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A classification model based on G protein-coupled estrogen receptor binding affinity: development and validation

ISSN: 10048456 · Editor / fuente: The Editorial Office of Chinese Journal of Food Hygiene

147

contenidos disponibles

Validation of the Italian version of the Short Mood and Feelings Questionnaire (SMFQ) in a sample of adolescents
Artículo
Acceso abierto Artículo DOAJ
Luisa Almerico et al · BMC · 2026 · ISSN 1824-7288
Abstract Background Depression is a prevalent and often persistent mental disorder, with onset frequently occurring during adolescence and associated with serious long-term consequences. Consequently, the availability of...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
Open Access
Validation of LILR antibody specificities and development of LILRA3-specific antibodies
Artículo
Acceso abierto Artículo DOAJ
Hiromu Tanimoto et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Leukocyte immunoglobulin (Ig)-like receptors (LILRs) constitute a family of 11 structurally related receptors predominantly expressed on immune cells. Despite their functional diversity, LILRs show a high degree of seque...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Development and Internal Validation of a Prognostic Model for Delayed Ambulation Recovery After Major Abdominal Surgery in Northwest Ethiopia. A Prospective Multicenter Study
Artículo
Acceso abierto Artículo DOAJ
Mulualem Endeshaw Zeleke et al · Springer · 2026 · ISSN 2210-6014
Abstract Background Delayed ambulation recovery following major abdominal surgery presents a significant prognostic challenge, contributes to increased morbidity, mortality, and prolonged hospital stay. Despite recommend...
LCC LCC:Public aspects of medicineIdioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
Open Access
Development and external validation of a musculoskeletal ultrasound-based prediction model for limited shoulder range of motion in nursing staff with neck–shoulder pain: a cross-sectional study
Artículo
Acceso abierto Artículo DOAJ
Rui Zhao et al · Frontiers Media S.A · 2026 · ISSN 2296-2565
BackgroundNurses with neck–shoulder pain are at high risk of developing limited shoulder range of motion (ROM), but early prediction tools are lacking. This study aimed to identify risk factors using clinical data and ...
LCC LCC:Public aspects of medicineIdioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
Open Access
Development of an online prediction tool for immunotherapy-related adverse events in patients with advanced NSCLC based on machine learning and temporal validation
Artículo
Material complementario disponible Artículo DOAJ
Ling-Chun Cao et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
ObjectiveDespite the widespread use of immune checkpoint inhibitors (ICIs) improving survival outcomes in non-small cell lung cancer (NSCLC) patients, immune-related adverse events (irAEs) triggered by ICIs have become a...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Next generation validation for next generation risk assessment
Artículo
Acceso abierto Artículo DOAJ
Karolina Kopańska et al · Frontiers Media S.A · 2026 · ISSN 2673-3080
Next generation risk assessment (NGRA) demands a fundamental transformation in how toxicological test methods are validated. Traditional validation approaches, designed for animal tests and mainly for simple in vitro met...
LCC TENDOlRveGljb2xvZ3kuIFBvaXNvbnM~Idioma eng
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Open Access
Achieving “textbook outcome” after hepatectomy for hepatocellular carcinoma in the era of enhanced recovery: development and validation of a clinical nomogram
Artículo
Acceso abierto Artículo DOAJ
Chang Cheng et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundTraditional perioperative metrics such as complication rates and length of stay (LOS) are fragmented and fail to capture the “ideal” recovery trajectory. “Textbook outcome” (TO) has emerged as a composi...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Open Access
Construction and validation of a prediction model for in-stent restenosis following coronary stent implantation during dual antiplatelet therapy
Artículo
Material complementario disponible Artículo DOAJ
Zhuoyi Zhang et al · Frontiers Media S.A · 2026 · ISSN 2297-055X
ObjectivesIn-stent restenosis (ISR) is a serious complication that occurs after a percutaneous coronary intervention (PCI). This study aims to integrate thromboelastography (TEG) parameters, coagulation function, and cli...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Convergent Validation of Trait Induction in LLMs
Artículo
Acceso abierto Artículo DOAJ
Yasin Edin et al · Hogrefe Publishing Group · 2026 · ISSN 2698-1866
Abstract: This study investigates an approach to test a key requirement for using large language models (LLMs) to simulate valid data sets of item-responses, namely the effect of trait induction on another related constr...
