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Introduction Mucosal melanoma (MM) carries a high risk of postoperative relapse and poorer survival than cutaneous disease. Prospective data from China support adjuvant temozolomide–cisplatin (TMZ/DDP) in resected MM, ...

Hand eczema is a common skin disorder with significant functional and economic impacts. Conventional therapy options, such as topical corticosteroids, calcineurin inhibitors, phototherapy and systemic immunosuppressants,...

Severe gingival inflammation, which is uncommon in pediatric patients, often indicates underlying systemic conditions. Leukemia, autoimmune diseases, and allergic symptoms can cause gingivitis owing to systemic inflammat...

IntroductionChronic spontaneous urticaria (CSU) is a clinical diagnosis managed according to American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma & Immunology (ACAAI) guide...

Objective This study aimed to describe the clinical and neuroimaging characteristics and 120-day outcomes in neuropsychiatric systemic lupus erythematosus patients. Methods This prospective study involved 32 patients wit...

Abstract Background Understanding of equine herpesvirus‐1 (EHV‐1) myeloencephalopathy (EHM) is complicated by disparities among studies. Objective Compare clinical findings and outcome in horses involved in 2 recent ...

En este artículo exploramos, desde una perspectiva sistémico-funcional, el papel que desempeñan dos subgrupos de procesos verbales, los "procesos de decir + cualidad" y los "proceso de juicio", en la codificación de ...

Background: Osteoporosis has long been considered a disorder confined to bone tissue. Growing evidence now highlights its systemic origins, governed by intricate communication between multiple organs. The multi-organ-bon...

Abstract Background Erythrodermic psoriasis (EP) is a severe, systemic inflammatory dermatosis. While kidney involvement is rare, the massive cytokine release associated with EP can induce systemic complications. We repo...

The article argues for the urgency of research on an individual’s intellectual and creative giftedness and emphasizes the theoretical, psychological, pedagogic, and socio-economic significance of the problem. It is cla...

ABSTRACT Background and Aims To evaluate the transition of Carbohydrate antigen 125 (CA‐125) from an ovarian tumor marker to a versatile indicator of systemic congestion and fluid overload. Methods A literature review ...

Acute hypoxia is a significant physiological danger during high-altitude flying and military aircraft missions. The human brain requires a constant supply of oxygen to function properly, and is susceptible to settings wi...

Abstract Acquired immunity in plants, including systemic acquired resistance (SAR) and induced systemic resistance (ISR), plays a central role in protecting crops against a wide spectrum of pathogens and pests, ranging f...

Abstract Background Systemic hypertension (SH) is a potential complication of acute kidney injury (AKI) in dogs. Objective To describe the prevalence of SH and hypertensive retinopathy in dogs with AKI, to investigate th...

The current stage of reforming the Ukrainian national school is characterized by a complication of the сontent of education, an increase in the amount of information and a reduction in the time allotted for its learning...

Background: Applications and admission processes across the globe have been unified using central application systems (CAS). However, the primary CAS in South Africa (SA), including the Central Applications Office and t...

Abstract Background Systemic antibiotic administration requires repeated dosing to maintain therapeutic plasma concentrations. Controlled drug delivery systems reduce the need for continuous systemic antibiotic use by en...

ObjectiveThe present Bayesian network meta-analysis (NMA) aims to evaluate and compare the efficacy of aerobic training (AT), resistance training (RT), high-intensity interval training (HIIT), and combined training (CT) ...

Both uremia and bioincompatibility of hemodialysis result in a chronic systemic inflammatory syndrome. There is evidence for the activation of monocytes and subsequent release of several proinflammatory cytokines in urem...

The article provides a brief overview of the state of international political relations, states the transformation of the subjectivity of global processes and draws a conclusion about the crisis phenomena of modern globa...

Purpose: To assess the impact of non-surgical periodontal treatment (NSPT) on the oxidative and endoplasmic reticulum (ER) stress response of leukocytes, and to examine whether obesity modulates the biological response t...

OBJECTIVE: Ultrafiltration (UF) failure is a frequent complication of peritoneal dialysis peritonitis. Octreotide (OCT) has antiproliferative effects on many cells. The present study aimed to investigate the effect of OC...

Bullous pemphigoid is an autoimmune blistering disease that very rarely affects children. Clinical differences in locations of skin lesions led to the distinction of infantile versus childhood pemphigoid. Mucous membrane...

The early postoperative period in infants following the correction of congenital heart defects is often accompanied by hemodynamic lability, systemic stress, and an acute-phase response, which may lead to transient organ...