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The objective of the present investigation was to develop and evaluate microemulsion-based hydrogel (MBH) for the topical delivery of sinomenium. The solubility of sinomenium in oils and surfactants was evaluated to iden...

A new spectrophotometric method employing a micellar medium is proposed for the determination of paracetamol in pharmaceuticals. The method is based on the acid hydrolysis of paracetamol to p-aminophenol (PAP), which und...

The present study aims at developing synthesized (PVA-co-PAA)/NaCl normal hydrogel(H), hydrogel microspheres(HM) and comparing the antihypertensive activity of Diltiazem hydrochloride(DL) from two formulations. The hydro...

The objective of the present study was to minimize the unwanted toxic effects of antihypertensive drug diltiazem hydrochloride (DTZ) by kinetic control of drug release from microparticles using chemically modified locust...

The synthetic polymers and their combinations were employed to retard the release of nimesulide from microcapsules. Microcapsules were prepared in different ratios of Eudragit RL 100 and hydroxy propyl methyl cellulose (...

The project was aimed to develop floating microcapsules (FMs) using combination of a hydrophobic (ethyl cellulose, EC) and hydrophilic polymer (hydroxy propyl methyl cellulose, HPMC), and to evaluate them. An easy and no...

The present investigation aims at feasibility assessment of ethyl cellulose (EC) and polyvinylpyrrolidone (PVP) based ondansetron hydrochloride matrix type transdermal systems. The effects of polymeric concentration, its...

The release behavior of salicylic acid and the bioadhesion properties of crosslinked polyacid hydrophobic-gel disks, containing methyl methacrylate-co-methacrylic acid, were evaluated in simulated fluids. In gastric flui...

Biodegradable microspheres of Tramadol Hydrochloride (TmH) were developed using simple phase separation technique. Poly lactide-co-glycolide (PLGA) was employed as a release controlling polymer. Simple phase separation...

The objective of the present study was to stabilize doxorubicin hydrochloride in sugar-phosphate amorphous mixtures at ambient temperature by drying it with vacuum foam drying. Finished products were evaluated for foam...

Hydroquinone (HQ) is a drug reported to possess manifold biological activities. HQ is highly unstable into various topical vehicles, presenting low topical bioavailability and a relevant level of toxicity. The Pluronic®...

"The aim of this project is to study the use of energy surplus from local renewable sources at isolated places in Argentina, to produce electrolytical hydrogen as clean fuel for electricity generation. Furthermore, the h...

Microglial-neuronal interactions are essential for brain physiopathology. In this framework, recent data have changed the concept of microglia from essentially macrophagic cells to crucial elements in maintaining neurona...

Se ensayaron cuatro lipasas microbianas con la intención de aumentar el contenido de los ácidos grasos poliinsaturados de la serie W3 (AGPI W3) en la fracción de glicéridos no hidrolizados después de la hidrólisis ...

Papaína (PA) y pepsina (PE) fueron utilizadas en la preparación de hidrolizados enzimáticos de la leche desnatada, solas o en asociación con una proteasa de Aspergillus oryzae (AO). Con el objetivo de emplear estos h...