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ABSTRACT Background and Aims The immediate and long‐term effects of COVID‐19 pandemic on the children go beyond just being a viral infection. A child's mental health and psychological issues like irritability, anxiet...

Guangjian Wang,1,* Zhimao Li,2,* Xinyue Zhao,1 Xiaoru Wang,3 Hui Lian,1 Yecheng Liu2 1Department of Health Care, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Uni...

Abstract B and T lymphocyte attenuator (BTLA) and herpes virus entry mediator (HVEM) are emerging immune checkpoint molecules implicated in immune dysregulation during critical illness. We investigated the prognostic rel...

ObjectiveThe study aimed to assess the effects of resting energy expenditure (REE) on critically ill individuals requiring mechanical ventilation with different degrees of sedation.DesignA prospective self-controlled stu...

Having a brother or sister with mental illness (MI) has a profound effect on well-siblings’ health, quality of life, and relationships, and there is relatively little knowledge about their needs for information and sup...

Abstract Background Mortality prediction in critically ill patients is commonly performed with scoring systems such as SOFA and APACHE II. The arterial-to-end-tidal carbon dioxide gradient [P(a–et)CO₂], which can be ...

Sepsis remains one of the most complex and lethal syndromes in pediatric critical care, driven by dysregulated and heterogeneous host responses to infection. Despite decades of biomarker research, few biomarkers have bee...

Extensive burns are associated with numerous severe complications. While paralytic ileus is relatively common, the co-occurrence of acute pancreatitis (AP) is rare, clinically insidious, and highly fatal. Diagnosis is pa...

Abstract Food safety is a critical public health and economic issue in Afghanistan, where regulatory frameworks are evolving in response to complex political, social, and infrastructural challenges. This study examines t...

Extreme heat is a significant direct health threat from climate change, with rising temperatures and frequent heatwaves increasingly stressing communities and health services across Africa. High baseline temperatures, wi...

Increasing climate risks may influence the behavioral decisions of microeconomic entities, including household consumption choices. Based on the data of the China Household Finance Survey in 2019, this study empirically ...

BackgroundAcute respiratory distress syndrome (ARDS) secondary to severe acute pancreatitis (SAP) is associated with high mortality; however, dependable biomarkers for early risk assessment remain scarce. The lactate-to-...

Abstract Background Crush syndrome (consisting of hyperkalemia, acidosis, hypocalcemia, and acute kidney injury), is the second-most common cause of death in earthquakes, and a frequent cause of critical illness after bu...

Highly pathogenic avian influenza A (H5N1) remains a major zoonotic threat, yet human infections continue to display striking heterogeneity in clinical severity. We report a fatal case of H5N1 pneumonia in an adult patie...

Acute kidney injury (AKI) is a frequent complication affecting many hospitalized patients and is associated with increased morbidity and mortality. AKI seldom occurs as isolated organ failure; much more often it emerges ...

Abstract Nontraumatic adrenal hemorrhage (NTAH) has been associated with stress‐induced catecholamines release in underlying conditions such as sepsis and recent surgery in humans. It can lead to primary hypoadrenocort...

Abstract Background Thiamine (vitamin B1), a cofactor in energy metabolism and antioxidant pathways, may mitigate mitochondrial dysfunction in critical illnesses. However, its association with outcomes in acute respirato...

Bakgrunn: Tidligere intensivpasienter, og spesielt de som har vært sederte, kan ha økt risiko for å oppleve psykiske stressfaktorer som hukommelsestap og tilbakevendende minner, vrangforestillinger og/eller hallusinas...

Hoyeraal-Hreidarsson syndrome (HHS) represents the most severe form of dyskeratosis congenita (DC), a telomere biology disorder caused by pathogenic variants in genes involved in telomere maintenance. DKC1 encodes dysker...

Objective: The Arbovirus known as dengue belongs to the Flaviviridae class. Asymptomatic to severe illnesses (dengue haemorrhagic fever/dengue shock syndrome) are the clinical spectrum of its expression. Despite the fact...

Background: The period between 6 and 24 months represents a critical window for child growth, during which vulnerability to acute illness is high. Acute illness may disrupt normal growth trajectories; however, evidence o...

Abstract Treatment decisions in cancer care can be life-critical and significantly affect self-determination concerns. Therefore, it is of great importance that the decision-making process is set up in the interest and s...

Abstract Background Viral and infectious illnesses can exert profound and enduring effects on population health and well-being. In the aftermath of SARS-CoV-2 infection, post-acute sequelae, collectively referred to as L...

Abstract Introduction Across the globe, traditional medicine, particularly herbal remedies, is a cornerstone of healthcare. While the medicinal uses of ferns are widely recognized globally, their therapeutic potential in...