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We describe a model-based clustering method for using multilocus genotype data to infer population structure and assign individuals to populations. We assume a model in which there are K populations (where K may be unkno...

Materias / palabras clave: Biology; Gene; DNA microarray; Gene expression profiling; Gene expression; Oxidative phosphorylation; Genetics; Regulation of gene expression; Computational biology; Biochemistry

Materias / palabras clave: Population stratification; Spurious relationship; Biology; Principal component analysis; Allele frequency; Genetic association; Genome-wide association study; Population; Evolutionary biology; Computational biology; Geno...

Current clinical practice is organized according to tissue or organ of origin of tumors. Now, The Cancer Genome Atlas (TCGA) Research Network has started to identify genomic and other molecular commonalities among a doze...

In this paper we report exploratory analyses of high-density oligonucleotide array data from the Affymetrix GeneChip system with the objective of improving upon currently used measures of gene expression. Our analyses ma...

There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We describe a joint GWA study (using the Affymetrix ...

Our interest is to define evolutionary algorithms to solve Constraint Satisfaction Problems (CSP), which indlude benefits of taditional resolution methods of CSPs as well as inherent characteristics of these kind of prob...

Fil: Mandile, Marcelo Gastón. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina El plan de trabajo pensado para esta tesis involucró como primer objetivo la vigilancia epidemiológica y ...

Fil: Boccardo, Noelia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina En el marco de este trabajo de tesis doctoral, s...

Fil: Abelleyro, Miguel Martín. Instituto de Medicina Experimental; Argentina Después de la revolución científica y tecnológica que atravesó la genética médica en los últimos años, el gran desafío que hoy enfre...

Este artículo analiza algunas ideas, imágenes y creencias relacionadas con las nuevas "ciencias de la vida", y cuestiona su influencia en las redefiniciones de la condición humana, la salud y la enfermedad que están ...

The fine detail provided by sequencing-based transcriptome surveys suggests that RNA-seq is likely to become the platform of choice for interrogating steady state RNA. In order to discover biologically important changes ...

A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components, i.e., the gene diversities within and between subpopulations. This method is applicable t...

We describe Hi-C, a method that probes the three-dimensional architecture of whole genomes by coupling proximity-based ligation with massively parallel sequencing. We constructed spatial proximity maps of the human genom...

Materias / palabras clave: Biology; Molecular genetics; Gene; Genetics; Molecular marker; Beta-glucuronidase; Library science; Gene expression; Computer science

A measure of genetic distance (D) based on the identity of genes between populations is formulated. It is defined as D = -logeI, where I is the normalized identity of genes between two populations. This genetic distance ...

A 16S rRNA gene database (http://greengenes.lbl.gov) addresses limitations of public repositories by providing chimera screening, standard alignment, and taxonomic classification using multiple published taxonomies. It w...

A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this model are presented for estimating the number of nucleotide substitutions between two popula...

Materias / palabras clave: Plasmid; Transformation (genetics); Escherichia coli; Plasmid preparation; Biology; Incubation; Dithiothreitol; T-DNA Binary system; DNA; Transformation efficiency; Chemistry; Genetics

The Ensembl Variant Effect Predictor is a powerful toolset for the analysis, annotation, and prioritization of genomic variants in coding and non-coding regions. It provides access to an extensive collection of genomic a...

A partir de registros de 420 estudiantes se analizaron las siguientes variables: año de ingreso (AI), año de nacimiento (AN), número de materias cursadas (nca) y número de exámenes finales de primer año aprobados (...

BACKGROUND: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method for describing the correlation patterns a...

Materias / palabras clave: plant genetics and breeding, animal genetics and breeding, genetics and breeding of microorganisms, human genetics, medical genetics, bioengineering; Science: Biology (General): Genetics

Materias / palabras clave: molecular biology, genomics, cellular biology, genetics, plant genetics; Science: Biology (General): Genetics; Science: Biology (General): Reproduction