deficiency Presenting with Severe Immune Dysregulation
Aria Bruton Joe et al · Rockefeller University Press · 2026 · ISSN 3065-8993
BackgroundGATA2 deficiency results from heterozygous pathogenic variants in the GATA2 gene, which encodes a zinc-finger transcription factor essential for hematopoietic stem and progenitor cell development. It is a highl...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Immunological landscape of nanotechnology-based depression research: a bibliometric analysis of neuroinflammation and immune modulation
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Immunological landscape of nanotechnology-based depression research: a bibliometric analysis of neuroinflammation and immune modulation
Zi-yi Guo et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
PurposeImmune dysregulation and neuroinflammation have been increasingly implicated in depression, and nanotechnology-based approaches are being actively explored for targeted delivery and immunomodulation. However, a sy...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Impact of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitor on Immune-Inflammatory Responses in the Acute Phase of Ischemic Stroke
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Impact of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitor on Immune-Inflammatory Responses in the Acute Phase of Ischemic Stroke
Li Z et al · Dove Medical Press · 2026 · ISSN 1178-7031
Zhenzhen Li,1,* Cong Sun,2,* Qing Zhang,1,* Lifan Ji,3 Yiting Zhang,1 Shuo Li,1 Mengmeng Gu,1 Jie Gao,1 Zhihui Huang,1 Meng Wang,1 Junshan Zhou,1 Lin Zhu,1 Teng Jiang,1 Qing Zhou,4 Qiwen Deng1 1De...
LCC TENDOlBhdGhvbG9neQ~~; LCC:Therapeutics. PharmacologyIdioma eng
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Lactobacillus casei: Influence on the innate immune response and haemostatic alterations in a liver-injury model
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Lactobacillus casei: Influence on the innate immune response and haemostatic alterations in a liver-injury model
Haro, Ana Cecilia et al · National Research Council Canada-NRC Research Press · 2009 · ISSN 0008-4166
Lactobacilllus casei CRL 431 has the ability to modulate the local and systemic immune responses, which are significantly involved in liver injury caused by hepatotoxins. This work was conducted to determine whether L. c...
Idioma eng
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Mechanical gating of tendon fibrogenic transcription in systemic sclerosis
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Mechanical gating of tendon fibrogenic transcription in systemic sclerosis
Amro A. Hussien et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Fibrosis arises from aberrant tissue repair in systemic sclerosis and is characterized by progressive stiffening across multiple tissues, including tendons. How altered tissue mechanics sustain fibrotic remodeli...
LCC TENDOlNjaWVuY2U~Idioma eng
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Neuro-immune interactions underlying autoimmune diseases: insights from brain imaging data
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Neuro-immune interactions underlying autoimmune diseases: insights from brain imaging data
Junxiang Gu et al · BMC · 2026 · ISSN 1756-6606
Abstract Autoimmune diseases (AIDs) result from intricate interactions among genetic, environmental and immune factors, with emerging evidence underscoring the role of the central nervous system (CNS) in their pathogenes...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Pannexin-1–mediated ATP signaling as a driver of immune communication and chronic inflammation in HIV infection
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Pannexin-1–mediated ATP signaling as a driver of immune communication and chronic inflammation in HIV infection
Emma K. Kaufman et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Chronic inflammation is a hallmark of many diseases, including persistent viral infections. In human immunodeficiency virus (HIV) infection, sustained immune activation contributes to end-organ damage and non-AIDS comorb...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Prognostic implications of PD-L1 expression in gastric cancer: systematic review and meta-analysis of studies published between 2018 and 2025
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Prognostic implications of PD-L1 expression in gastric cancer: systematic review and meta-analysis of studies published between 2018 and 2025
Gulnaz Yessultanova et al · BMC · 2026 · ISSN 1471-2407
