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Computational modeling of protein-protein interactions (PPIs) is a high priority because it is essential for understanding nearly all cellular functions and for addressing the limitations of time-consuming experimental m...

Abstract Chronic wounds represent a longstanding clinical problem due to impaired angiogenesis due to insufficient activation of vascular endothelial growth factor receptor 2 (VEGFR2). In this investigation, we used comp...

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in which immune dysregulation and metabolic remodeling are common features. Laminin subunit alpha 3 (LAMA3), a component of lamini...

The large-diameter ultra-long piles are commonly adopted for constructing ocean platform foundations. The pile-sliding phenomenon frequently takes place because of the great weight of both the piles and the hammer. Engin...

The rapid expansion of whole-genome sequencing (WGS) has highlighted the important contribution of noncoding variants to human disease, yet their pathogenic mechanisms remain difficult to resolve. Traditional statistical...

The P300 component of event-related potentials (ERPs) is widely used in the implementation of brain computer interfaces (BCI). In this context, one of the main issues to solve is the binary classification problem that en...

ABSTRACT Bio‐inspired optimisation methods have been widely applied to complex real‐world problems, particularly in low‐carbon power and energy systems, where optimisation tasks often involve high‐dimensional, co...

Background The long-term biological effects of low-level exposure to artificial sweeteners remain debated. We integrated computational toxicology and Mendelian randomization (MR) to explore potential biological responses...

Abstract Fewer than one thousand cataloged mechanistic annotations can be found in the open literature and databases. Here, we introduce MechFind, a computational tool that generates element and charge-balanced putative ...

We evaluate the performance of novel numerical methods for solving one-dimensional nonlinear fractional dispersive and dissipative evolution equations. The methods are based on affine combinations of time-splitting integ...

Abstract A Schiff base ligand L 1 was synthesized via the condensation reaction between from 2-hydroxy-1-naphthaldehyde and 4-methoxyaniline. This Schiff base was employed for the preparation of metal complexes of type [...

Abstract Background N6-methyladenosine ( $$m^{6}A$$ ) plays a crucial role in enriching RNA functional and genetic information. While deep learning has advanced $$m^{6}A$$ site identification, current state-of-the-art me...

Context. Astronomical environments are governed by a complex interplay of physical processes, including gravitational dynamics, radiative transfer, stellar evolution, chemistry, and hydrodynamics. These processes span a ...

Introduction. The performance reliability of electric vehicles (EVs) is an important factor in evaluating their suitability for widespread adoption. The reliability and lifespan of an EV depend on several critical factor...

Abstract Alkaline water electrolysis represents a promising pathway for green hydrogen production, yet comprehensive multi-physics simulation remains computationally prohibitive for practical design optimization. This st...

ABSTRACT This paper presents an event‐triggered pinning observer‐based control of unknown large‐scale interconnected systems under false data injection attacks using distributed noisy data without any system identi...

BackgroundIntegrated single-cell morpho-molecular analysis is vital for precision pathology, yet accurate nuclear instance segmentation from standard histopathology images remains challenging due to staining variability ...

Diels-Alder betweennitroalkenes derived from a sugar scaffold and cyclopentadiene were examined.Depending on chemical structure of nitroalkene and polarity of solvent used,the reaction proceeded via the formation of a ni...

En este artículo, se presenta parte de los resultados de un estudio sobre los posteos publicados por los diarios argentinos Clarín y La Nación en sus respectivas cuentas oficiales en Facebook, durante el período 2010...

Using specially designed low-temperature resonant column apparatus, change rules of dynamic shear moduli and damping ratio with negative temperature and their computational methods for three soils are investigated. Conce...

In this study, ordered mesoporous carbons CMK-3 were prepared by a nanocasting method using SBA-15 silica as template and sucrose as carbon source. The pure CMK-3 was modified with nickel by wet impregnation method and t...

ABSTRACT Transformers have been widely applied to hyperspectral image classification, leveraging their self‐attention mechanism for powerful global modelling. However, two key challenges remain as follows: excessive me...

Foothold selection for hexapod robots in complex terrain presents a significant challenge, demanding both high computational efficiency and robust adaptability. To address this issue, this paper introduces a foothold sel...

Abstract Intertidal macrobenthos are vital bioindicators of coastal ecosystem health due to their ecological roles, limited mobility, and sensitivity to environmental disturbances. However, traditional field‐based moni...