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Implants prepared with polymer blends [poly (e-caprolactone)-poly(lactide), PCL-PLA] at different rates were developed from microspheres. Approximately 19% of dexamethasone acetate was encapsulated into the microsphere...

The aim of this study was to formulate ethyl cellulose (EC) microparticles for sustained release of nimesulide and study the effect of processing variables, drug to polymer ratio and also study the drug polymer compatibi...

The purpose of this study was to attain and characterize ternary complexes of simvastatin, β-cyclodextrin (βCD) and different polymers, and then select those that lead to a greater increase in drug solubility. The comp...

Polymeric and lipid nanocapsules suspensions of the natural compound curcumin were prepared in order to overcome limitations associated with its clinical applications, such as poor aqueous solubility and susceptibility t...

Free films were obtained by the combination of a polymer EudragitTM FS30D and oligosaccharides (alpha or gamma-CDs), by a casting process. The films were characterized by DSC, TGA, FTIR and SEM. The influence of composit...

The present investigation concerns the development of a floating matrix tablet, which after oral administration prolong the gastric residence time and increases bioavailability of drugs, which are predominantly absorbed ...

The aim of this study was to develop topical hydrogels containing diclofenac potassium (DP) at 1 % w/v concentration using conventional hydrophilic hydroxypropyl methyl cellulose (HPMC, 50cPs) and modified hydrophobic ...

This study introduced a novel phase separation technique for the microencapsulation of metoprolol tartrate as a model. Non-solvent addition coacervation technique was employed for the loading of drug into ethylcellulose,...

Transdermal drug delivery systems of venlafaxine hydrochloride were prepared by using combination of hydrophilic (HPMC E15) and hydrophobic (ERS100 and ERL 100) polymers in 1:5, 2:4, 3:3, 4:2, 5:1 ratios by solvent casti...