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Potyvirus diseases are one of the main challenges facing the production of yam (Dioscorea spp.). The objective of this study was to identify the potyviruses present in the Dioscorea spp. germplasm collection at Instituto...

Tamoxifen is a standard endocrine therapy for estrogen receptor positive breast cancer patients. Despite its success,development of resistance mechanisms is still a serious clinical problem. Deregulation of survival sign...

Parkinson’s disease (PD) is the second most common neurodegenerative disorder related with aging. The death of dopaminergic neurons triggered by oxidative stress and mitochondrial dysfunction is one pathognomonic chara...

The rodent Oligoryzomys longicaudatus (Bennett, 1832) (Rodentia, Cricetidae) inhabits southern forests of Argentina and Chile, a region severely affected by glaciations during the Pleistocene-Holocene periods. We evaluat...

We have investigated the reaction of peroxynitrite with carbon dioxide in aqueoussolution by means of combined quantum-classical (QM-MM) molecular dynamics simulations.In our QM-MM scheme, the reactant was modeled using ...

Forests play an important role in water and carbon cycles in semiarid regions such as the Mediterranean ecosystems. Previous research in the Chilean Mediterranean forests revealed a break point in 1980 in regional tree-r...

Polyphenol Oxidases (PPOs) catalyze the conversion of phenolic substrates to quinones, leading to the formation of dark-colored precipitates in fruits and vegetables. This process, known as enzymatic browning, is the cau...

To gain insight into the functional relationship between the nucleocapsid (NC) domains of the Gag polyproteins of feline and simian immunodeficiency viruses, FIV and SIV, respectively, we generated two FIV Gag chimeric p...

Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive. Using two different strategies t...

Metabolic dysfunction-associated steatohepatitis (MASH) is a major challenge in hepatology. Despite considerable progress in our understanding of MASH, the particular mechanisms underlying disease development and the var...

For each n∈N, we introduce the algebraic semantics for the minimum many-valued modal logic over the MV-chain with n elements. We prove that this quasivariety of algebras is generated by the complex algebras, obtaining ...

We have analyzed the DNA-binding properties of the complex formed by the Arabidopsis TALE homeodomain (HD) proteins STM and BLH3 in comparison with those of the individual proteins. In vitro DNA-binding assays indicated ...

Leishmaniasis is a parasitic disease caused by hemoflagellates of the genus Leishmania and is transmitted to humans by the bite of infected phlebotomine sandflies. Depending on the Leishmania species, the disease has dif...

In this work we show that global topological properties of co-occurrent word networks constructed from texts, seem to be the fingerprint of meaningful sentences. We observe that many statistical properties of these netwo...

In a recent study we found that crania from South Amerindian populations on each side of the Andes differ significantly in terms of craniofacial shape. Western populations formed one morphological group, distributed cont...

Sideroxylon obtusifolium (Humb. ex Roem. & Schult.) T.D. Penn. is a tree species belonging to the Sapotaceae family, whose black berries can be consumed fresh or as jam. It is widely distributed in Mexico, Belize, Costa ...

We report the emergency development and application of a robust serologic test to evaluate acute and convalescent antibody responses to SARS-CoV-2 in Argentina. The assays, COVIDAR IgG and IgM, which were produced and pr...

This paper attempts to design statistical models to forecast annual precipitation in the Neuquen and Limay river basins in the Comahue region of Argentina. These forecasts are especially useful as they are used to better...

The aim of this study is to investigate the folding reaction of human frataxin, whose deficiency causes the neurodegenerative disease Friedreich’s Ataxia (FRDA). The characterization of different conformational states ...

Infection by Brucella species in pregnant animals and humans is associated with an increased risk of abortion, preterm birth, and transmission of the infection to the offspring. The pathogen has a marked tropism for the ...

The immune system is an important modulator of learning, memory and neural plasticity. Interleukin 1β (IL-1β), a pro-inflammatory cytokine, significantly affects several cognitive processes. Previous studies by our gro...

We study the correlator of concentric circular Wilson loops for arbitrary radii, spatial and internal space separations. For real values of the parameters specifying the dual string configuration, a typical Gross-Ooguri ...

Ombrotrophic peat bogs from Tierra del Fuego are characteristically raised, dome-shaped, fed by precipitation, and nutrient-poor. Their landscape pattern consists of a Sphagnum magellanicum matrix encompassing pools with...