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Throughout history, our capacity to shed tears has attracted the attention of poets, writers, philosophers, and scholars. Moreover, humans' fascination with tears is evident in the significant roles they played in legend...

Abstract The heart-brain axis is a significant contributor to morbidity and mortality following ischemic injury. Pathological and psychological changes in the heart can lead to anxiety, cognitive impairment, and brain in...

Abstract Certain human mutations in the mitochondrial aldehyde dehydrogenase 4A1 (ALDH4A1) lead to a severe, paediatric form of epilepsy and developmental abnormalities, yet the precise molecular mechanism leading to the...

El concepto de reserva cerebral y cognitiva (RCC) fue establecido con el objeto de explicar por qué y cómo ciertos individuos, pese a estar afectados por una patología cerebral, no expresan las alteraciones cognitivas...

Background and Aim: Cerebral ischemia is a major neurological condition that contributes significantly to global morbidity and mortality. It occurs due to reduced blood supply to the brain, leading to neuronal injury and...

The main concepts presented in this review are that sleep is not a function but a state diverse from the waking one. A lot of physiologic functions are carried out during sleep, cardiovascular, respiratory, endocrine, se...

Abstract In recent times, both in vitro and in vivo studies have demonstrated toxicological and pathological evidence of microplastic exposure in neurological dysfunction and diseases. The mechanistic linkage of micropla...

Paraneoplastic syndromes (PNS) are triggered by an altered immune system response to a neoplasm. The symptoms of PNS usually precede malignancy making its diagnosis difficult. They are rarely associated with breast cance...

We performed a single-center retrospective analysis of chronic granulomatous disease (CGD) autopsy reports to better understand causes of death, end-organ damage, and disease pathophysiology. Forty-four autopsies of CGD ...

Encephalitis in immunocompromised individuals presents a unique diagnostic and treatment challenge due to the interplay between infection and immune dysregulation.A 48-year-old male with a history of recurrent sinusitis ...

A baseline or control state is fundamental to the understanding of most complex systems. Defining a baseline state in the human brain, arguably our most complex system, poses a particular challenge. Many suspect that lef...

Materias / palabras clave: Modularity (biology); Complex network; Magnetoencephalography; Computer science; Cognitive science; Connectomics; Diffusion MRI; Graph theory; Human brain; Network science; Neuroscience; Neuroimaging

An automated method for segmenting magnetic resonance head images into brain and non-brain has been developed. It is very robust and accurate and has been tested on thousands of data sets from a wide variety of scanners ...

Magnetic Resonance Imaging is one of the most important medical imaging techniques for the investigating diseases of the human brain. A novel method for automatic segmentation Magnetic resonance brain image framework is ...

Glioblastoma is one of the most malignant brain tumors. Current treatments for glioblastoma usually make poor responses, and novel treatment strategies are extremely imperative. Cytochalasin E was reported to inhibit ang...

"Error-related potential (ErrP) are a particular type of Event-Related Potential (ERP) elicited by a person attending a recognizable error. These Electroencephalographic (EEG) signals can be used to train a gaming agent ...

The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data collected on approximately 500,000 individuals from across the United Kingdom, aged between 40 and 69 at recruitment. The open re...

Fil: Albite, Romina Débora. Hospital Italiano. Instituto de Ciencias Básicas y Medicina Experimental; Argentina. Actualmente definimos estrés a cualquier condición que perturbe el equilibrio del organismo (homeostasi...

El documento tiene como pretensión, en un primer momento, establecer líneas de diferenciación entre la ciencia clásica y la ciencia contemporánea, develando las lógicas convencionales de la razón positiva y sus di...

Scientists working with large volumes of high-dimensional data, such as global climate patterns, stellar spectra, or human gene distributions, regularly confront the problem of dimensionality reduction: finding meaningfu...

Little has been done in the study of these intriguing questions, and I do not wish to give the impression that any extensive set of ideas exists that could be called a "theory." What is quite surprising, as far as the hi...

Bartlett viewed thinking as a high level skill exhibiting ballistic properties that he called its “point of no return”. This paper explores one aspect of cognition through the use of a simple model task in which huma...

Behavioral and molecular methods were used to study and determine whether there is a link between depression that may be a factor in drug/alcohol addiction, and the endocannabinoid hypothesis of substance abuse. Depressi...