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BackgroundIntracranial infection (ICI) is a serious complication following spontaneous intracerebral hemorrhage (ICH) and is associated with prolonged intensive care, increased morbidity, and poor functional outcomes. Ea...

Timely access to public healthcare is fundamental human rights and a key measure of social equity. In Thailand, transportation barriers especially in rural and underserved areas continue to restrict equitable access to m...

BackgroundEarly detection of diabetic retinopathy (DR) remains challenging in primary care, where access to ophthalmic screening is limited. We developed and validated a prediction model using routinely collected health ...

Falls among older adults pose a major healthcare and social burden, making early identification of high-risk individuals essential for prevention. This study presents a portable, non-invasive AI-based wearable system tha...

BackgroundGlobal population aging is accelerating, and China faces a significant challenge with “aging before affluent.” The disabled older adults population in China is projected to reach 58 million by 2050. Early i...

BackgroundTo develop and externally validate a coronary heart disease (CHD) risk model from routine clinical indicators and identify key predictors.MethodsThe Framingham Heart Study cohort (n = 4,240) was used. Missi...

BackgroundThere is limited understanding regarding the factors that predict recreational therapy engagement among veterans in long-term care facilities. We aimed to develop and validate machine learning models to predict...

Atherosclerosis, driven by elevated cholesterol levels, remains a major risk factor for cardiovascular disease. 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR), the rate-limiting enzyme involved in cholesterol bio...

IntroductionEarly identification of adolescents at risk for substance use is critical for timely intervention. However, standard screening tools like CRAFFT (Car, Relax, Alone, Forget, Family and Friends, Trouble) and S2...