Buscar recursos académicos

Background: Intrahepatic cholangiocarcinoma (ICC) is an aggressive hepatobiliary malignancy characterized by a complex pathogenesis and poor prognosis. Telomere dysfunction and cellular senescence are involved in the pat...

Mitochondrial dysfunction is a convergent hallmark of biological aging and a mechanistically attractive target for gerotherapeutic development. Yet translation of mitochondria-focused interventions has been limited by pa...

Background: Periodontitis combined with orthodontic treatment creates a complex inflammatory and biomechanical microenvironment in gingival tissue, where macrophages play pivotal roles in tissue remodeling and immune reg...

Oral mucosal ageing represents a fundamental reprogramming of the tissue microenvironment, a dynamic process that underlies the functional decline and heightened disease susceptibility observed in the elderly. This revie...

ABSTRACT: Introduction and aims: To provide the research progress on the cGAS-STING signalling pathway and its related roles in various oral diseases. Methods: We reviewed the recent research on cGAS-STING in PubMed. Th...

Cognitive impairment is a growing public health concern associated with aging, neurodegenerative diseases, and chronic stress. Polygonatum sibiricum Red. (P. sibiricum, Huang Jing), a traditional Chinese medicinal herb, ...

Silicosis, caused by inhalation of crystalline silica (SiO2), remains a serious and persistent public health concern. Puerarin (Pue), a bioactive isoflavone derived from Pueraria lobata, is known for its anti-inflammator...