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Abstract Background/Objective Asthma medication adherence, measured by the asthma medication ratio (AMR), has been shown to be a reliable predictor of exacerbations among children with asthma. We developed a Markov model...

Abstract Background Bronchial asthma is a prevalent long-term respiratory condition in children. It is characterized by chronic airway inflammation. Asthma patients have a higher risk of developing chronic kidney disease...

Abstract The introduction of biologicals interfering with the interleukin-5 (IL-5) pathway has revolutionized the treatment of severe eosinophilic asthma (SEA), rendering remission an achievable goal even in patients wit...

Objective: This study aims to analyze the comorbidity profile of patients with severe asthma undergoing benralizumab therapy in a Romanian academic center, focusing on the impact of these comorbidities on disease managem...

Background: Adolescents with asthma represent a high-risk group for poor disease control, largely due to suboptimal adherence to inhaled therapy. Despite advances in guideline-directed management, medication non-adherenc...

Background: Asthma is considered as a major public health problem in many countries. It is one of the most common chronic disease affecting both adults and children. According to world health organization there are at ...

Abstract Background Severe asthma in horses, known as severe equine asthma (SEA), is a prevalent, performance‐limiting disease associated with increased allergen‐specific immunoglobulin E (IgE) against a range of env...

Abstract Asthma is a chronic inflammatory airway disease with a rising global prevalence and impact on quality of life. Conventional therapeutics such as corticosteroids and β2-agonists are associated with various long-...

Abstract Background Prolonged exposure to environmental antigens or allergens elicits an immune response in both healthy horses and those with mild asthma. Corticosteroids often are used to treat lower airway inflammatio...

BackgroundYupingfeng Powder (YPF), a classical Chinese herbal formula composed of Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata, has demonstrated potential efficacy in the treatment of ...

Abstract In bronchial asthma, M2 macrophage polarization and PI3K/Akt/mTOR pathway activation are critically implicated in airway inflammation and remodeling. This study employed an OVA-induced asthmatic mouse model to e...

Abstract A prompt and precise diagnosis is necessary to lessen the worldwide burden of asthma, a common chronic respiratory condition. Spirometry is one of the resource-intensive conventional methods that frequently misc...

Asthma is linked to increase the risk of chronic obstructive pulmonary disease (COPD), but the causal relationship remains uncertain due to confounding factors. Eosinophilic and neutrophilic inflammation are known pathwa...

ABSTRACT Background and Aims Evidence supporting the association between anaemia and lower iron intakes during pregnancy with an increased risk of childhood asthma remains unclear. This study aimed to investigate whether...

Abstract This single-center randomized controlled trial evaluated whether Chaipu Decoction used as an adjunct to Seretide improves clinical and immunological outcomes in patients with bronchial asthma. A total of 300 adu...

Abstract Background Mild asthma in horses decreases racing performance and impairs gas exchange. The efficacy of treatment on performance is unknown. Hypothesis Treatment targeting lung inflammation improves V˙O2peak in...

Abstract Effective respiratory therapy relies heavily on inhaler device efficiency and patient technique. While device performance is well-documented in idealized induction ports, there remains a critical lack of data in...

Abstract Background Equine asthma (EA) causes airflow impairment, which increases in severity with exercise. Electrical impedance tomography (EIT) is an imaging technique that can detect airflow changes in standing healt...

Abstract Background Asthma in horses is associated with nonspecific respiratory clinical signs and may be manifested only as exercise intolerance. Its diagnosis relies on bronchoalveolar lavage fluid (BALF) cytology in t...

Abstract Background A study reported low systemic availability of injectable dexamethasone nebulized to healthy horses using the Flexineb mask. When used in horses with severe asthma and a different nebulizer, lack of ef...

BackgroundAsthma is traditionally conceptualized as a T helper 2 (Th2)-mediated inflammatory airway disease. However, increasing evidence suggests that primary immune dysregulation may underlie or phenotypically mimic as...

Abstract Background The diagnostic value of allergen‐specific immunoglobulin E (IgE) in horses with asthma is uncertain. A recently developed protein microarray detected abnormally high latex‐specific IgE concentrati...

Abstract Background There are limited data on potential dysbiosis of the airway microbiota in horses with asthma. Hypothesis/Objectives We hypothesized that the respiratory microbiota of horses with moderate asthma is al...

Abstract Background Mild‐moderate asthma is common in horses. Inhaled ciclesonide has been approved only for treatment of severe asthma in horses. Hypothesis/Objectives We hypothesized that a 10‐day treatment course ...