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ABSTRACT Platelets are crucial to the development of thrombosis and coagulation abnormalities in sepsis, but the mechanisms by which they contribute to these pathological processes are not fully understood. Here, we iden...

Abstract Background Patients with AIDS Suffering from sepsis secondary to pulmonary infections admitted to intensive care units (ICUs) carry a high burden of morbidity and mortality. Therefore, rapid identification and t...

BackgroundSevere fungal pneumonia with sepsis carries high mortality. Early and accurate prognosis is essential for improving outcomes. We developed and validated a nomogram based on immune-inflammation-nutrition indicat...

Introduction: Neonatal sepsis remains a major cause of neonatal morbidity and mortality worldwide, particularly in resource-limited settings where advanced diagnostic facilities are not readily available. The condition o...

Objective: To describe circadian disruptions in septic patients and their relation to clinical outcome. Methods: In this work we performed an individual analysis of hemodynamic variables (cardiac frequency and mean blood...

ObjectiveTo explore the effects of different serum potassium levels on the 28-day prognosis of elderly patients with sepsis. MethodsA retrospective analysis was conducted on the clinical data and laboratory indicators wi...

Abstract Background Pulmonary injury in sepsis often develops into acute respiratory distress syndrome (ARDS), in which the polarization state of alveolar macrophages (AMs) is a central pathogenic factor. Bone marrow mes...

Extrauterine leiomyomas are rare, benign, and may arise in any anatomic sites. Their unusual growth pattern may even mimic malignancy and can result in a clinical dilemma. Occasionally, uterine leiomyomas become adherent...

Abstract Haematological malignancies (HMs) are characterized by profound immune dysregulation, which increases susceptibility to sepsis. This dysregulation arises from the underlying disease and may be exacerbated by tre...

El objetivo de esta reflexión es resaltar la importancia de la influencia del inmunometabolismo macrofágico y su respuesta dirigida a la sepsis humana como un enfoque terapéutico en el futuro cercano. La sepsis es un ...

Abstract Background Pediatric sepsis remains a leading cause of global mortality, necessitating early and accurate risk stratification. Traditional scoring systems often fail to capture the rapid, non-linear progression ...

Abstract Background Recent studies highlight the critical role of gut microbiota in sepsis pathogenesis and its potential link to neurological disorders, particularly sepsis-associated encephalopathy (SAE). However, the ...

Neonatal sepsis has remained a foremost cause of morbidity and mortality globally, specifically in low- and middle-income countries. The neonatal period, which spans the first 28 days of life, has the highest lifetime ri...

Sepsis is a life-threatening syndrome defined by organ dysfunction arising from a dysregulated host response to infection. In its more severe forms, it may progress to multiple organ failure and is associated with a subs...

Abstract Background Rapid and accurate markers to aid diagnosis of sepsis are needed in neonatal foals. The CBC variable red blood cell distribution width (RDW) to platelet ratio (RPR) is associated with inflammatory res...

A sepse é uma das principais causas de morte materna, estando relacionada a infecções de origem obstétrica (aborto infectado, corioamnionite, infecção puerperal) ou não-obstétricas (resultando de infecções que ...

Abstract Background Prognostic assessment in sepsis involves evaluating the dynamic progression of organ dysfunction and the inflammatory response. This study compared the predictive value of serially measured serum HMGB...

Shenfu Injection (SFI) is a standardized botanical drug derived from two Chinese medicinal herbs Panax ginseng C.A.Mey. and Aconitum carmichaelii Debeaux. SFI is historically used for “restoring yang and reversing coll...

BackgroundSepsis-induced cardiomyopathy (SCM) is a common complication in patients with sepsis. Although the prognostic nutritional index (PNI) is less comprehensive than other assessment methods, it remains a readily ac...

Objective This study aimed to explore the influence of the angiotensin-(1–7)/Mas receptor and angiotensin II/angiotensin II type 1 receptor pathways on pyroptosis during sepsis and their subsequent effects on cognitive...

Abstract Background Antimicrobial treatment protocols for foals with sepsis that do not improve clinically often are adjusted based on bacteriological and antimicrobial susceptibility testing results from samples collect...

BackgroundPredicting enterocutaneous fistula (ECF)–associated sepsis and mortality poses significant challenges in digital health care due to the disease’s complexity and heterogeneous clinical manifestations. Curren...

ABSTRACT Background The glutaraldehyde test (GT) is used as a point‐of‐care test to detect inflammatory disease in cattle. Objectives Describe the relationship between GT and fibrinogen as well as GT and total protei...

Sepsis remains one of the most complex and lethal syndromes in pediatric critical care, driven by dysregulated and heterogeneous host responses to infection. Despite decades of biomarker research, few biomarkers have bee...