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A classification model based on G protein-coupled estrogen receptor binding affinity: development and validation

ISSN: 10048456 · Editor / fuente: The Editorial Office of Chinese Journal of Food Hygiene

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Development and validation of a RP-HPLC method for determination of citicoline monosodium in human plasma
Artículo
Material complementario disponible Artículo SEDICI UNLP
Development and validation of a RP-HPLC method for determination of citicoline monosodium in human plasma
Bindaiya, Shailendra K. et al · SEDICI UNLP · 2011
A sensitive and specific high performance reversed phase liquid chromatographic method was developed for quantification of citicoline monosodium (CTM) in human plasma. The active drug was isocratically eluted at a flow r...
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Development and validation of an UV-spectrophotometric method for the dissolution studies of sitagliptin tablets
Artículo
Material complementario disponible Artículo SEDICI UNLP
Development and validation of an UV-spectrophotometric method for the dissolution studies of sitagliptin tablets
Ravanello, Aline et al · SEDICI UNLP · 2010
A simple UV-spectrophotometric method was developed and validated for the analysis and dissolution studies of sitagliptin phosphate in tablets. Specificity test indicated an adequate UV detection at 267 nm. The method wa...
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Method development and validation for the determination of cabergoline in tablets by capillary zone electrophoresis
Artículo
Material complementario disponible Artículo SEDICI UNLP
Method development and validation for the determination of cabergoline in tablets by capillary zone electrophoresis
Dogan, Aysegul et al · SEDICI UNLP · 2011
A capillary zone electrophoresis (CZE) method has been developed for the analysis of cabergoline in its pharmaceutical preparations. Optimized analysis conditions for cabergoline analysis were performed using 110 mM pH 5...
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Pharmaceutical topical gel: development and validation of a UV spectrophotometric method for determination of polyphenols
Artículo
Acceso abierto Artículo SEDICI UNLP
Pharmaceutical topical gel: development and validation of a UV spectrophotometric method for determination of polyphenols
Silva-Corazza, Patrícia E.R. et al · SEDICI UNLP · 2010
The objective was to develop and validate a method for the determination of total polyphenols in a vaginal gel containing a dried extract of Aroeira (Schinus terebinthifolius Raddi). The method was developed by UV spectr...
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Component-based modeling and validation of a heat pump building system using experimental data
Tesis
Acceso abierto Tesis RI ITBA
Component-based modeling and validation of a heat pump building system using experimental data
Muskalla, Lisa · Instituto Tecnológico de Buenos Aires (ITBA) · 2026
This thesis presents the development and simulation of a modular physically based thermal model of a building and a reversible R290 (propane) air-to-water heat pump, implemented in MATLAB/Simulink and Simscape. The work ...
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Single-crystal structure validation with the program<i>PLATON</i>
Artículo
Material complementario disponible Artículo OpenAlex
Single-crystal structure validation with the program<i>PLATON</i>
Anthony L. Spek · Journal of Applied Crystallography · 2003
The results of a single-crystal structure determination when in CIF format can now be validated routinely by automatic procedures. In this way, many errors in published papers can be avoided. The validation software gene...
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Structure validation in chemical crystallography
Artículo
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Structure validation in chemical crystallography
Anthony L. Spek · Acta Crystallographica Section D Biological Crystallography · 2009
Automated structure validation was introduced in chemical crystallography about 12 years ago as a tool to assist practitioners with the exponential growth in crystal structure analyses. Validation has since evolved into ...
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Automated experimentally validated antenna design framework using versatile parameterization scheme
Artículo
Material complementario disponible Artículo DOAJ
Automated experimentally validated antenna design framework using versatile parameterization scheme
Slawomir Koziel et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Modern antenna design is an intrinsic undertaking. It relies heavily on expert knowledge and computational tools, especially electromagnetic (EM) simulation software. The most daunting phase is the development o...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Calculation of the aortic arch angles from three-dimensional reconstructions of computed tomography scans: Comparison between an automated program and visual assessment
Artículo
Material complementario disponible Artículo CONICET Digital
Calculation of the aortic arch angles from three-dimensional reconstructions of computed tomography scans: Comparison between an automated program and visual assessment
Gaudric, Julien et al · Pergamon-Elsevier Science Ltd · 2019 · ISSN 0010-4825
Background: The curvature of the aortic arch is associated with the risk of endoleak formation after thoracic endovascular aortic repair (TEVAR). However, the adequate assessment of the angles of the aorta continues to r...