LCC TENDOlBzeWNob2xvZ3k~Idioma eng
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Open Access
Decoding FGFR inhibitor sensitivity in cholangiocarcinoma with interpretable machine learning and cross-platform pharmacogenomic validation
Artículo
Material complementario disponible Artículo DOAJ
Yading Xie et al · Frontiers Media S.A · 2026 · ISSN 1663-9812
BackgroundFibroblast growth factor receptor (FGFR) inhibitors (FGFRis) benefit selected cholangiocarcinoma (CHOL) patients, yet responses remain heterogeneous and are not fully explained by canonical FGFR alterations. Cl...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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Design and implementation of a low-cost IoT-enabled dual-axis photovoltaic tracking system with experimental and simulation-based validation
Artículo
Material complementario disponible Artículo DOAJ
Md. Nazmul Howlader et al · SpringerOpen · 2026 · ISSN 2314-7172
Abstract Photovoltaic (PV) systems have become one of the most important solutions to sustainable energy production due to the growing demand of renewable energy and the necessity to harness energy in the most efficient ...
LCC LCC:Electrical engineering. Electronics. Nuclear engineering; TENDOkluZm9ybWF0aW9uIHRlY2hub2xvZ3k~Idioma eng
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Development and External Validation of a Machine Learning Model for Automated Feedback Quality Assessment in Chinese Anesthesiology Residency Training
Artículo
Material complementario disponible Artículo DOAJ
Yao L et al · Dove Medical Press · 2026 · ISSN 1179-7258
Lifeng Yao, Yijun Chen, Jing Shen, Junge Zhang, Yiwei Zhang, Guojin Liang, Yiqin Ji Department of Anesthesiology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, People’s Republic of ChinaCorrespo...
LCC TENDOlNwZWNpYWwgYXNwZWN0cyBvZiBlZHVjYXRpb24~; TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Development and internal validation of a frailty prediction model in adults aged ≥ 45 years with obesity: evidence from the China Health and Retirement Longitudinal Study (CHARLS)
Artículo
Material complementario disponible Artículo DOAJ
Youfu Wang et al · BMC · 2026 · ISSN 1471-2458
Abstract Objective Given the increased risk of frailty among middle-aged and older adults with obesity, we aimed to develop and validate a predictive model for incident frailty among adults aged ≥ 45 years with obe...
LCC LCC:Public aspects of medicineIdioma eng
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Development and internal validation of a machine learning model for predicting intracranial infection after spontaneous intracerebral hemorrhage: a two-center retrospective study
Artículo
Material complementario disponible Artículo DOAJ
Yizhao Lin et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
BackgroundIntracranial infection (ICI) is a serious complication following spontaneous intracerebral hemorrhage (ICH) and is associated with prolonged intensive care, increased morbidity, and poor functional outcomes. Ea...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Development and validation of a 28-day mortality risk prediction model for patients with AIDS suffering from sepsis secondary to pulmonary infections in the ICU
Artículo
Acceso abierto Artículo DOAJ
Qihui Ran et al · BMC · 2026 · ISSN 1471-2334
Abstract Background Patients with AIDS Suffering from sepsis secondary to pulmonary infections admitted to intensive care units (ICUs) carry a high burden of morbidity and mortality. Therefore, rapid identification and t...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Open Access
Development and validation of a deep learning-based automatic detection and classification model for femoral neck fractures using hip imaging: a retrospective multicenter diagnostic study
Artículo
Material complementario disponible Artículo DOAJ
Xueyang Han et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
Conventional Garden classification of femoral-neck fractures relies on radiography or CT, but image quality variations, indistinct fracture lines, and inter-observer differences often cause misclassification—especially...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Development and validation of a nomogram based on immune-inflammation-nutrition indictors for predicting 28-day mortality in sepsis patients with severe fungal pneumonia
Artículo
