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Artificial pancreas (AP) algorithms can be divided into single-hormone (SH) and dual-hormone (DH). SH algorithms regulate glycemia using insulin as their control input. On the other hand, DH algorithms also use glucagon ...

"The first clinical trials using an Artificial Pancreas (AP) in Latin America have been defined in 2 stages. The first stage was carried out in November 2016 with the UVA controller (developed by the Center for Diabetes ...

"Background: Emerging therapies such as closed-loop (CL) glucose control, also known as artificial pancreas (AP) systems, have shown significant improvement in type 1 diabetes mellitus (T1DM) management. However, demandi...

"The first two studies of an artificial pancreas (AP) system carried out in Latin America took place in 2016 (phase 1) and 2017 (phase 2). They evaluated a hybrid algorithm from the University of Virginia (UVA) and the a...

"The purpose of this work is to compute a linear parameter-varying (LPV) model set that describes the insulin-glucose dynamics in type 1 diabetes (T1D). This set includes a nominal LPV model and dynamic uncertainty and i...

OBJECTIVE: The aim of our study was to compare the efficacy and safety of pancreas transplantation concomitant with renal transplantation (SPKT) or following renal transplantation (PAKT) and the exocrine anastomosis meth...

Serine proteases have wide application in leather, food, meat and soap powder industries, among others. There are a lot of methodologies to obtain them in large quantities but most of them are expensive or contaminating....

Objective: To develop an artificial intelligence (AI) driven plan tradeoff decision making assistant for radiation oncologists. Methods: A user interface (UI) was developed to integrate the assistant with the treatment p...

BackgroundSolid pseudopapillary tumors (SPTs) of the pancreas are rare, low-grade malignancies that generally have favorable outcomes when diagnosed at an early stage and can be resected. However, treatment options for p...

Background Renal replacement therapies can be life‐saving for dogs with severe acute kidney injury (AKI), however, comorbidities including pancreatitis might affect outcome. Hypothesis/Objectives To investigate the pre...

The adsorption of commercial trypsin (Try) onto epichlorohydrin cross-linked alginate–guar gum matrix has been studied at equilibrium in batch and in fixed bed column. Experiments were conducted to study the effect of ...

Acute pancreatitis (AP) urgently requires new therapeutic strategies. Here, we developed a maltose-alginate synbiotic microcapsule (AM-AR113) for intestinal delivery of Lactiplantibacillus plantarum AR113 and evaluated i...

OBJECTIVE: Oxidative stress is responsible for some important complications of diabetes mellitus. Zofenopril, which has an antioxidant effect, may decrease the oxidative stress of the diabetic microenvironment. The aim o...

"En los últimos años se ha incrementado el número de investigaciones orientadas al desarrollo de un Páncreas Articial (AP) para la regulación automática de glucosa en pacientes con Diabetes Mellitus Tipo 1 (T1DM). ...

The purpose of this article is to present a non-hybrid fully closed-loop controller for the Artificial Pancreas (AP) problem focused on long-term clinical trials and home-use applications. It includes physical activity (...

"In this work, a low-order model designed for glucose regulation in Type 1 Diabetes Mellitus (T1DM) is obtained from the UVA/Padova metabolic simulator. It captures not only the nonlinear behavior of the glucose-insul...

El objetivo de nuestro trabajo fue comparar la evolución del páncreas endocrino durante la vida de dos cepas murinas, una normal (Sprague Dawley) y una diabética espontánea (eSMT) a través del estudio de diferentes ...

A pesar de que la ozonoterapia se ha utilizado con éxito en la terapia con efectos beneficiosos, se han realizado pocos estudios bioquímicos o farmacodinámicos dirigidos al estudio de su mecanismo de acción. Hemos de...

El objetivo general de esta tesis fue estudiar la regulación ontogénica y alimentaria de la secreción de insulina y de la replicación y neoformación de células B pancreáticas en el Syrian golden hamster. Sus obje...

El objetivo de la tesis es: a) profundizar el conocimiento de los mecanismos que regulan la expresión génica y proteica de la HQ y GQ y su actividad, en islotes pancreáticos de ratas Wistar normales y con IR inducida ...

"Keeping the blood glucose levels within the safe range during meals and exercise still represents a major hurdle not only for patients with type 1 diabetes (T1D), but also for Artificial Pancreas (AP) systems. One of th...

Objective: In contrast to penetrating trauma, blunt pancreatic trauma poses numerous challenges for treating surgeons, mainly due to the different clinical manifestations. Materials and methods: This is a retrospective o...

"En este trabajo se presenta la experiencia argentina en el problema de regulación de los niveles de glucosa en sangre para pacientes con Diabetes Mellitus Tipo 1 (insulino-dependientes), denominado Páncreas Artificial...

The peroxisome proliferator-activated receptors (PPARs), including PPAR-α, PPAR-β/δ, and PPAR-γ, are nuclear receptors that play critical roles in regulating metabolism and inflammation. While PPARs have been extensi...