Idioma eng
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Computer-Aided Drug Discovery and Design: Recent Advances and Future Prospects
Libro electrónico
Acceso abierto Libro electrónico CONICET Digital
Computer-Aided Drug Discovery and Design: Recent Advances and Future Prospects
Talevi, Alan · Humana Press · 2024 · ISSN 0716-3440
Computer-aided drug discovery and design involve the use of information technologies to identify and develop, on a rational ground, chemical compounds that align a set of desired physicochemical and biological properties...
Idioma eng
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First WHO International Reference Panel containing hepatitis B virus genotypes A-G for assays of the viral DNA
Artículo
Acceso abierto Artículo CONICET Digital
First WHO International Reference Panel containing hepatitis B virus genotypes A-G for assays of the viral DNA
Chudy, M. et al · Elsevier Science · 2012 · ISSN 1386-6532
Background: WHO International Standards (IS) are provided for the calibration and validation of diagnostic and screening assays, e.g. for hepatitis B virus (HBV). HBV forms numerous subgenotypes and the current IS for HB...
Idioma eng
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Greenness and whiteness evaluation of HPTLC methodology for simultaneous assay of aceclofenac and paracetamol in fixed-dose combination tablet dosage forms
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Greenness and whiteness evaluation of HPTLC methodology for simultaneous assay of aceclofenac and paracetamol in fixed-dose combination tablet dosage forms
Aljarba Tariq M. et al · De Gruyter · 2026 · ISSN 2191-9550
This study establishes and validates a sustainable reverse-phase “high-performance thin-layer chromatography (HPTLC)” methodology for the concurrent assay of aceclofenac (ACC) and paracetamol (PCT) in their fixed-dos...
LCC TENDOkNoZW1pc3RyeQ~~Idioma eng
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Large-scale molecular analysis of hereditary hearing loss genes in argentinean deaf patients: lookingfora needle in a haystack
Revista
Acceso abierto Revista CONICET Digital
Large-scale molecular analysis of hereditary hearing loss genes in argentinean deaf patients: lookingfora needle in a haystack
Buonfiglio, Paula Inés et al · Springer · 2019 · ISSN 1018-4813
Hereditary Hearing Loss (HHL) is a common trait affecting 1 in 2000 new born children. The presence of over 100 different genes involved in HHL, lead us to go on board with Whole Exome Sequencing (WES) in order to search...
Idioma eng
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Verification of LNG Dispersion Simulation Using FDS Based on Burro3 Experimental Results
Artículo
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Verification of LNG Dispersion Simulation Using FDS Based on Burro3 Experimental Results
Seong Min Seo et al · The Korean Society of Ocean Engineers · 2026 · ISSN 1225-0767
Prior validation against well-documented benchmark experiments is essential for establishing a reliable computational foundation for liquefied natural gas (LNG) vapor dispersion simulations in safety assessments and haza...
LCC LCC:Ocean engineeringIdioma eng
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16S rRNA gene sequencing reveals distinct intratumoral bacterial microbiome signatures between CT indeterminate benign and early-stage malignant pulmonary lesions
Artículo
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16S rRNA gene sequencing reveals distinct intratumoral bacterial microbiome signatures between CT indeterminate benign and early-stage malignant pulmonary lesions
Yanfei Liu et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Existing research suggested that the intratumoral microbiome participates in the progression and metastasis of lung cancer. However, its role in distinguishing benign from early-stage malignant pulmon...
LCC LCC:MedicineIdioma eng
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A 2.5D multichannel deep learning model using contrast-enhanced ultrasound for predicting malignancy in breast nodules: a two-center study
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A 2.5D multichannel deep learning model using contrast-enhanced ultrasound for predicting malignancy in breast nodules: a two-center study
Jianfeng Xie et al · Frontiers Media S.A · 2026 · ISSN 1664-042X
ObjectiveTo evaluate a novel multichannel deep learning (DL) model using contrast-enhanced ultrasound (CEUS) data with multiple regions of interest (ROIs) and time-intensity curve (TIC)-derived key frames for predicting ...
