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Abstract Ecological momentary assessment (EMA) is a tool facilitating the repeated collection of real-time data in naturalistic settings that can be applied to clinical research. Despite established methodological streng...

ObjectiveThis study aims to investigate the correlation between trace element concentrations, 25-hydroxyvitamin D [25(OH)D] levels, and the severity of tic disorders (TD) in children from the Hubei region. Additionally, ...

Yueling Wang,1,* Juntao Yang,2,* Ying Ye,1 Lihua Lu,1 Haolei Wang,1 Peipei Guo,1 Na Hou,1 Xiaohan Huang,3 Cairui Li4 1Department of Medical Imaging, Mental Hospital of Yunnan Province, Kunming, 650000, Pe...

Abstract Background Blood-based biomarkers could improve the precision of Alzheimer’s disease (AD) clinical diagnosis and expand access to targeted treatments. Therefore, we evaluated the diagnostic accuracy of plasma ...

Abstract Background As dementia cases continue to rise, effective prevention strategies are urgently needed. However, objective biomarkers that directly reflect lifestyle factors remain limited. Life’s Essential 8 (LE8...

Abstract Background Decompressive craniectomy (DC) is a life-saving measure in severe traumatic brain injury (TBI), but its long-term functional outcome and the time of subsequent cranioplasty remain debated. Recent evid...

BackgroundParkinson’s disease (PD) is a progressive neurodegenerative disorder whose advanced stages (Hoehn & Yahr IV–V) place significant demands on informal caregivers, leading to multidimensional burden. Altho...

Abstract The proposed empirical research investigated the impact of emotional maturity on job satisfaction among healthcare employees. The study further examined the mediating and moderating roles of emotional intelligen...

Abstract Background Impaired upper extremity (UE) function is a major contributor to disability after stroke. Combining robotic devices with functional electrical stimulation (FES) has emerged as a promising hybrid appro...

Abstract Background Gait impairments following chronic neurological conditions, such as spinal cord injury (SCI), represent a major challenge for rehabilitation, with limited options to sustain functional recovery and pa...

Abstract Background Children with Unilateral Cerebral Palsy (UCP) are characterized by significant upper limbs (ULs) impairment that hinders daily activities and participation, requiring accurate assessment. Although mot...

Abstract Background Traumatic brain injury (TBI) needs inter-disciplinary care through pre-hospital resuscitation, emergency and neurosurgical care, neurocritical care, and structured neurorehabilitation to maximize surv...

Abstract Fecal microbiota transplantation (FMT) has emerged as a novel approach for understanding anorexia nervosa (AN), a complex eating disorder characterized by severe underweight, fear of weight gain and distorted bo...

Abstract Background Holmes tremor (HT) is a rare, symptomatic movement disorder characterized by a low-frequency tremor present at rest, with postural and intentional components. It is typically caused by combined lesion...

IntroductionParkinson’s disease (PD) is the second most common neurodegenerative disorder. The risk of frailty is significantly higher in patients with PD than in age-matched individuals without PD. This study aimed to...

Introduction: Olfactory Reference Syndrome (ORS) is a rare, under-recognized, and understudied psychiatric condition characterized by a persistent belief about the perceived odor, ideas of reference, and engagement in re...

Abstract Background Scurvy has re-emerged in association with neurodevelopmental and eating disorders, particularly selective eating. This study aimed to investigate the clinical characteristics of pediatric scurvy cases...

Abstract Background Primary intramuscular hydatid disease is an exceptionally rare form of Echinococcus granulosus infection, accounting for only 0.5–5% of cases. Paravertebral muscle involvement is particularly uncomm...

Abstract INSPIRE-PNRM+ (short for InterdiSciPlinary and InteRsectoral telemedIcal Evaluation, Coordination and Therapy at the ParkinsonNet RheinMain+) is an one-year, multicentre, interventional, open-label, two-arm, 1:1...

Abstract Background Takotsubo syndrome (broken-heart syndrome) is considered a cardiac disorder typically associated with exposure to severe psychological or physical stress, and it clinically resembles acute coronary sy...

Abstract Background Anti-amyloid monoclonal antibodies are entering clinical practice for early symptomatic Alzheimer’s disease (AD), but European real-world data on feasibility, safety, and biomarker monitoring remain...

Introduction Reproductive health impacts mental health. Consequently, reproductive factors should be assessed in psychotherapy to ensure correct differential diagnosis, precise case conceptualisation and efficient treatm...

IntroductionMusic-induced analgesia (MIA) has significant clinical value for patients with fibromyalgia (FM) and serves as a key model for understanding the complex neural mechanisms underlying the effects of music on ph...

Introduction: Social Anxiety Disorder (SAD) is one of the most common forms of anxiety. SAD typically begins in late adolescence and is the cause of low self-esteem. This study aimed to investigate the unidentified cause...