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The vertebrate Hedgehog (Hh) pathway has essential functions during development and tissue homeostasis in normal physiology, and its dysregulation is a common theme in cancer. The Hh ligands (Sonic Hh, Indian Hh, and Des...

El siguiente artículo presenta un análisis de las principales experiencias y trabajos de campo realizados por parte del equipo de investigación de la Universidad Nacional de Misiones (UNaM) de la República Argentina ...

There is unequivocal evidence that alpha-synuclein plays a pivotal pathophysiological role in neurodegenerative diseases, and in particular in synucleinopathies. These disorders present with a variable extent of cognitiv...

Abstract Background Ankle arthrodesis is an established procedure for end-stage ankle osteoarthritis. Besides the known limited functionality, gait and foot arch changes are accompanying pathologies, which are little inv...

Adoptive therapy with CD19 chimeric antigen receptor (CAR) T cells is effective against B-cell malignancies; however, T-cell activation rapidly declines, increasing the risk of early leukemia relapses. To augment CD19 CA...

Abstract The primary goal of fluid therapy is to optimize cardiac output in preload-dependent patients. However, all types of fluid solutions can have side effects. Oral water intake regulates fluid absorption, leading t...

We report for the first time the direct growth of molybdenum disulfide (MoS2) monolayers on nanostructured silicon-on-insulator waveguides. Our results indicate the possibility of utilizing the Chemical Vapour Deposition...

Abstract Background The BladderScan Prime Plus (BPP; Verathon, Bothell, Washington) is an application‐specific, three‐dimensional ultrasound device used for human, point‐of‐care volumetry of the urinary bladder. ...

Numerous studies have documented subtle but consistent sex differences in self-reports and observer-ratings of five-factor personality traits, and such effects were found to show welldefined developmental trajectories an...

IntroductionSinonasal aspergillosis (SNA) is a frequent cause of chronic nasal discharge, predominantly caused by Aspergillus fumigatus. The infection is typically confined to the nasal cavity and/or frontal sinuses, cha...

Next generation risk assessment (NGRA) demands a fundamental transformation in how toxicological test methods are validated. Traditional validation approaches, designed for animal tests and mainly for simple in vitro met...

We demonstrate a grazing-incidence X-ray platform that simultaneously records time-resolved grazing-incidence small-angle X-ray scattering (GISAXS) and grazing-incidence X-ray diffraction (GID) from a femtosecond-laser-i...

Abstract Background Traditionally, 6‐month courses of prednisolone are used to treat steroid‐responsive meningitis‐arteritis (SRMA), but this medication is associated with adverse effects that can lead to poor qual...

Introduction Early open fracture management aims to minimise the risk of complications. For the most severe open fracture wounds, multiple irrigation and debridement surgeries are required to overcome severe wound contam...

BackgroundIschemic stroke is a leading cause of global morbidity and mortality, with seasonal variations potentially influencing both outcomes. While previous studies have suggested a pronounced association of the cold m...

The first public product of the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) is its Conceptual Framework. This conceptual and analytical tool, presented here in detail, will underpin all IPBE...

Abstract Cloaking is a method of making obstacles undetectable. Here we cloak unit cells of a magnetic pattern squeezed into an otherwise periodic pattern from a magnetically driven colloidal flow. We apply a time-period...

Fil: Thomasz, Esteban Otto. Universidad de Buenos Aires. Facultad de Ciencias Económicas. Instituto de Investigaciones en Administración, Contabilidad y Matemática. Programa de Investigación en valuación de la vulne...

Fil: Scheetz, Thomas. Universidad Nacional de Quilmes. Centro de Estudios e Investigaciones; Argentina. Fil: Scheetz, Thomas. Universidad Nacional de Quilmes. Departamento de Ciencias Sociales; Argentina. Existen dos man...

Fil: Thomas, Hernán. Universidad Nacional de Quilmes. Instituto de Estudios Sociales de la Ciencia y la Tecnología; Argentina. Fil: Lalouf, Alberto. Universidad Nacional de Quilmes. Instituto de Estudios Sociales de l...

Fil: Pérez Gianmarco, Thomas Ignacio. Universidad de Buenos Aires. Facultad de Agronomía. Argentina. En el desarrollo del cultivo de trigo se suceden etapas (vegetativa, reproductiva temprana, y tardía) y procesos (di...

Fil: Thomas, Hernán. Universidad Estadual de Campinas. Departamento de Política Científica y Tecnológica; Brasil. Es poco común encontrar estudios sobre temas tecnológicos en la reflexión académica latinoamerican...

Fil: Thomas, Hernán. Universidad Nacional de Quimes. Instituto de Estudios sobre la Ciencia y la Tecnología; Argentina. Fil: Thomas, Hernán. Universidad Nacional de Lanús; Argentina. Fil: Juárez, Paula. Universidad ...