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Background: Phytolacca tetramera is an endemic plant from Argentina that is currently at serious risk because its environment is subjected to a high anthropic impact. A previous study has shown that berry extracts obtain...

Chlorite dismutase (Cld) is a b-type hemecontaining enzymethat catalyzes the reduction of chlorite into chloride plus dioxygen. This enzyme has gained attention because it can be used in the development of bioremediation...

Abstract Background Skin disorders are widespread, and there is increasing demand for reliable, standardized herbal therapeutics. Kumkumadi Tailam, a classical Ayurvedic polyherbal oil formulation, incorporates several b...

Abstract Background Prostate cancer (PCa) is a common malignant tumor in men, with a high incidence rate, posing a serious threat to human health and quality of life. Neddylation is a major post-translation modification,...

Abstract Background Lichens produce several secondary metabolites with significant biological and pharmacological activities, among which usnic acid (UA) is particularly notable. This study aimed to investigate the cytot...

Abstract Background Adipose tissue is increasingly recognized as an important component of the tumor microenvironment of colorectal cancer (CRC) and actively contributes to the progression of the disease. Adipose stem ce...

A simple and rapid procedure has been developed and validated for the simultaneous determination of benzoylecgonine and ecgonine methyl ester in human urine samples. After extraction and sample cleanup by solid-phase ext...

The present research work describes comprehensive stress testing of eprosartan mesylate (EM) according to ICH guideline Q1A (R2), and development of a stability-indicating reversed phase ultra performance liquid chromato...

Fast release capsules, containing sertraline hydrochloride, pregelatinized maize starch and microcrystalline cellulose were formulated. For this purpose, different technological assays were elaborated being the formula...

The objective of reducing analysis time and maintaining good efficiency, there has been substantial focus on high-speed chromatographic separations. Recently, commercially available ultra performance liquid chromatograph...

Crude drug and different extracts of Achyrocline satureioides (Lam.) DC., A. tomentosa Rusby, Gnaphalium cheiranthifolium Lam. and G. gaudichaudianum DC. (Gnaphalieae: Asteraceae) are widely used in South America mainly ...

O método analítico por espectrofotometria no ultravioleta foi desenvolvido e validado, segundo as normas vigentes das agências regulatórias, para a quantificação de metronidazol gel vaginal. Utilizou-se N-N-dimet...

Existe a tendência atual de desenvolvimento de fotoprotetores possuindo reduzida concentração de filtros químicos e de proteção elevada frente às radiações UVA e UVB. O presente trabalho propôs a obtenção e a...

Los nematodos parásitos causan enfermedades importantes al hombre y a los animales domésticos. El control de estas infecciones se apoya fundamentalmente en el tratamiento con antihelmínticos; lamentablemente, se han i...

El desarrollo de suplementos nutricionales en forma sólida (tabletas, cápsulas y granulados) a partir de fuentes naturales, resulta un área de constante interés en la investigación del farmacéutico, con la finalida...

A cetirizina é um fármaco anti-histamínico encontrado no mercado brasileiro sob a forma de comprimidos e cápsulas magistrais. O presente estudo objetivou desenvolver um método de dissolução, bem como avaliar a q...

El diazepam se absorbe rápida y completamente después de la administración oral y atraviesa la barrera placentaria; su tasa de penetración en el tejido placentario es de 31,5% a las 4 horas, su vida media es prolonga...

Fil: Goya, María Eugenia. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Cronobiología; Argentina. Los ritmos circadianos están basados en relojes endógenos que les permiten a ...

El cieno de acetileno se ha venido utilizando en los últimos años en diversas aplicaciones biológicas y se han realizado diversas pruebas para valorar su posible toxicidad. El objetivo del presente trabajo es profundi...

Se prepararon 16 nuevas oxazinas con potencial actividad antiparasitaria por la reacción de Diels-Alder partiendo de dos series de dienos con estructuras diferentes (purpurogalina y derivados de cis-3,5-ciclohexadien- 1...

It is well known that microbiologically influenced corrosion (MIC) is a serious issue in the oil and gas industry. This process is caused by a mixture of microorganisms, including aerobic and anaerobic bacteria. Among th...

Se sintetizaron diez moléculas de alcamidas usando la enzima Novozym lipasa B de Candida antartica en tolueno anhidro. Como sustrato de la reacción se utilizaron ácidos grasos y ésteres de ácidos grasos en presenc...

A B-lapachona (BLAP) é um fármaco antitumoral recentemente avaliado em ensaios clínicos com promissores resultados preliminares. O objetivo deste estudo foi validar um método espectrofotométrico para a rotina de d...