Abstract Background Programmed death-ligand 1 (PD-L1) is widely used as a predictive biomarker for response to immune checkpoint inhibitors in gastric cancer (GC); however, its independent prognostic value for overall su...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Que/n-HA/PGCL microspheres orchestrate bone repair via context-dependent osteoimmune mechanisms: a transcriptomic dissection of direct and immune-mediated signaling
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Que/n-HA/PGCL microspheres orchestrate bone repair via context-dependent osteoimmune mechanisms: a transcriptomic dissection of direct and immune-mediated signaling
Chunyu Han et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
IntroductionBone defect repair remains a clinical challenge due to the complex inflammatory microenvironment that regulates mesenchymal stem cell fate.MethodsBased on our previous work demonstrating that quercetin-loaded...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Real-World Patient Characteristics, Burden, and Quality of Life in C3 Glomerulopathy and Primary Immune Complex Membranoproliferative GN
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Real-World Patient Characteristics, Burden, and Quality of Life in C3 Glomerulopathy and Primary Immune Complex Membranoproliferative GN
Fernando Caravaca-Fontan et al · Wolters Kluwer - Lippincott Williams & Wilkins · 2026 · ISSN 2641-7650
Key Points. C3 glomerulopathy and primary immune complex-mediated membranoproliferative GN lead to a significant clinical, economic, and health care burden among affected patients and their families. C3 glomerulopathy an...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBnZW5pdG91cmluYXJ5IHN5c3RlbS4gVXJvbG9neQ~~Idioma eng
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Spatial and functional heterogeneities shape collective behavior of tumor-immune networks.
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Spatial and functional heterogeneities shape collective behavior of tumor-immune networks.
Daniel K Wells et al · Public Library of Science (PLoS) · 2015 · ISSN 1553-734X
Tumor growth involves a dynamic interplay between cancer cells and host cells, which collectively form a tumor microenvironmental network that either suppresses or promotes tumor growth under different conditions. The tr...
LCC LCC:Biology (General)Idioma eng
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Combined Prognostic Value of Nutritional and Inflammatory Indices for Predicting Functionally Significant Coronary Stenosis Verified by FFR: The PNI–SII–GINI Study
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Combined Prognostic Value of Nutritional and Inflammatory Indices for Predicting Functionally Significant Coronary Stenosis Verified by FFR: The PNI–SII–GINI Study
Aydın MZ et al · Dove Medical Press · 2026 · ISSN 1178-7031
Mehmet Zafer Aydın,1 Can Baba Arin,2 Mehmet Kamil Teber,1 Zülfiye Kuzu,1 Mustafa Gök,1 Ishak Ahmed Abdi3 1Department of Cardiology, Kayseri City Training and Research Hospital, Kayseri, Turkey; 2Department o...
LCC TENDOlBhdGhvbG9neQ~~; LCC:Therapeutics. PharmacologyIdioma eng
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Low-frequency ultrasound treatment reduces susceptibility to Salmonella infection in aged mice
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Low-frequency ultrasound treatment reduces susceptibility to Salmonella infection in aged mice
Parisa Zangoui et al · American Society for Microbiology · 2025 · ISSN 0021-9193
ABSTRACT Increased susceptibility of elderly populations to infection is a major concern, as recently experienced by the coronavirus pandemic. Therefore, the treatment of infected elderly individuals is of immediate inte...
LCC LCC:MedicineIdioma eng
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Modulating offspring responses: concerted effects of stress and immunogenic challenge in the parental generation
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Modulating offspring responses: concerted effects of stress and immunogenic challenge in the parental generation
Giayetto, Octavio et al · Company of Biologists · 2020 · ISSN 0022-0949
The perception, processing and response to environmental challenges involves the activation of the immuno-neuroendocrine (INE) interplay. Concerted environmental challenges might induce trade-off when resource allocation...
Idioma eng
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Searching for the one(s): Using Probiotics as Anthelmintic Treatments
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Searching for the one(s): Using Probiotics as Anthelmintic Treatments
Saracino, María Priscila et al · Frontiers Media · 2021 · ISSN 1663-9812
Helminths are a major health concern as over one billion people are infected worldwide and, despite the multiple efforts made, there is still no effective human vaccine against them. The most important drugs used nowaday...
