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Abstract This update to the 2019 Canadian Hereditary Angioedema (HAE) Guideline broadens its focus to include the management of patients with HAE worldwide, building on its established international framework. It has bee...

Abstract Background Volatile anesthetics are widely used for sedation in intensive care. Being potent greenhouse gases, their efficient utilization is imperative. We investigated whether the efficiency of anesthetic refl...

Bakgrunn: Tidligere intensivpasienter, og spesielt de som har vært sederte, kan ha økt risiko for å oppleve psykiske stressfaktorer som hukommelsestap og tilbakevendende minner, vrangforestillinger og/eller hallusinas...

Abstract Background Adequate housing is a basic human right. The many millions of people experiencing homelessness (PEH) have a lower life expectancy and more physical and mental health problems. Practical and effective ...

Abstract BackgroundThe Sustainable Development Goals (SDGs) aim to eradicate poverty and inequality while ensuring that all individuals enjoy good health. Among these, target 3.1 seeks to reduce the global ma...

Abstract Background Parents who experience adverse social risk factors of health (SRFOH) are at risk for child welfare involvement, and those with opioid and/or methamphetamine use (O/MU) and mental health (MH) disorders...

BACKGROUND: Hyperglycemia and insulin resistance are common in critically ill patients, even if they have not previously had diabetes. Whether the normalization of blood glucose levels with insulin therapy improves the p...

OBJECTIVE: To determine the incidence, cost, and outcome of severe sepsis in the United States. DESIGN: Observational cohort study. SETTING: All nonfederal hospitals (n = 847) in seven U.S. states. PATIENTS: All patients...

BACKGROUND: Long-term microvascular and neurologic complications cause major morbidity and mortality in patients with insulin-dependent diabetes mellitus (IDDM). We examined whether intensive treatment with the goal of m...

This paper presents the form and validation results of APACHE II, a severity of disease classification system. APACHE II uses a point score based upon initial values of 12 routine physiologic measurements, age, and previ...

The acute respiratory distress syndrome (ARDS) was defined in 1994 by the American-European Consensus Conference (AECC); since then, issues regarding the reliability and validity of this definition have emerged. Using a ...

Importance: In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of cases has increased rapidly but information on the clinical characteristics of affected patien...

BACKGROUND: Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen deliver...

Importance: There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19). Objective: To describe the clinical charac...

To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. A consensus committee of 68 international experts representing 30 international...

IMPORTANCE: Definitions of sepsis and septic shock were last revised in 2001. Considerable advances have since been made into the pathobiology (changes in organ function, morphology, cell biology, biochemistry, immunolog...

Knaus, William A. MD; Draper, Elizabeth A. RN, MS; Wagner, Douglas P. PhD; Zimmerman, Jack E. MD Author Information

The aim of the present research was to build a tool to classify patients according to drug theraphy risk so as to rationalize the use of clinical pharmaceutical resources in hospital settings. Risk factors selected in th...

Materias / palabras clave: emergency, surgery, anesthesia, intensive care medicine, epidemiological data; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid; Medicine: Surgery: Anesthesiology

Materias / palabras clave: critical care medicine, critical care, intensive care; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: anaesthesiology, intensive therapy, critical care; Medicine: Surgery: Anesthesiology; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: anesthesiology, critical care, intensive care; Medicine: Surgery: Anesthesiology; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: critical care, clinical research, intensive care, medical education; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: critical care, intensive care, emergency medicine; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid