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In glomerular diseases, the occurence of lymphoma is mostly observed in the form of both minimal change disease and Hodgkin’s lymphoma. The coocurrence of Membranous nephropathy and membranoproliferative glomerulonephr...

Abstract Objectives To evaluate the prevalence, associated factors, and prognostic performance of NIH activity index–defined interstitial inflammation (NIH-TII) and interstitial fibrosis and tubular atrophy (IFTA) in l...

Classic polyarteritis nodosa (cPAN) is a systemic necrotizing vasculitis of medium-sized muscular arteries. Glomerular involvement is not expected in the course of cPAN. Herein, we describe a case of cPAN with glomerular...

Henoch-Schönlein purpura (HSP) is a vasculitis characterized by purpuric rash, arthritis, nephritis and gastrointestinal symptoms and it is generally seen in children. We report here a case of crescentic HSP nephritis w...

Renal involvement in systemic lupus erythematosus is a frequent and serious complication that significantly increases morbidity and mortality. Despite all studies and usage of new drugs, treatment of lupus nephritis cont...

Abstract Background Lupus nephritis (LN) is driven by podocyte pyroptosis triggered by NLRP3 inflammasome activation, yet the dual regulatory mechanisms—transcriptional control by the AP-1 complex (c-JUN/c-FOS heterodi...

Epidemiologies of nephropathies differ in different geographical and developmental areas. In order to determine the region’s adult nephropathy profile, consecutive renal biopsies performed between January 1997 and Dece...

Familial Mediterranean Fever (FMF) is an inflammatory autosomal recessive disease characterized by serosal and synovial involvement. Although secondary amyloidosis is the most common of the renal diseases observed with F...

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multisystem involvement. The renal involvement of SLE may present with hematuria , proteinuria or acute kidney dysfunction. It is well establis...

Posterior reversible encephalopathy syndrome (PRES) is characterised with neurological symptoms and typical radiological appearances. Hypertension is the most common cause of PRES. Systemic lupus erythematosus is a rare ...

Sarcoidosis is chronic multisystem granulomatous disease. It can rarely cause renal structural and functional damage. Renal impairment is mostly due to the calcium metabolism and associated with hypercalciuria, nephrolit...

Obinutuzumab is a humanized type II anti-CD20 monoclonal antibody with enhanced antibody-dependent cellular cytotoxicity. It is widely used in B-cell malignancies and is increasingly being explored in autoimmune diseases...

Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease with a high incidence of renal involvement during its course contributing to disease morbidity and mortality. All compartments of the kidney may be affe...

IgA nephritis is known as the most common glomerulonephritis and a disease with good prognosis. Acute renal failure, nephrotic syndrome and malignant hypertension can be seen less than 10% of patients with IgA nephritis....

Background Lupus nephritis (LN) is a leading cause of mortality in patients with systemic lupus erythematosus (SLE), and the accurate classification of renal pathological subtypes is crucial for reducing mortality rates ...

Systemic lupus erythematosus (SLE) is a chronic, occasionally life-threatening, multisystem disorder, and renal involvement is one of the most common and most serious complications of SLE. Among the various histological ...

Renal involvement is the cause of major mortality and morbidity of systemic lupus erythematosus (SLE) disease. Although regimes including pulse cyclophosphamide and corticosteroid are the most effective treatment modalit...

Abstract Background Lupus nephritis (LN) is a common and severe manifestation of systemic lupus erythematosus (SLE). We sought to evaluate treatment patterns, treat-to-target state attainment, and outcomes of patients wi...

Tubulointerstitial nephritis and uveitis syndrome is characterized by a combination of acute tubulointerstitial nephritis and uveitis. This syndrome is an uncommon cause of acute tubulointerstitial nephritis and is an ex...

Abstract Background The coexistence of renal artery stenosis (RAS) and acute tubulointerstitial nephritis (ATIN) is exceptionally rare. While imaging studies are essential for diagnosing RAS, noninvasive tests such as re...

Systemic Lupus Erythematosus (SLE) is a prevalent disease that shows all the characteristics of an autoimmune pathology. The developments in the pathogenic factors in SLE provide new insights to the treatment of SLE and ...

C1q deficiency is an inheritable immune disorder attributed to biallelic pathogenic mutations in C1q genes (C1QA, C1QB, or C1QC). Patients with C1q deficiency demonstrate increased susceptibility to severe infections and...

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Nonsteroidal anti-inflammatory drugs and paracetamol (acetaminophen) which are analgesic-antipyretic drugs are thought to be safe and are most commonly used in children to control pain and fever. We retrospectively an...