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Current scientific endeavours in the field of geroscience have begun to reveal how factors such as exercise could modulate the brain aging process. In this review, we ask how exercise could potentially modulate aging, an...

Despite the well-documented benefits of exercise for adolescents’ physical and mental health, exercise remains an underutilized strategy for improving the health of trans adolescents. This is notable because, compared ...

This randomized controlled pilot study aimed to investigate the therapeutic effects of Baduanjin exercise – a traditional Chinese mind-body practice integrating gentle movements, diaphragmatic breathing, and mindfuln...

To assess the effects of a wearable-sensor-assisted multicomponent exercise program on physical fitness, cognition and quality of life in a practical setting involving frail older adults.

This study aimed to investigate the protective effects and underlying mechanisms of aerobic intermittent exercise on cognitive impairment by PM2.5 exposure.

Parkinson’s disease (PD) is a neurodegenerative disorder with increasing prevalence into older age. Aerobic exercise (AE) is the most commonly prescribed exercise for PD, although an optimal protocol is undefined. This...

To evaluate the effect of moderate-to-high-intensity aerobic exercise performed the day before chemotherapy session on cancer-related fatigue (CRF) and to compare active vs. sedentary behaviors over the subsequent 5 day...

Multiple Sclerosis (MS) is a chronic neuroinflammatory autoimmune characterized by inflammation-induced lesion formation after immune cell infiltration into the central nervous system. T cells play an intriguing role in...

The incidence of ischemic stroke continues to rise globally, however, regular physical activity before stroke onset significantly lowers its occurrence. Here, we evaluated whether low-intensity exercise preconditioning c...

‘OMICs encapsulates study of scaled data acquisition, at the levels of DNA, RNA, protein, and metabolite species. The broad objectives of OMICs in biomedical exercise research are multifarious, but commonly relate to b...

Aerobic exercise training can increase skeletal muscle mitochondrial content. Supine exercise training with legs above the heart potentially augments these increases. However, the impact of supine exercise training on mi...

This study examined the effects of step-reduction and subsequent step-recovery and exercise rehabilitation on systemic metabolism in older adults.

People living with severe mental illness have a reduced life expectancy when compared to the general population largely due to physical health comorbidities. Exercise is a valuable, evidence-based component of mental hea...

Lipid droplets (LDs) are omnipresent intracellular organelles. Their number, size, and composition exhibit considerable heterogeneity within cells. Dysregulated lipid accumulation or depletion is not only a hallmark but ...

Clinical exercise professionals (CEPs) play a key role in supporting people with mental and physical health challenges. Yet access to services is inequitable, especially for ‘hard to reach’ or underserved populations...

Here we compare the efficacy of anti-obesity drugs alone or combined with exercise training on body weight and exercise capacity of obese patients. Randomized clinical trials that assessed the impact of any anti-obesity ...

Type 2 diabetes (T2D) is a complex and multifaceted condition clinically characterized by high blood glucose. The management of T2D requires a holistic approach, typically involving a combination of pharmacological inter...

Antipsychotic (AP) medications are used to treat schizophrenia and a number off-label conditions. Although effective in reducing psychoses these drugs increase the risk of developing cardiometabolic disease, and are one ...

Cardiac rehabilitation (CR), a multi-modal program centered around supervised exercise, is considered the standard of care for secondary cardiovascular disease (CVD) prevention. The primary goals of CR are managing CVD r...

Exercise training induces several skeletal muscle adaptations. Beta-guanidinopropionic acid (β-GPA) is a creatine analog that simulates the effect of exercise to induce mitochondrial biogenesis. However, the effects of ...