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The editorial introduction to Volume 27, Issue 2 of Current Issues in Education offers a tribute to Dr. David C. Berliner and provides an overview of the issue’s eleven articles. In Part I, “Always in Our Corner: Hon...

Introduction Early open fracture management aims to minimise the risk of complications. For the most severe open fracture wounds, multiple irrigation and debridement surgeries are required to overcome severe wound contam...

James S Cho,1,2 Julia Zhu,2 Pritesh Topiwala,1,2 David Hao1,2 1Department of Anesthesiology, Mass General Brigham, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USACorrespondence: David Hao, Department of Anesthe...

Acute myeloid leukemia (AML) is the most frequent type of leukaemia in adults, often with poor outcomes due to the complex genetic landscape and low treatment efficacy. Autophagy, a conserved degradation process, plays a...

Abstract Background Viral and infectious illnesses can exert profound and enduring effects on population health and well-being. In the aftermath of SARS-CoV-2 infection, post-acute sequelae, collectively referred to as L...

IntroductionThe immune system is recognized as participating in the pathophysiology of psychiatric disease and there is renewed interest in identifying biomarkers of this immune activation. MethodsWe measured serum and c...

Introduction and ObjectivesAccurate diagnosis of IgE-mediated diseases requires identifying relevant allergens to guide appropriate clinical management and reduce healthcare costs (1). The ImmunoCAP Phadiatop (Thermo Fis...

This paper introduces RecoveryWorks, a multi-system recovery and vocational support program designed to expand the therapeutic landscape of recovery by increasing access to career development resources that support meani...

Abstract Glucocorticoid-producing cells of the adrenal cortex (i.e. zona fasciculata, zF) constitute the critical effectors of the hypothalamic-pituitary-adrenal axis, mediating the mammalian stress response. With glucoc...

Abstract Medicine is evolving beyond therapy largely predicated on anatomical information and towards incorporating patient-specific molecular biomarkers of disease for more accurate diagnosis and effective treatment. Th...