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ABSTRACT Background Low muscle mass is increasingly recognized to extend beyond aging and is closely linked to metabolic dysfunction. Its population‐level burden, ethnic disparities, metabolic clustering and mortality ...

Abstract Background Prognostic assessment in sepsis involves evaluating the dynamic progression of organ dysfunction and the inflammatory response. This study compared the predictive value of serially measured serum HMGB...

Abstract Background Globally, stroke is a leading cause of mortality and disability, affecting approximately 15 million people annually. This study aimed to analyze hospitalizations, deaths, and thrombolysis for ischemi...

OBJECTIVE: We aimed to evaluate the relation of serum Fibroblast Growth Factor 23 (FGF-23), Interleukin 1 beta (IL-1 beta) and Kidney Injury Molecule 1 (KIM-1) levels with progression and mortality rates of patients wi...

Abstract Objective The aim of this study is to evaluate the burden of indirect causes of maternal morbidity/mortality in Brazil. Methods Secondary analysis of a multicenter cross-sectional study conducted in 27 refer...

ABSTRACT Background Sepsis has been defined in humans as the concurrent proven or suspected presence of microbial infection and the systemic inflammatory response syndrome (SIRS). Sepsis is the leading cause of morbidity...

Current risk stratification for Post-cardiac Arrest Syndrome (PCAS) relies mainly on static admission variables and may fail to capture the dynamic systemic evolution. This study aimed to identify trajectory-defined thro...

Background Dermatologic infections complicated by sepsis represent a significant yet understudied cause of mortality in the United States, with evolving epidemiological patterns that warrant investigation. Objective To e...

Introduction: The Neonatal Mortality Rate (NMR) remains high in India despite various advances in neonatal care. A reliable scoring system may help identify sick neonates and facilitate early interventions. The Score for...

Abstract Objective To examine whether long-term opioid use after total knee arthroplasty (TKA) is associated with subsequent risks of major adverse cardiovascular events (MACE) and all-cause mortality in patients with kn...

Abstract Heart failure (HF) and chronic obstructive pulmonary disease (COPD) frequently co-occur, complicating treatment. Concerns about respiratory complications often lead to underuse of β-blockers in this population....

Objective: An urgent hemodialysis (uHD) procedure is performed in acute kidney injury (AKI) with life-threatening complications. In this study, we aimed to investigate the clinical and laboratory findings that were assoc...

BackgroundAcute respiratory distress syndrome (ARDS) secondary to severe acute pancreatitis (SAP) is associated with high mortality; however, dependable biomarkers for early risk assessment remain scarce. The lactate-to-...

Abstract Background Acute Patient Physiologic and Laboratory Evaluation (APPLE) scores have not been reported in cats with diabetic ketoacidosis (DKA). Hypothesis In cats with DKA, APPLE scores will be significantly high...

The wedge clam Donax hanleyanus Philippi, 1845 is a conspicuous member of the sandy beach macrofauna along hundreds of kilometres in the northern coasts of Argentina. Age, growth, mortality, and productivity of this spec...

Abstract Introduction As the population ages, non–ST-segment elevation myocardial infarction (NSTEMI) in the oldest-old poses unique management challenges, yet this group remains underrepresented in clinical trials. He...

Abstract This study investigates the nexus between income inequality and health outcomes in Ethiopia over the period 1970–2024 using a Co-Integrated Vector Autoregressive (CVAR) approach. Employing time series data fro...

Resumen: Introducción: La enfermedad renal crónica (ERC) será la segunda causa de muerte en el mundo en 2100. El Registro Español de Diálisis y Trasplante (REDYT) recopila información sobre la incidencia, la preva...

Objective: D-dimer testing is commonly used in emergency departments (EDs) to rule out thromboembolic events. However, elevated D-dimer levels may also be associated with an increased risk of mortality, independent of th...

Abstract Background Eligibility criteria for lung cancer (LC) screening aim to identify long-term smokers who have exceeded a minimum-risk threshold of having LC, while still having sufficiently long remaining life expec...

ABSTRACT Background and Aims Decubitus ulcers represent a significant public health challenge in China, yet their disease burden remains understudied in the peer‐reviewed literature. This study aims to fill this critic...

Background: The United Network for Organ Sharing mandates a psychosocial assessment of transplant candidates before listing. A quantified measure for determining transplant candidacy is the Psychosocial Assessment of Can...

Background: Chronic hypoxemia in patients with COPD is associated with increased morbidity and mortality. Although arterial partial pressure of oxygen (PaO2) is widely used, it does not adequately reflect systemic oxygen...

Abstract B and T lymphocyte attenuator (BTLA) and herpes virus entry mediator (HVEM) are emerging immune checkpoint molecules implicated in immune dysregulation during critical illness. We investigated the prognostic rel...