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Mild cognitive impairment (MCI) and dementias, such as Alzheimer’s disease (AD)-induced dementia and vascular dementia, are major public health burdens. The blood-brain barrier (BBB) disruption, systemic inflammation, ...

Background and purposeThe aging brain is particularly sensitive to alterations in selenium status. Selenium deficiency has been associated with impaired neural function, cognitive decline, and increased vulnerability to ...

Abstract Objective Based on the bidirectional communication mechanism of the gut-brain axis, this study aims to systematically elucidate the interactive pathways between gut microbiota and insomnia, review the research p...

A growing number of studies are now utilizing human organotypic brain slice cultures (OBSC), enabled by improved long-term culture protocols that support the investigation of human-specific cellular physiology. Human OBS...

As Nigeria continue to grapple with development challenges due to shortfalls of professional in the various sectors, all efforts aimed at curtailing the increasing spread of migration from Nigeria have not yielded the de...

This study presents a novel machine learning approach to assess human well-being through the analysis of brain wave activities. We developed a Random Forest classifier to categorize brain wave patterns into three states ...

Extensive research has demonstrated that music enhances cognitive functions, such as learning, reasoning, and memory. This study investigated the influence of music on short- and long-term memory while learning through t...

BackgroundHigh blood pressure (BP) is a known risk factor for dementia, but the relationships between BP and gross brain volumes are mixed and are understudied in groups who are at particularly high risk for dementia, su...

Abstract Invasive intracranial pressure (ICP) monitoring is considered the gold standard for the management of patients with an acute brain injury and at risk of developing intracranial hypertension (IH). However, invasi...

Optical brain-computer interface (OBCI) represents an emerging class of neural interaction technologies that use “light” as an information carrier to enable the acquisition, decoding, and modulation of neural signals...

Developing effective drugs for Alzheimer’s Disease (AD) is critically limited by insufficient brain exposure. To address this, structural optimization was employed to balance physicochemical properties and enhance bloo...

Abstract Fetal growth restriction (FGR) occurswhen the fetus does not reach its intrauterine potential for growth and development as a result of compromise in placental function. It is a condition that affects 5 to 10% o...

Background: A brain tumor is a tumor that is most known for its dangerous progressivity. Brain tumor is classified into primary and metastatic types. One of the management for primary brain tumors is radiotherapy. This s...

Abstract The global rise in mental health conditions has prompted interest in interventions that act beyond conventional psychopharmacology. Psychobiotics, broadly understood as live microorganisms or microbe‐derived p...

Neurological disorders such as post-stroke hemiplegia, spinal cord injury, and Parkinson disease represent a major global health burden. Brain-computer interface (BCI), which creates direct communication pathways between...

Abstract Background Stereotactic brain biopsy (SBB) allows for histopathologic diagnosis of brain tumors. Adverse events (AE) occur in 5 to 29% of dogs after SBB, but risk factors associated with developing AE are poorly...

Objective: Brain metastases (BMs) are the most common intracranial tumors in adults and represent a major cause of morbidity and mortality in patients with systemic malignancies. This study aimed to evaluate the clinical...

In this study, Tc-99m Hexamethylpropyleneamine oxime (HMPAO) brain perfusion single photon emission computed tomography (SPECT) was performed in patients with aluminum intoxication (AI) and expectable aluminum neurotoxic...

The need for early and precise identification of abnormalities has made the detection and classification of brain tumours essential components of medical diagnosis. Because brain tumours are naturally complex and can hav...

Brain-computer interface (BCI) is a neuro-engineering technology that establishes a direct communication pathway between the brain and external devices. It can realize bidirectional information interaction between the br...

IntroductionHuman space exploration is progressing into an unprecedented era characterized by extended-duration missions, the establishment of permanent lunar bases, and planned crewed voyages to Mars. These activities i...

Objective: This paper tackles the cross-sessions variability of electroencephalography-based brain-computer interfaces (BCIs) in order to avoid the lengthy recalibration step of the decoding method before every use. Meth...

BackgroundFrailty is significantly more prevalent in individuals with Parkinson’s disease (PD) than in general population, yet the underlying neuropathophysiological mechanisms remain poorly understood. This study aime...

Objective This study aimed to explore the influence of the angiotensin-(1–7)/Mas receptor and angiotensin II/angiotensin II type 1 receptor pathways on pyroptosis during sepsis and their subsequent effects on cognitive...