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Introduction Interaction plays a central role in the delivery of care and in supporting participation and well-being in healthcare. For people living with advanced dementia, cognitive and communicative impairments can re...

Introduction Oesophageal cancer has a poor prognosis and oesophagectomy has increasingly adopted minimally invasive techniques, but delayed gastric conduit emptying (DGCE) still occurs in ~10–50% of patients, depending...

Introduction Despite advances in acute treatment, stroke remains the first cause of acquired disability. Today, there is no effective pharmacological therapy to improve recovery beyond the acute phase. Preclinical studie...

Introduction Sarcoidosis is a heterogeneous granulomatous disease with highly variable clinical trajectories, yet no validated biomarkers exist to distinguish progressive sarcoidosis (P-sarcoidosis) from non-progressive ...

Background HIV is a major health challenge in Kenya, where prevalence exceeds global averages. Achieving viral suppression depends on consistent adherence to antiretroviral therapy (ART), but individuals in neighbourhood...

Introduction Overweight and obesity are major global public health challenges and increase the risk of type 2 diabetes, dyslipidaemia, hypertension and cardiovascular disease. Exercise is a safe and cost-effective non-ph...

Introduction Arginine vasopressin (AVP) and oxytocin (OXT) are both hormones released from the posterior pituitary. While AVP primarily regulates water reabsorption in the kidneys, OXT plays a key role in socioemotional ...

Introduction There are national calls for reducing physician administrative burden. While interest in digital scribes (DS) is growing, there is limited evidence evaluating their safety and effectiveness. In contrast, hum...

Introduction Non-suicidal self-injury (NSSI) is defined as the deliberate harm to one’s body without suicidal intent. Although individuals engaging in NSSI do not intend to die, repetitive self-injury may increase the ...

Introduction Early open fracture management aims to minimise the risk of complications. For the most severe open fracture wounds, multiple irrigation and debridement surgeries are required to overcome severe wound contam...

Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of morbidity and mortality due to chronic liver disease. There is an extensive body of evidence focusing on pharmacotherapy...

Introduction Behavioural and psychological symptoms of dementia (BPSD) affect up to 80% of people with dementia and pose significant challenges in the context of care. Psychosocial interventions have been recommended as ...

Introduction Access to safe, high quality, acceptable and sustainable general practice (GP) and primary care services is essential to improved health outcomes and quality of life for people living in residential aged car...

Introduction Lung cancer (LC) is the leading cause of cancer-related mortality worldwide, primarily due to diagnosis at advanced stages. Although low-dose computed tomography (LDCT) screening reduces lung cancer mortalit...

Abstract Background Policy makers need access to reliable data to monitor and evaluate the progress of development outcomes and targets such as sustainable development outcomes (SDGs). However, significant data and evide...