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Abstract Hypoxia is a defining feature of triple-negative breast cancer (TNBC), driving invasion, metastasis, and therapy resistance. Understanding the molecular effectors of hypoxia is essential to identify new therapeu...

Resumo É feita a revisão taxonómica de Jacqueshuberia Ducke (Leguminosae-Caesalpinioideae), gênero este endémico do norte da América do Sul. No tratamento, foram reconhecidas três espécies, sendo duas brasileiras...

Aims: Acute hand and wrist infections can be devastating, with a substantial burden in low- and middle-income countries (LMICs) compared with high-income countries. Access to treatment, particularly surgery, can be limit...

The p53 transcription factor plays a key role both in cancer and in the cell-intrinsic response to infections. The ORFEOME project hypothesized that novel p53-virus interactions reside in hitherto uncharacterized, unknow...

Abstract This is a protocol for a co‐registered Cochrane and Campbell Review (Methodology). The objectives are as follows: To identify, describe and assess methods for: when to replicate a systematic review; how to rep...

Introduction There are serious and long-term effects of air pollution on children, thus the Royal College of Physicians of Edinburgh, Air Pollution Working Group has evaluated whether air quality was being sufficiently m...

Introduction Early open fracture management aims to minimise the risk of complications. For the most severe open fracture wounds, multiple irrigation and debridement surgeries are required to overcome severe wound contam...

Purpose Understanding the level of fatigue experienced by adolescents and adults with cerebral palsy (CP) in low- and middle-income countries is crucial, as it can inform healthcare workers in the assessment, prevention,...

Abstract Particulate matter (PM) poses a significant public health concern, particularly in industrialized communities. While modern sophisticated air monitors like those deployed by the United States Environmental Prote...

Abstract Background Tobacco cessation markedly improves cancer treatment outcomes. As part of the National Cancer Institute (NCI) Cancer Moonshot, the Cancer Center Cessation Initiative (C3I) funded 52 U.S. National Canc...

Abstract Background Tigilanol tiglate (TT) is a novel small molecule for intratumoral treatment of nonmetastatic mast cell tumors (MCTs) in dogs. In a randomized controlled clinical study, 75% of dogs that received a sin...

Este artículo se ocupa de la posibilidad y legitimidad de integrar las soluciones de dos problemas económicos internacionales. El primero es el de la reforma monetaria internacional y el segundo el de incrementar el fl...