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Survival and predictors of mortality among adults with type 2 diabetes at a teaching hospital in Ghana: a retrospective cohort study
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Survival and predictors of mortality among adults with type 2 diabetes at a teaching hospital in Ghana: a retrospective cohort study
Issah Haruna et al · BMC · 2026 · ISSN 1471-2458
Abstract Background Mortality rates remain high among individuals with type 2 diabetes. The rising cases of Diabetes Mellitus (DM) have negatively impacted society’s development, health and have impoverished individual...
LCC LCC:Public aspects of medicineIdioma eng
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A nomogram for predicting the disease-free survival of patients with pancreatic ductal adenocarcinoma
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A nomogram for predicting the disease-free survival of patients with pancreatic ductal adenocarcinoma
Yao Pan et al · BMC · 2026 · ISSN 1471-2342
Abstract Background Accurate prediction of disease-free survival after radical resection in patients with pancreatic ductal adenocarcinoma (PDAC) remains challenging. Therefore, this study establishes and validates a pre...
LCC TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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A risk scoring model for lung squamous cell carcinoma based on epithelial-mesenchymal transition-related genes: an integrative analysis of prognosis and immune infiltration characteristics
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A risk scoring model for lung squamous cell carcinoma based on epithelial-mesenchymal transition-related genes: an integrative analysis of prognosis and immune infiltration characteristics
Anqi Zhang et al · PeerJ Inc · 2026 · ISSN 2167-8359
Background Despite expanding therapeutic options, the prognosis of lung squamous cell carcinoma (LUSC) remains poor. Immune checkpoint inhibitors benefit only a subset of patients, and epithelial–mesenchymal transition...
LCC LCC:Medicine; LCC:Biology (General)Idioma eng
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ATP2C2–PLA2R1 axis underlies lipid metabolism modulation and invasion in papillary thyroid carcinoma mediated by a VGIC signature
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ATP2C2–PLA2R1 axis underlies lipid metabolism modulation and invasion in papillary thyroid carcinoma mediated by a VGIC signature
Linlin Sun et al · Springer · 2026 · ISSN 2730-6011
Abstract Objective Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with rising incidence globally. Current prognostic markers often lack precision for individualized management. This study develo...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Adjuvant short-course radiotherapy combined with chemotherapy and a PD-1 inhibitor for resected mucosal melanoma: study protocol for a single-arm, prospective, phase II trial
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Adjuvant short-course radiotherapy combined with chemotherapy and a PD-1 inhibitor for resected mucosal melanoma: study protocol for a single-arm, prospective, phase II trial
Yan Wang et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Mucosal melanoma (MM) carries a high risk of postoperative relapse and poorer survival than cutaneous disease. Prospective data from China support adjuvant temozolomide–cisplatin (TMZ/DDP) in resected MM, ...
LCC LCC:MedicineIdioma eng
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Association between B and T lymphocyte attenuator/herpes virus entry mediator immunoregulatory axis and outcome prediction in a mixed critically ill population
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Association between B and T lymphocyte attenuator/herpes virus entry mediator immunoregulatory axis and outcome prediction in a mixed critically ill population
Stelios Kokkoris et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract B and T lymphocyte attenuator (BTLA) and herpes virus entry mediator (HVEM) are emerging immune checkpoint molecules implicated in immune dysregulation during critical illness. We investigated the prognostic rel...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Association between ROX index and in-hospital mortality in critically ill patients with chronic obstructive pulmonary disease: A retrospective cohort study based on two large databases
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Association between ROX index and in-hospital mortality in critically ill patients with chronic obstructive pulmonary disease: A retrospective cohort study based on two large databases
Guangdong Wang MD et al · SAGE Publishing · 2026 · ISSN 2047-7163
Objective The ROX index, combining oxygenation and respiratory rate, is widely used to assess respiratory failure. However, its prognostic value in critically ill patients with chronic obstructive pulmonary disease (COPD...
