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Here, we identify a novel signaling pathway in which Rnd3 regulates the metastatic potential of lung cancer cells. Understanding this pathway could be leveraged to target metastatic disease. Rnd3 regulates cellular proce...

Este estudio se desprende de una investigación más amplia denominada "La co-construcción de significados educativos en una comunidad del aprendizaje", que plantea la transformación de la cultura del aula al tiempo qu...

Abstract Introduction We aimed to evaluate the safety, efficacy and surgical outcomes of combined laparoscopic/vaginal prolapse repair by two surgeons. Material and Methods A retrospective chart review of all patient...

Abstract Precipitation is expected to increase in a warmer global climate, yet how sensitive precipitation is to warming depends on poorly constrained cloud radiative processes. Clouds respond to surface warming in ways ...

Abstract Background Many individuals with bipolar disorder have decreased levels of cognitive functioning even when in a euthymic mood state. Persons with bipolar disorder are usually treated with psychotropic agents, bu...

To assess the feasibility of methods and estimate the potential effect of interrupting sedentary behaviour, with intermittent or continuous physical activity breaks, on cognitive performance in young people with Cerebral...

Abstract Bird wings exhibit a broad degree of functional and shape variation, though the exact nature of the form-function relationship is uncertain. Recent analysis suggests that functional variability is explained by l...

Abstract Background Borderline personality disorder (BPD) is a significant cause of morbidity with no approved pharmacological treatment. We assessed treatment trajectories of patients with BPD in real-world clinical pra...

Objectives: To describe the experiences of U.S. tuberculosis (TB) program officials participating in contact investigations after TB exposures on aircraft in order to 1) characterize barriers to participation and 2) bett...

Abstract Hemangioma is a benign neoplasm that may affect the vulva, and it can cause functional or emotional disability. This article reports the case of a 52-year-old female patient with a history of a genital ulcer for...

Abstract Dietary load and composition are known contributors that accelerate cyst growth in polycystic kidney disease (PKD). High protein intake, which increases amino acid burden in the kidneys, is one such factor. Desp...

Colonial seabirds are central place foragers and likely to be subject to substantial competition for resources. Mechanisms proposed for reducing intra-specific competition include differential inter-sex area use mediated...

mothur aims to be a comprehensive software package that allows users to use a single piece of software to analyze community sequence data. It builds upon previous tools to provide a flexible and powerful software package...

La relación entre la literatura, el escritor y la vida, más específicamente, la manera en que se comprende la vida en el marco de esta relación constituye una pieza clave para la definición del peculiar modo de leer...