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Os polihidroxialcanoatos são poliésteres de hidroxiácidos sintetizados por inúmeras bactérias, como compostos que servem como fonte de carbono intracelular e energia, sendo acumulados na forma de grânulos no cito...

Eugenol (4-allyl-2-methoxyphenol) is a naturally occurring phenol present in many botanical extracts, such as clove, cinnamon, and nutmeg essential oils. The beneficial properties of this compound have been extensively i...

Implants prepared with polymer blends [poly (e-caprolactone)-poly(lactide), PCL-PLA] at different rates were developed from microspheres. Approximately 19% of dexamethasone acetate was encapsulated into the microsphere...

Spherical crystallization (SC) is a promising alternative for improiving micromeritic properties and dissolution rate of active pharmaceutical ingredients. In the present work spherical agglomerates of carvedilol (CAR) w...

To select the suitable concentration level of controlled release polymer for the formulation of predefined extended release formulation based on the solubility behaviour of active substance, we have formulated and evalua...

The purpose of the present research work was to produce a biphasic delivery system for Diclofenac sodium. A dual component tablet made up of a sustained release beads and immediate release tablet coat was prepared by dir...

Oral route of drug administration is the most preferred route of drug administration but this route has its own limitations like pH of gastric media and controlling release rate of water soluble drug. To overcome these l...

The purpose of this work was to design and evaluate a novel vaginal delivery system for the local treatment of vaginal candidiasis. Bioadhesive vaginal films of metronidazole that could be retained in the vagina for prol...

The purpose of this study was to design a novel vaginal delivery system composed of metronidazole microspheres dispersed within a bioadhesive gel. Microspheres were prepared by solvent evaporation method using Eudragit...

The aim of the present study was to develop a sustained release mucoadhesive buccal film of naproxen, which can be used to treat the inflammation in the oral cavity. The mucoadhesive buccal films were prepared by solve...

Las semillas de Cucurbita pepo L., por su elevado porcentaje de aceite fijo, son ricas en ácidos grasos poliinsaturados, fitoesteroles, tocoferoles y carotenoides, empleándose tradicionalmente como antiinflamatorio en ...

En los últimos años, se ha desarrollado un gran interés por la producción de polímeros denominados funcionales o specialties. Los mismos se destacan por poseer algunas propiedades particulares que dan lugar a aplica...

Se estudiaron las variaciones en el perfil de polifenoles de Tripodanthus acutifolius (Ruiz et Pav.) Tiegh., en relación con la infección causada por "cochinilla", analizando comparativamente los extractos metanólico...

The aim of the study was to formulate and evaluate controlled release microspheres. Ciprofloxacin HCl, belonging to the class of fluroquinolones, was chosen as the model drug. The drugloaded microspheres were prepared wi...

"El presente estudio de pre factibilidad se lleva a cabo en la empresa Resinpol S.A.I.C., la cual se encuentra ubicada en Capilla del Señor, Provincia de Buenos Aires, y se dedica a la producción de resinas sintéticas...

Materiais poliméricos foram propostos no desenvolvimento de novos excipientes potencialmente biodegradáveis para liberação colo-específico de fármacos. Oligossacarídeo α-gluco-oligossacarídeo (α- GOS/Bioecolian...

Os sistemas matriciais são de fácil obtenção e custo reduzido frente a outros sistemas de liberação controlada de fármacos, constituindo-se uma alternativa simples no desenvolvimento de formulações eficazes. Den...

The present study was undertaken to investigate the effect of nature of polymers like HPMC, carbopol-934P and their content levels on the release profiles of water soluble drug, diclofenac potassium. For this purpose, di...

Debido a la astringencia que manifiesta Maytenus vitis-idaea Griseb. (Celastraceae), se abordó el estudio de los taninos condensados presentes en los extractos acuosos obtenidos de hojas frescas y secas, determinándose...

The deposition of chlorhexidine base on thermosensitive N-isopropylacrylamide polymeric microparticles was assessed in this study using energy dispersive X-ray spectrometry (EDXS) in scanning electron microscopy (SEM) se...

Se ensayaron diversos polímeros de la povidona (PVP) con el objeto de determinar el tipo, técnica operativa y proporciones más adecuadas para dispersar extractos crudos vegetales en agua administrables en forma oral o...

Transdermal drug delivery systems of venlafaxine hydrochloride were prepared by using combination of hydrophilic (HPMC E15) and hydrophobic (ERS100 and ERL 100) polymers in 1:5, 2:4, 3:3, 4:2, 5:1 ratios by solvent casti...