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Materias / palabras clave: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system

Abstract Background/Objective Asthma medication adherence, measured by the asthma medication ratio (AMR), has been shown to be a reliable predictor of exacerbations among children with asthma. We developed a Markov model...

Abstract The introduction of biologicals interfering with the interleukin-5 (IL-5) pathway has revolutionized the treatment of severe eosinophilic asthma (SEA), rendering remission an achievable goal even in patients wit...

Abstract Asthma is a chronic inflammatory airway disease with a rising global prevalence and impact on quality of life. Conventional therapeutics such as corticosteroids and β2-agonists are associated with various long-...

Abstract Background Air pollution particles exacerbate allergic asthma and can enhance inflammatory responses to allergen exposure, but the cellular mechanisms involved remain incompletely defined. We examined how diesel...

Abstract Background Periodontal disease exhibits bidirectional associations with autoimmune diseases; however, comprehensive histological, radiographic, and correlational differences in periodontal tissues between patien...

Abstract Background Migraine is a very common chronic neurological disorder associated with severe disability and significant social burden worldwide. Beyond recurrent headache attacks, increasing evidence indicates that...

Abstract Hereditary angioedema (HAE) is a rare, potentially life-threatening genetic disorder characterized by recurrent subcutaneous and/or submucosal edema, most commonly caused by deficiency in C1-esterase inhibitor. ...

Abstract This update to the 2019 Canadian Hereditary Angioedema (HAE) Guideline broadens its focus to include the management of patients with HAE worldwide, building on its established international framework. It has bee...