Acceso abierto Artículo DOAJ
Gongliang Du et al · Frontiers Media S.A · 2026 · ISSN 2235-2988
BackgroundSevere fungal pneumonia with sepsis carries high mortality. Early and accurate prognosis is essential for improving outcomes. We developed and validated a nomogram based on immune-inflammation-nutrition indicat...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Open Access
Development and validation of a risk prediction model for in-hospital mortality among patients with acute myocardial infarction complicated by ventricular arrhythmia
Artículo
Material complementario disponible Artículo DOAJ
Jiao-yu Cao et al · BMC · 2026 · ISSN 1471-2261
Abstract Background With the widespread adoption of percutaneous coronary intervention (PCI), patients experiencing acute myocardial infarction (AMI) complicated by ventricular arrhythmia (VA) continue to encounter a sig...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Development and validation of a risk stratification tool for predicting COPD exacerbations in patients without prior exacerbation history
Artículo
Material complementario disponible Artículo DOAJ
Chau-Chyun Sheu et al · BMJ Publishing Group · 2026 · ISSN 2052-4439
Background Acute exacerbations (AEs) drive disease progression and healthcare burden in chronic obstructive pulmonary disease (COPD). Although prior AE history is the strongest predictor of future events, it cannot guide...
LCC LCC:Medicine; TENDOkRpc2Vhc2VzIG9mIHRoZSByZXNwaXJhdG9yeSBzeXN0ZW0~Idioma eng
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Development and validation of an explainable machine learning model for predicting interstitial fibrosis and tubular atrophy in biopsy-confirmed diabetic nephropathy
Artículo
Material complementario disponible Artículo DOAJ
Huifang Wang et al · Frontiers Media S.A · 2026 · ISSN 1664-2392
BackgroundInterstitial fibrosis and tubular atrophy (IFTA) are key pathological features of chronic kidney damage and progression in diabetic nephropathy (DN). Early identification of patients at higher risk of IFTA may ...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Evaluation of coronary heart disease risk prediction based on simple physical examination parameters by machine learning model: a retrospective cohort model development and validation study
Artículo
Material complementario disponible Artículo DOAJ
Hui Xiong et al · Frontiers Media S.A · 2026 · ISSN 2297-055X
BackgroundTo develop and externally validate a coronary heart disease (CHD) risk model from routine clinical indicators and identify key predictors.MethodsThe Framingham Heart Study cohort (n = 4,240) was used. Missi...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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First molecular characterization and species validation of Toxocara alienata (Rudolphi 1819) (Nematoda: Ascarididae), from a crab-eating raccoon (Procyon cancrivorus)
Artículo
Acceso abierto Artículo CONICET Digital
do Carmo, Gustavo Macêdo et al · Elsevier Ireland · 2026 · ISSN 1383-5769
Toxocara alienata infects racoons and wild pigs in South America and its taxonomy is important to distinguish thespecies from closely related zoonotic congeners, such as T. canis. This study provides the first genetic ch...
Idioma eng
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Open Access
IEI Subphenotype Recognition Using Unsupervised Machine Learning on a National IEI Cohort with Clinical Validation
Artículo
Material complementario disponible Artículo DOAJ
Alexandra Martinson et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Inborn errors of immunity (IEI) are increasing in number, and prompt recognition and diagnosis remain a challenge for clinicians. Use of machine learning (ML) for clinical pattern recognition is promising but has been li...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Identification and validation of hub genes involved in papillary thyroid carcinoma progression
Artículo
Material complementario disponible Artículo DOAJ
Zunera Khalid et al · BMC · 2026 · ISSN 1471-2407
Abstract Papillary Thyroid Cancer (PTC) is one of the most prevalent endocrine malignancies, and its incidence rate has almost tripled over the past three decades. The current study aimed to identify gene alterations and...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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