LCC TENDOlBoeXNpb2xvZ3k~Idioma eng
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A combined model of BCVA, TRAb, and NLR predicts response to intravenous methylprednisolone in dysthyroid optic neuropathy
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A combined model of BCVA, TRAb, and NLR predicts response to intravenous methylprednisolone in dysthyroid optic neuropathy
Shu Liu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
BackgroundHigh-dose intravenous methylprednisolone (HD-IVMP) is the first-line treatment for dysthyroid optic neuropathy (DON). However, a significant proportion of patients exhibit a poor response, risking irreversible ...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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A dual-modal machine learning framework integrating red blood indices and smartphone-captured microscopic images for β-thalassemia screening
Artículo
Material complementario disponible Artículo DOAJ
A dual-modal machine learning framework integrating red blood indices and smartphone-captured microscopic images for β-thalassemia screening
C. R. Wijesinghe et al · BMC · 2026 · ISSN 1472-6947
Abstract Background Thalassemia is the most prevalent single-gene disorder in Sri Lanka, imposing a significant socioeconomic and healthcare burden. Early carrier detection is essential for genetic counselling and the pr...
LCC TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng
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A nomogram for predicting the risk of bronchopulmonary dysplasia in preterm infants: a prospective multicenter study
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A nomogram for predicting the risk of bronchopulmonary dysplasia in preterm infants: a prospective multicenter study
Yanping Guo et al · Frontiers Media S.A · 2026 · ISSN 2296-2360
BackgroundBronchopulmonary dysplasia (BPD) is a common and serious complication in very preterm infants, with potential long-term adverse effects. This study aimed to analyze the perinatal and postnatal risk factors for ...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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A preoperative nomogram for predicting 2-year postoperative recurrence after percutaneous transforaminal endoscopic decompression in degenerative lumbar spinal stenosis
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A preoperative nomogram for predicting 2-year postoperative recurrence after percutaneous transforaminal endoscopic decompression in degenerative lumbar spinal stenosis
Xinyi Luo et al · Frontiers Media S.A · 2026 · ISSN 2673-8740
Background and objectivesPostoperative recurrence after percutaneous transforaminal endoscopic decompression (PTED) for degenerative lumbar spinal stenosis (DLSS) remains a clinically relevant challenge, complicating pre...
LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~Idioma eng
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Association of accelerated biological aging with obstructive sleep apnea symptoms and identification of a candidate biomarker gene signature
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Association of accelerated biological aging with obstructive sleep apnea symptoms and identification of a candidate biomarker gene signature
Yixuan Wang et al · BMC · 2026 · ISSN 1868-7083
Abstract Background Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder that is linked to cardiovascular, metabolic, and neurocognitive complications. However, its diagnosis relies on polysomnograp...
LCC LCC:Medicine; LCC:GeneticsIdioma eng
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Bayesian Approach for Analyzing Computer Models using Gaussian Process Models.
Artículo
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Bayesian Approach for Analyzing Computer Models using Gaussian Process Models.
hasan Saeid et al · University of Mosul, College of Education for Pure Science · 2021 · ISSN 1812-125X
Mathematical models, usually implemented in computer programs known as computer models, are widely used in all areas of science and technology to represent complex systems in the real world. However, computer models are ...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma eng
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Bile acid metabolomics reveals distinct immunometabolic niches and enables accurate diagnosis of AQP4-IgG–seronegative NMOSD
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Bile acid metabolomics reveals distinct immunometabolic niches and enables accurate diagnosis of AQP4-IgG–seronegative NMOSD
Zixin Chen et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Background and ObjectiveDifferentiating neuromyelitis optica spectrum disorder (NMOSD) from multiple sclerosis (MS) is clinically difficult, especially when patients are seronegative for anti–aquaporin-4 immunoglobulin...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Cluster habitat-based diffusion MRI radiomics for differentiation of glioblastoma from solitary brain metastasis
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Cluster habitat-based diffusion MRI radiomics for differentiation of glioblastoma from solitary brain metastasis
Wenzheng Luo et al · SpringerOpen · 2026 · ISSN 2509-9280
Abstract Objective Given the distinct intratumoral heterogeneity of glioblastoma (GB) and solitary brain metastasis (SBM), habitat-based radiomics derived from neurite orientation dispersion and density imaging (NODDI) m...
LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~Idioma eng
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