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The prediction and design of photonic features have traditionally been guided by theory-driven computational methods, spanning a wide range of direct solvers and optimization techniques. Motivated by enormous advances in...

The complement system is a blood-based immune network that plays a crucial role in fighting infection and maintaining immune homeostasis. The membrane attack complex (MAC) is a pore assembled from complement proteins tha...

With the advancement of personalized cancer immunotherapies, new tools are needed to identify tumor antigens and evaluate T-cell responses in model systems, specifically those that exhibit clinically relevant tumor progr...

Abstract Background Optimization of biotechnological processes is traditionally limited by time-consuming trial-and-error approaches and the complexity of simultaneously optimizing multiple, often conflicting objectives....

Abstract Access to large, diverse biomedical datasets is critical for advancing medical research, yet privacy regulations severely restrict data sharing. We present an end-to-end framework for privacy-preserving health d...

Although vaccination remains one of the most impactful interventions in contemporary public health, with consistent and widely documented reductions in morbidity and mortality, the traditional empirical development of va...

Introduction and aims: Oral and maxillofacial surgery (OMFS) produces complex clinical data, while artificial intelligence (AI) applications in this field remain limited despite great potential. This study aimed to map t...

BackgroundPrimary atopic disorders (PADs) are monogenic inborn errors of immunity marked by severe allergic disease. Heterozygous gain-of-function (GOF) variants in STAT6 have recently been recognized as a PAD associated...

Introduction: The identification of chemical compounds that interfere with SARS-CoV-2 replication continues to be a priority in several academic and pharmaceutical laboratories. Computational tools and approaches have th...

Abstract BackgroundDepression affects more than 300 million people worldwide and is a leading contributor to the global disease burden. Traditional diagnostic methods, such as structured clinical interviews, ...

"This work describes the use of entomological studies combined with in silico models (computer simulations derived from numerical models) to assess the efficacy of a novel device for controlled release of spatial repel...

La creciente urbanización e industrialización de la sociedad, sumado a una disponibilidad finita de recursos naturales, vuelve primordial hallar soluciones sustentables y eficientes que permitan la valorización de los...

En los últimos años, se ha desarrollado un gran interés por la producción de polímeros denominados funcionales o specialties. Los mismos se destacan por poseer algunas propiedades particulares que dan lugar a aplica...

Tesis de Doctorado El bloqueo de los puntos de control como CTLA-4 y PD-1/PD-L1 ha demostrado la actividad de efectores inmunes antitumorales, por lo que ha aumentado el interés en el desarrollo de inmunoterapias contra...