NODOVOX | Discovery

Hepatocyte SLCO4C1 is a cAMP uptake transporter for inhibiting lipogenesis and a therapeutic target for MASLD

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Hepatocyte SLCO4C1 is a cAMP uptake transporter for inhibiting lipogenesis and a therapeutic target for MASLD

Xiaojia Huang et al · Nature Portfolio · 2026 · ISSN 2041-1723

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD), the most prevalent cause of chronic liver disease worldwide, currently lacks precision medicine treatments. SLCO4C1 acts as a transporter for end...

LCC TENDOlNjaWVuY2U~Idioma eng

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ID93 + GLA-3M-052-LS vaccine candidate administered by heterologous routes improves BCG efficacy against TB

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ID93 + GLA-3M-052-LS vaccine candidate administered by heterologous routes improves BCG efficacy against TB

Emily Voigt et al · Frontiers Media S.A · 2026 · ISSN 1664-3224

BackgroundNew vaccine approaches are needed against tuberculosis (TB). We sought to optimize mucosal immunogenicity and protective efficacy by modulating the adjuvant component and route of immunization of a next-generat...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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Identification and Characterization of Glanzmann Thrombasthenia in 2 Closely Related Mixed‐breed Dogs

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Identification and Characterization of Glanzmann Thrombasthenia in 2 Closely Related Mixed‐breed Dogs

L.Z. Haysom et al · Oxford University Press · 2016 · ISSN 0891-6640

Materias / palabras clave: Glanzmann thrombasthenia; Glycoprotein IIb–IIIa; Platelets

LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng

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Identification of gene targets regulated by the IclR-like regulator SL1344_3500 in Salmonella Typhimurium

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Identification of gene targets regulated by the IclR-like regulator SL1344_3500 in Salmonella Typhimurium

Thea B. Andersen et al · American Society for Microbiology · 2025 · ISSN 0021-9193

ABSTRACT Transcriptional regulation of metabolic operons is important for optimal carbohydrate use and for mitigating the accumulation of toxic intermediates. Here, we characterize SL1344_3500, encoding a putative IclR-l...

LCC LCC:MedicineIdioma eng

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Knowledge, practices, and determinants of malaria prevention in pregnancy: a cross-sectional study in Weija-Gbawe, Ghana

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Knowledge, practices, and determinants of malaria prevention in pregnancy: a cross-sectional study in Weija-Gbawe, Ghana

Jeremiah Danso Ampofo et al · Springer · 2026 · ISSN 3005-0774

Abstract Malaria in pregnancy remains a significant public health challenge in sub-Saharan Africa, with adverse health outcomes for mothers and foetuses. This study assessed knowledge, attitudes, practices and factors as...

LCC LCC:Public aspects of medicineIdioma eng

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Large-scale modeling for housing condition prediction using machine learning algorithms

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Large-scale modeling for housing condition prediction using machine learning algorithms

Kyusik Kim et al · Nature Portfolio · 2026 · ISSN 2052-4463

Abstract While housing price prediction is well-studied, the prediction of large-scale housing conditions remains underexplored due to data limitations. This paper addresses this gap by developing a machine-learning mode...

LCC TENDOlNjaWVuY2U~Idioma eng

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Levers and leverage points for pathways to sustainability

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Levers and leverage points for pathways to sustainability

Chan, Kai M. A. et al · Blackwell Publishing Ltd · 2020 · ISSN 2575-8314

Humanity is on a deeply unsustainable trajectory. We are exceeding planetary boundaries and unlikely to meet many international sustainable development goals and global environmental targets. Until recently, there was no...

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Listening for Alzheimer’s clues: machine learning analysis of multidomain speech features for cognitive impairment screening

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Listening for Alzheimer’s clues: machine learning analysis of multidomain speech features for cognitive impairment screening

Josep Blazquez-Folch et al · Frontiers Media S.A · 2026 · ISSN 1663-4365

IntroductionEarly detection of Alzheimer’s disease (AD) is critical for timely intervention, particularly during the mild cognitive impairment (MCI) stage. This study aimed to develop and evaluate a multidomain speech ...

LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng

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Measuring navigational and digital health literacy in individuals with long-term conditions: latent trait analyses using Rasch modelling

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Measuring navigational and digital health literacy in individuals with long-term conditions: latent trait analyses using Rasch modelling

Mette Haaland et al · Frontiers Media S.A · 2026 · ISSN 2296-2565

BackgroundMapping health literacy (HL) enables health information and treatment to align with individuals’ preferences and potentially makes healthcare truly person-centered. Without valid and reliable measurement tool...

LCC LCC:Public aspects of medicineIdioma eng

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Mindful self-compassion to reduce stigma among individuals diagnosed with lung cancer (MSC-LC): a pilot study protocol for a parallel-group, randomized controlled trial

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Mindful self-compassion to reduce stigma among individuals diagnosed with lung cancer (MSC-LC): a pilot study protocol for a parallel-group, randomized controlled trial

Timothy J. Williamson et al · BMC · 2026 · ISSN 2055-5784

Abstract Background Lung cancer stigma (i.e., perceived and internalized negative appraisal and devaluation associated with lung cancer) is a clinically significant psychosocial concern among individuals diagnosed with l...

LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng

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Next-Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience

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Next-Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience

Daniel J. Parker et al · Adis, Springer Healthcare · 2026 · ISSN 2193-8237

Abstract Introduction Evoked compound action potentials (ECAPs) are neurophysiological biomarkers of neural activation during spinal cord stimulation (SCS). Clear distinction between ECAPs and nonphysiological signals is...

LCC LCC:AnesthesiologyIdioma eng

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Novel heterometallic uranyl-transition metal materials: Structure, topology, and solid state photoluminescence properties

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Novel heterometallic uranyl-transition metal materials: Structure, topology, and solid state photoluminescence properties

Gomez, Germán Ernesto et al · American Chemical Society · 2019 · ISSN 7243-7254

Six new uranyl hybrid materials have been synthesized solvothermally utilizing the ligands 2,2′-bipyridine-3,3′-dicarboxylic acid (H2L) and 2,2′:6′,2′′-terpyridine (TPY). The six compounds are classified as e...

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Optimal rate control in dogs with atrial fibrillation—ORCA study—Multicenter prospective observational study: Prognostic impact and predictors of rate control

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Optimal rate control in dogs with atrial fibrillation—ORCA study—Multicenter prospective observational study: Prognostic impact and predictors of rate control

Brigite Pedro et al · Oxford University Press · 2023 · ISSN 0891-6640

Abstract Background The optimal heart rate (HR) in dogs with atrial fibrillation (AF) is unknown. Impact of HR on survival needs elucidation. Hypothesis/Objectives Dogs with a 24 hours Holter‐derived meanHR ≤125 be...

LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng

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PROTOCOL: Psychometric properties of instruments for measuring elder abuse and neglect in community and institutional settings: A systematic review

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PROTOCOL: Psychometric properties of instruments for measuring elder abuse and neglect in community and institutional settings: A systematic review

Fadzilah Hanum Mohd Mydin et al · SAGE Publishing · 2023 · ISSN 1891-1803

Abstract Background The psychometric properties of elder abuse measurement instruments have not been well‐studied. Poor psychometric properties of elder abuse measurement instruments may contribute to the inconsistency...

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Past, present, and future of arenavirus taxonomy

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Past, present, and future of arenavirus taxonomy

Radoshitzky, Sheli R. et al · Springer Wien · 2015 · ISSN 1851-1874

Until recently, members of the monogeneric family Arenaviridae (arenaviruses) have been known to infect only muroid rodents and, in one case, possibly phyllostomid bats. The paradigm of arenaviruses exclusively infecting...

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Priority setting for health equality – searching for an ethical framework

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Priority setting for health equality – searching for an ethical framework

Sabrina Germain et al · Cambridge University Press · 2026 · ISSN 1744-1331

Compounded by 14 years of public welfare austerity, health equality presents a challenge that extends beyond healthcare in isolation because it also engages the more recondite politics of public health. Recent policy has...