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Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy
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Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy
Fengrui Zhou et al · Springer · 2026 · ISSN 2730-6011
Abstract Background Hepatocellular carcinoma (HCC) is a critical condition characterized by unchecked cellular growth in the liver, often leading to systemic inflammation and organ failure. Although its complex molecular...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Metabolic control of immunity and inflammation: Mitochondrial dynamics, pharmacological targets, and therapeutic opportunities
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Metabolic control of immunity and inflammation: Mitochondrial dynamics, pharmacological targets, and therapeutic opportunities
Chunling Wang et al · Elsevier · 2026 · ISSN 1096-1186
Immune responses and inflammation are not stand-alone processes linearly regulated by the canonical signaling pathways but complex systems biology events, which are deeply rooted in the metabolic state of cells and dynam...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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Precision immunotherapy for head and neck cancer: therapeutic combinations, biomarker strategies, and translational challenges
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Precision immunotherapy for head and neck cancer: therapeutic combinations, biomarker strategies, and translational challenges
Kohei Okuyama et al · BMC · 2026 · ISSN 1476-4598
Abstract Immune checkpoint inhibitors (ICIs) have fundamentally altered the therapeutic paradigm for head and neck squamous cell carcinoma (HNSCC); however, durable clinical benefit remains limited to biologically define...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Probiotic activity of Enterococcus faecalis CECT7121: effects on mucosal immunity and intestinal epithelial cells
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Probiotic activity of Enterococcus faecalis CECT7121: effects on mucosal immunity and intestinal epithelial cells
Castro, Marisa Silvia et al · Wiley Blackwell Publishing, Inc · 2016 · ISSN 1117-1129
Aims: To analyse the effect of Enterococcus faecalis CECT7121 on intestinalepithelial cells (IECs) and its effects on the mucosal immune response.Methods and Results: Enterococcus faecalis CECT7121 showed a high adhesion...
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Severe neuromyelitis optica spectrum disorder induced by pucotenlimab: a case report and literature review
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Severe neuromyelitis optica spectrum disorder induced by pucotenlimab: a case report and literature review
Ziyu Zhang et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Immune checkpoint inhibitors (ICIs) have been widely utilized in patients with cancer and established as a standard therapeutic modality for various solid tumors. Although generally well tolerated, ICIs can induce unique...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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The effect of organic acids mixture in the form of glycerids on the regulation of intestinal barrier function in piglets using SCFA-M: analysis of molecular markers
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The effect of organic acids mixture in the form of glycerids on the regulation of intestinal barrier function in piglets using SCFA-M: analysis of molecular markers
Andrii Gavrylenko et al · Institute of Animal Biology NAAS · 2026 · ISSN 1681-0015
The functions of the intestinal system are crucial for animal health and productivity, as they ensure digestion, nutrient absorption, immune homeostasis, and microbiota regulation. Molecular markers of the intestinal sys...
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Advances in cryo-EM that have shaped mechanistic models of membrane-attack-complex assembly and regulation
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Advances in cryo-EM that have shaped mechanistic models of membrane-attack-complex assembly and regulation
Dylan P. Noone et al · International Union of Crystallography · 2026 · ISSN 2052-2525
The complement system is a blood-based immune network that plays a crucial role in fighting infection and maintaining immune homeostasis. The membrane attack complex (MAC) is a pore assembled from complement proteins tha...
LCC TENDOkNyeXN0YWxsb2dyYXBoeQ~~Idioma eng
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Compositional maturation of the microbiome and adaptive immunity in the postnatal period
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Compositional maturation of the microbiome and adaptive immunity in the postnatal period
Miranda Green et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
IntroductionRecent research has highlighted the role of the gut microbiome in shaping the development and function of the mammalian immune system. Interactions between these complex networks of microbes and host cells se...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Determining the Risk of Developing Severe Sepsis Using Genetic Profiling of Innate Immunity Genes
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Determining the Risk of Developing Severe Sepsis Using Genetic Profiling of Innate Immunity Genes
E.A. Polyakova et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Background and AimsThe immune response to an infectious agent is regulated by a complex network of signaling pathways involving numerous genes encoding inflammatory mediators, proteins of the innate and adaptive immune s...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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