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Repaglinide is a potent second generation oral hypoglycaemic agent widely used in treatment of non insulin dependent diabetic mellitus. The objective of the present study was to develop sustained release microspheres of...

The effects of drying air inlet temperature (IT) and concentration of Aerosil® 200 (CA) on several properties of spray-dried Apeiba tibourbou extracts were investigated following a 32 full factorial design. Powder recov...

Cat's claw (Uncaria tomentosa (Willd) DC) is an alkaloid rich-liana from the Peruvian Amazon rainforest. Regarding several oxindole alkaloids from cat's claw bark, the isomerization induced by pH, temperature and solvent...

The present study evaluated novel polymer mixtures prepared by spray drying of an aqueous dispersion of moth bean starch with Carbopol 934P and HPMC K4M for to be used as platform for peroral mucoadhesive drug delivery...

Novel stable mucoadhesive chitosan microspheres were developed to explore the possibility of nasal delivery of L-dopa to avoid first pass metabolism and to improve therapeutic efficiency in treating the symptoms of parki...

Nanocapsule suspensions containing coenzyme Q10 were prepared by interfacial deposition. The nanocapsules showed characteristics compatible with dermal application: slightly acid pH, drug content close to 100%, particle ...