LCC LCC:Public aspects of medicineIdioma eng

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Prospective Clinical Trial of Mycophenolate Mofetil (MMF) Duration De-Escalation in Allogeneic Hematopoietic Cell Transplantation (HCT) for Inborn Errors of Immunity: Is MMF Dispensable After Reduced Intensity Conditioning, Posttransplantation Cyclophosphamide(Ptcy)-Based HCT?

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Dimana Dimitrova et al · Rockefeller University Press · 2026 · ISSN 3065-8993

Hematopoietic cell transplantation (HCT) offers curative potential for inborn errors of immunity (IEI) patients, who often enter HCT with significant comorbidities and disease sequelae, active infections, and/or limited ...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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Quantum Cascade Laser Frequency Combs

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Quantum Cascade Laser Frequency Combs

Faist Jérôme et al · Wiley · 2016 · ISSN 2192-8606

It was recently demonstrated that broadband quantum cascade lasers can operate as frequency combs. As such, they operate under direct electrical pumping at both mid-infrared and THz frequencies, making them very attracti...

LCC TENDOlBoeXNpY3M~Idioma eng

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Quaternions and dual quaternions: singularity-free multirobot formation control

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Quaternions and dual quaternions: singularity-free multirobot formation control

Mas, Ignacio et al · RI ITBA · 2019 · ISSN 0921-0296

"Cluster space control is a method of multirobot formation keeping that considers a group of robots to be a single entity, defining state variables to represent characteristics of the group, such as position, orientation...

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Randomised controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for the management of severe open tibia fracture wounds: Beads versus VAC (BvV) protocol

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Randomised controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for the management of severe open tibia fracture wounds: Beads versus VAC (BvV) protocol

David Sanders et al · BMJ Publishing Group · 2026 · ISSN 2044-6055

Introduction Early open fracture management aims to minimise the risk of complications. For the most severe open fracture wounds, multiple irrigation and debridement surgeries are required to overcome severe wound contam...

LCC LCC:MedicineIdioma eng

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Rebuilding Global Fisheries

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Rebuilding Global Fisheries

Worm, Boris et al · American Association for the Advancement of Science · 2009 · ISSN 0036-8075

After a long history of overexploitation, increasing efforts to restore marine ecosystems and rebuild fisheries are under way. Here, we analyze current trends from a fisheries and conservation perspective. In 5 of 10 wel...

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SPNS2 exports sphingosine-1-phosphate and imports glucose

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SPNS2 exports sphingosine-1-phosphate and imports glucose

Cynthia Weigel et al · Nature Portfolio · 2026 · ISSN 2041-1723

Abstract Spinster homolog 2 (SPNS2) exports the bioactive sphingolipid metabolite sphingosine-1-phosphate (S1P) out of cells to regulate processes important for health and diseases. However, the molecular mechanism under...

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Site-Specific Calibration of Low-Cost Particulate Matter (PM) 2.5 Monitors in the United States: A Comparison of Industrial and Non-Industrial Communities

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Site-Specific Calibration of Low-Cost Particulate Matter (PM) 2.5 Monitors in the United States: A Comparison of Industrial and Non-Industrial Communities

Jung Hyun Lee et al · Springer · 2026 · ISSN 1680-8584

Abstract Particulate matter (PM) poses a significant public health concern, particularly in industrialized communities. While modern sophisticated air monitors like those deployed by the United States Environmental Prote...

LCC TENDOlNjaWVuY2U~Idioma eng

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Supplementation of Vitamin K1 in Dogs With Chronic Enteropathy

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Supplementation of Vitamin K1 in Dogs With Chronic Enteropathy

Jillian Myers Smith et al · Oxford University Press · 2025 · ISSN 0891-6640

ABSTRACT Background Information regarding measurement and supplementation of vitamin K1 (vitK1) in dogs with chronic enteropathy (CE) is limited. Hypothesis/Objectives Compare vitK1 concentrations of healthy dogs to dogs...

LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng

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