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Serum estradiol (E2), prolactin (PRL), LH, FSH, B2-M, PTH, Cα phosphorus (P) levels and thyroid function tests (TT3, TT4, JT3, JT4 and TSH) were studied. The relationships between hormonal changes and bone metabolic par...

Titanium is a gold standard material in dental implant treatment due to its biocompatibility and excellent mechanical strength. However, titanium has no bioactivity and osteoconductivity. This has led to studies to devel...

Bone infection is a severe disease caused by microbial invasion of bone tissue, characterized by inflammatory responses, bone destruction, and impaired repair. Its high recurrence rate and refractory nature have posed si...

Abstract Background Matrix stiffness is a key feature of the mechanical microenvironment. Periodontal tissue is a multicomponent structure composed of cementum, periodontal ligament, and alveolar bone, and is essential f...

Abstract The aim of this study is to determine the some physicochemical (proximate composition, pH and aw values) and reconstitution (wettability, dispersibility and solubility index (SI)) properties of spray-dried bone ...

A pathological shift in bone marrow mesenchymal stem cell (BMSC) differentiation towards adipogenesis at the expense of osteogenesis is a key cellular driver of osteoporosis induced by glucocorticoids or estrogen deficie...

IntroductionBone defect repair remains a clinical challenge due to the complex inflammatory microenvironment that regulates mesenchymal stem cell fate.MethodsBased on our previous work demonstrating that quercetin-loaded...

OBJECTIVES: Recently, angiotensin II (Ang II) receptorsubtype I binding sites has been demonstrated on bone cell precursors and extensive area of research has been focused on the effects of renin angiotensin system (RAS)...

Abstract Knee osteoarthritis (KOA) is a degenerative joint condition characterized by progressive cartilage deterioration and chronic pain, leading to functional impairment. Bone marrow-derived orthobiologics, such as bo...

Subchondral bone H-type angiogenesis and increased permeability are critical in osteoarthritis (OA) progression, yet the underlying regulatory mechanisms remain unclear. This study utilized proteomic analysis to identify...

Low bone mineral density (BMD) is one of the risk factors for bone fracture. The incidence of bone fracture is highest among patients with chronic renal failure. There is little data about the BMD of patients undergoing ...

OBJECTIVE: The prevalence of atherosclerosis and osteoporosis increase with age. An association has been demonstrated between cardiovascular diseases and low bone mineral density. We aimed to investigate the association ...

ABSTRACT Although chemotherapy‐induced bone loss is well‐recognized during breast cancer treatment, the underlying mechanism remains to be further elucidated, especially in patients with obesity. In this study, the o...

Various biomaterials have been utilized as additional material to help tissue regeneration in the open flap debridement (OFD) procedure. Platelet-rich fibrin (PRF) is an autologous platelet concentrate that contains many...

OBJECTIVE: Chronic kidney disease - mineral and bone disorder (CKD -BMD) is a worldwide challenge in hemodialysis patients (HD). Widespread use and improved methods of HD may have changed the spectrum of locomotor system...

Abstract The bone is an important body organ due to its role in locomotion, protection and mineral homeostasis. Bone health is affected by various intrinsic and extrinsic factors like genetics, diet, environment and immu...

Bone fractures are mostly caused by trauma and disease. In the therapeutic process of bone healing which often meets some constraints, bone graft is mainly used to ensure that the healing process takes place. A fiber rei...

Osteoporosis constitutes a major public health problem through its association with age related fractures. Fracture rates are generally higher in caucasian women than in other populations. Important determinants include ...

We examined a new method, based on the retention of fluoride (F), for estimating bone remodelling in rats and human beings. We tested the validity of the new methodology by comparing normal Sprague Dawley rats (Controls,...

The utilization of fish processing by-products represents an important strategy to improve production efficiency and support zero-waste principles. Milkfish (Chanos chanos) bone by-products, generated from deboned milkfi...

Abstract Aims This study aimed to assess the three-dimensional effects of orthodontic premolar extraction in Class II division 1 malocclusion cases treated with fixed appliances on maxillary bony changes (alveolar bone t...

BackgroundRare epidermal growth factor receptor (EGFR) mutations have a low incidence, and their response to EGFR tyrosine kinase inhibitors (TKI) has not been sufficiently studied. L747P is a rare EGFR mutation located ...

Treatment of infrabony pocket makes use of bone graft material demineralized freeze dried bone allograft (DFDBA) from different individuals which has undergone demineralization process and it is osteoinductive. Enhanceme...

Abstract Bone defects present significant challenges in clinical practice due to the limitations of traditional treatments. Compared to traditional cell therapies, exosome-based therapies have emerged as a promising alte...