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Cardiovascular, respiratory, and related disorders (CVRDs) are the leading causes of adult death worldwide, and substantial inequalities in care of patients with CVRDs exist between countries of high income and countries...

It is reeported in the literatures that the incidence of sleep disorders is high (50-83 %) in hemodialysis patients, possibly resulting in poorer quality of life. This study is designed and carried out in order to evalua...

The aim of this work is to demonstrate and analyze a clinical case of catatonic stupor as a consequence of the complex effect of the infectious process, namely systemic inflammation and direct neurotoxicity of the SARS-C...

Background People with schizophrenia have a high premature mortality risk. Obesity is a key potential underlying risk factor that is relatively unevaluated to date.Aims In this study, we investigated the associations of ...

Background and Literature ReviewHypereosinophilic syndrome (HES) is a rare, heterogeneous group of disorders defined by persistent hypereosinophilia (>1,500 cells/µL) with eosinophil-mediated end-organ damage. Its estim...

Background and AimsAcquired immunodeficiency in patients with hematological oncology is a serious and common complication, significantly impacting prognosis and quality of life. High doses of cytostatic drugs and the mal...

The gut microbiota has co-evolved with its host and forms an essential component of the human body. It is acquired at birth and continues to develop alongside the host, preserving its diversity and stability throughout l...

Indoor air quality is a crucial factor that directly impacts worker safety and health (K3), where exposure to hazardous pollutants such as formaldehyde can trigger irritation, respiratory disorders, and long-term health ...

The Gulf Coast region of Louisiana hosts one of the highest concentrations of petrochemical industries in the United States, contributing substantially to national economic output while simultaneously posing severe envir...

Hoyeraal-Hreidarsson syndrome (HHS) represents the most severe form of dyskeratosis congenita (DC), a telomere biology disorder caused by pathogenic variants in genes involved in telomere maintenance. DKC1 encodes dysker...

Abstract Background Bronchoalveolar lavage (BAL) fluid cytology and culture are used to characterize respiratory diseases in dogs. Little is known about disorders associated with increased numbers of lymphocytes in BAL f...

LPS-responsive beige-like anchor protein (LRBA) deficiency is a primary immunodeficiency belonging to the spectrum of common variable immunodeficiency disorders, frequently associated with immune dysregulation, autoimmun...

Background Histologic features of pulmonary veno‐occlusive disease (PVOD) and pulmonary capillary hemangiomatosis (PCH) have been described in dogs but without a thorough clinical description. Objectives To report the ...

BackgroundThe toxicities associated with immune checkpoint inhibitors (ICIs) can affect nearly all organ systems. Although previous studies have examined specific types of immune-related adverse events (irAEs) associated...

Importance Tinnitus, affecting 10% to 15% of the global population, is a debilitating condition often linked to hearing loss and neurological disorders. While air pollution is a known risk factor for respiratory and card...

OBJECTIVE: Cadaveric organ donation is not at desired levels in our country. However, the number of patients on cadaveric kidney waiting lists is increasing. This situation also makes it difficult to follow cadaveric kid...

IntroductionRNU4ATAC-opathies are characterized by biallelic pathogenic variants and include three recognized phenotypes: autosomal recessive Roifman syndrome, microcephalic osteodysplastic primordial dwarfism (MOPD), an...

IntroductionThe ERCC2 gene, located on chromosome 19, is essential for transcription and DNA repair via its protein product, XPD. Mutations in ERCC2 cause disorders such as trichothiodystrophy-1, xeroderma pigmentosum, C...

Ethnopharmacological relevance This article presents the results of a study on wild plant pharmacopeia and medical ethnobotany of the Wichí people of the South American Gran Chaco region, where native forest still persi...

Abstract Background Belgium’s emergency services face several public health challenges, including increasing patient numbers and a shortage of medical staff. Against this backdrop, there is a risk that current organisa...

ObjectiveThis systematic review and meta-analysis aims to evaluate the effects of Tai Chi Chuan on the expression of pro-inflammatory genes IL-6, IL-1β, and TNF-α—downstream of the NF-κB pathway—in adults with chr...

Environmental justice communities across the United States continue to experience disproportionate exposure to industrial pollution, particularly in regions dominated by petrochemical infrastructure. The Alsen / St. Irma...

The pandemic of COVID-19 left profound global impacts on public health, economics, and social dynamics. Since its emergence, the virus has spread across 229 countries, infecting over 590 million individuals and causing 7...

IntroductionToll-like receptor 8 gain-of-function (TLR8 GOF) is a recently described inborn error of immunity caused by activating mutations in Tlr8. Pathogenic variants lead to constitutive signaling in myeloid cells an...