LCC TENDOlNjaWVuY2U~; TENDOlRlY2hub2xvZ3k~Idioma eng
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Association between cardiopulmonary bypass weaning time and adverse outcomes in patients with aortic dissection who underwent total arch replacement combined with stented elephant trunk implantation
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Association between cardiopulmonary bypass weaning time and adverse outcomes in patients with aortic dissection who underwent total arch replacement combined with stented elephant trunk implantation
Peiquan Li et al · BMC · 2026 · ISSN 1471-2261
Abstract Background Postoperative complications in patients with acute type A aortic dissection (ATAAD) significantly affect their prognosis. This study investigates the association between cardiopulmonary bypass(CPB) we...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Association between female sex and short-term mortality after coronary artery bypass grafting: a retrospective cohort study
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Association between female sex and short-term mortality after coronary artery bypass grafting: a retrospective cohort study
Jiasen Ma et al · BMC · 2026 · ISSN 1749-8090
Abstract Background With the changes in coronary artery bypass grafting (CABG) guidelines, the demographic composition of surgical patients and their preoperative baseline characteristics have also shifted. However, it r...
LCC TENDOlN1cmdlcnk~; LCC:AnesthesiologyIdioma eng
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Association of abnormal echocardiographic diastolic parameters and postoperative major adverse cardiac events and mortality in patients undergoing hip fracture surgery: a retrospective cohort study
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Association of abnormal echocardiographic diastolic parameters and postoperative major adverse cardiac events and mortality in patients undergoing hip fracture surgery: a retrospective cohort study
Rahul Mehta et al · BMC · 2026 · ISSN 2047-0525
Abstract Background Perioperative diastolic dysfunction has been proposed as an independent predictor of postoperative major adverse cardiac events (MACE) after noncardiac surgery. However, prior studies have largely foc...
LCC TENDOlN1cmdlcnk~Idioma eng
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Association of systemic immune-inflammation index with all-cause mortality in lung cancer patients undergoing radiotherapy: a retrospective cohort study
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Association of systemic immune-inflammation index with all-cause mortality in lung cancer patients undergoing radiotherapy: a retrospective cohort study
Jianwei Yang et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundThe systemic immune-inflammation index (SII) has emerged as a widely studied inflammatory biomarker reflecting the balance between host inflammatory and immune status, although evidence in lung cancer patients ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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BTG3 suppresses oral squamous cell carcinoma progression by inhibiting PI3K/AKT signaling and EMT
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BTG3 suppresses oral squamous cell carcinoma progression by inhibiting PI3K/AKT signaling and EMT
Su Zhang et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract B-cell translocation gene 3 (BTG3), a tumor suppressor, is reduced in expression in several malignancies, including ovarian cancer, colorectal cancer, and gastric cancer, but its role in oral squamous cell carci...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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CALLY index provides improved prognostic stratification compared with other inflammation-based scores in glioblastoma treated with the stupp protocol
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CALLY index provides improved prognostic stratification compared with other inflammation-based scores in glioblastoma treated with the stupp protocol
Beril Balci Topuz et al · BMC · 2026 · ISSN 1471-2407
Abstract Background Systemic inflammation and nutritional status are increasingly recognized as prognostic determinants in glioblastoma (GBM). The CRP–albumin–lymphocyte (CALLY) index integrates inflammatory and immu...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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CD71 as an independent prognostic factor in pediatric B-ALL: a regional multicenter retrospective study in Southern China (SCCLG-ALL-2016)
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CD71 as an independent prognostic factor in pediatric B-ALL: a regional multicenter retrospective study in Southern China (SCCLG-ALL-2016)
Xing-Fei Chen et al · SAGE Publishing · 2026 · ISSN 1758-8359
Background: Despite high cure rates in pediatric B-cell acute lymphoblastic leukemia (B-ALL), relapse remains a major challenge. Current risk stratification systems fail to identify a subset of occult high-risk (HR) pati...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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CXCL12/ZNF503/GATA3/MMP1 axis promotes tumor progression and metastasis of triple-negative breast cancer
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CXCL12/ZNF503/GATA3/MMP1 axis promotes tumor progression and metastasis of triple-negative breast cancer
Siyu Liu et al · BMC · 2026 · ISSN 1465-542X
Abstract Background Triple-negative breast cancer (TNBC) is a subtype of breast cancer which has the poorest prognosis, with high recurrence and metastasis rates. ZNF503 (Zinc finger elbow-related proline domain protein ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Clinical impact of novel cardiovascular and immune system dosimetric parameters in stage III NSCLC patients treated with radiotherapy
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Clinical impact of novel cardiovascular and immune system dosimetric parameters in stage III NSCLC patients treated with radiotherapy
Francesco Dionisi et al · BMC · 2026 · ISSN 1748-717X
Abstract Purpose To evaluate the clinical impact of the dose to structures not routinely constrained in the radiation treatment (RT) of stage III NSCLC, such as the left anterior descending artery (LAD) and the estimated...
LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neSIdioma eng
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Clinical presentation and treatment outcomes in a South African thrombotic thrombocytopenic purpura cohort with and without HIV
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Clinical presentation and treatment outcomes in a South African thrombotic thrombocytopenic purpura cohort with and without HIV
Nokubonga Vundla et al · AOSIS · 2026 · ISSN 1608-9693
Background: HIV is the most common cause of secondary thrombotic thrombocytopenic purpura (TTP) in South Africa.  Objectives: To assess the clinical presentations and outcomes of patients treated for HIV-associated and...
LCC LCC:Public aspects of medicine; TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis
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Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis
Qingcheng Zhu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
BackgroundElderly patients with severe acute pancreatitis (SAP) have high mortality, yet reliable early risk stratification tools remain limited. The lactate-to-albumin ratio (LAR) has emerged as a potential prognostic b...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Clinicopathological and prognostic significance of stromal maturity, tumour-infiltrating lymphocytes, and systemic environment in breast cancer
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Clinicopathological and prognostic significance of stromal maturity, tumour-infiltrating lymphocytes, and systemic environment in breast cancer
Qing Guo et al · BMC · 2026 · ISSN 1746-1596
Abstract Background The tumour microenvironment and systemic inflammatory environment are related to the diagnosis, treatment and prognosis of various tumours. This study aimed to evaluate the clinicopathological signifi...
LCC TENDOlBhdGhvbG9neQ~~Idioma eng
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Comprehensive clinicopathological and prognostic analysis of primary pulmonary lymphoepithelial carcinoma: a retrospective cohort study
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Comprehensive clinicopathological and prognostic analysis of primary pulmonary lymphoepithelial carcinoma: a retrospective cohort study
Meihong Yao et al · BMC · 2026 · ISSN 1746-1596
Abstract Background Primary pulmonary lymphoepithelial carcinoma (PPLEC) is an extremely rare subtype of lung squamous cell carcinoma (LUSC). This study aims to comprehensively characterize clinicopathological and molecu...
LCC TENDOlBhdGhvbG9neQ~~Idioma eng
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Construction and evaluation of a bladder cancer prognosis model based on super-enhancer-associated genes
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Construction and evaluation of a bladder cancer prognosis model based on super-enhancer-associated genes
Lieyu Xu et al · Springer · 2026 · ISSN 2730-6011
Abstract Introduction Bladder cancer (BLCA) is a malignant tumour that occurs on the mucosa of the bladder. It accounts for the first place in the incidence of genitourinary tumours in China. BLCA is characterized by hig...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Does lateralization and distalization affect revision rates and patient experience in primary stemmed reverse total shoulder arthroplasty?
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Does lateralization and distalization affect revision rates and patient experience in primary stemmed reverse total shoulder arthroplasty?
David R.J. Gill, MB ChB, FRACS, FAOrthA et al · Elsevier · 2026 · ISSN 2666-6383
Background: This study examined the association between distalization and lateralization of implant components and revision outcomes and patient-reported outcome measures (PROMs) following primary total stemmed reverse s...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~; LCC:Diseases of the musculoskeletal systemIdioma eng
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Efficacy and safety analysis of CAR-T cell salvage therapy in relapsed/refractory diffuse large B-cell lymphoma after failure of bispecific antibody treatment
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Efficacy and safety analysis of CAR-T cell salvage therapy in relapsed/refractory diffuse large B-cell lymphoma after failure of bispecific antibody treatment
Fuli Li et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) who failed bispecific antibody (BsAb) therapy face an extremely poor prognosis, necessitating exploration of effective salva...
LCC LCC:MedicineIdioma eng
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Efficacy and safety of artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) for the treatment of uncomplicated Plasmodium falciparum malaria among children 6–59 months in three sentinel sites of Sierra Leone, 2021–2022
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Efficacy and safety of artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) for the treatment of uncomplicated Plasmodium falciparum malaria among children 6–59 months in three sentinel sites of Sierra Leone, 2021–2022
Irene Cavros et al · BMC · 2026 · ISSN 1475-2875
Abstract Antimalarial drug resistance leads to increased treatment failures, prolonged illness, and increased mortality. The World Health Organization (WHO) recommends malaria-endemic countries regularly (ideally biennia...
LCC TENDOkFyY3RpYyBtZWRpY2luZS4gVHJvcGljYWwgbWVkaWNpbmU~; TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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