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14 resultados encontrados.

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High-gamma tACS may regulate brain network connectivity to alleviate symptoms in female adolescent non-suicidal self-injury: a preliminary TMS-EEG pilot study
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High-gamma tACS may regulate brain network connectivity to alleviate symptoms in female adolescent non-suicidal self-injury: a preliminary TMS-EEG pilot study
Wensi Hao et al · BMC · 2026 · ISSN 1471-244X
Abstract Objectives To explore the efficacy and potential neurophysiological mechanisms of 77.5 Hz transcranial alternating current stimulation (tACS) in the treatment of female adolescent non-suicidal self-injury (NSSI...
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
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Cortical functional hierarchy disruption following subcortical stroke
Artículo
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Cortical functional hierarchy disruption following subcortical stroke
Ke Wu et al · BMC · 2026 · ISSN 1741-7015
Abstract Background Subcortical structures are pivotal for cortico-subcortical communication, yet are highly vulnerable to stroke. Damage to these structures can produce widespread cortical dysfunction, but how subcortic...
LCC LCC:MedicineIdioma eng
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N-terminally acetylated Met11-Tau: a new pathological truncated Tau species with functional relevance in Alzheimer's disease
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N-terminally acetylated Met11-Tau: a new pathological truncated Tau species with functional relevance in Alzheimer's disease
Sarah Guedjdal et al · BMC · 2026 · ISSN 2047-9158
Abstract Background Tauopathies are a group of neurodegenerative diseases, including Alzheimer’s disease (AD), characterized by progressive accumulation of pathological Tau proteins. Among the diverse Tau species, trun...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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The obesity-brain axis: a comprehensive review of neurological complications and therapeutic interventions in metabolic syndrome
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The obesity-brain axis: a comprehensive review of neurological complications and therapeutic interventions in metabolic syndrome
Amin Roshdy Soliman et al · BMC · 2026 · ISSN 1758-5996
Abstract Background Obesity has emerged as a major global health issue, affecting multiple organ systems. Within the central nervous system obesity causes a series of disruptions that can significantly affect neurologica...
LCC LCC:Nutritional diseases. Deficiency diseasesIdioma eng
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Effects of transcranial direct current stimulation (tDCS) on cognition in older adults with mild cognitive impairment: a study protocol for a randomized controlled trial
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Effects of transcranial direct current stimulation (tDCS) on cognition in older adults with mild cognitive impairment: a study protocol for a randomized controlled trial
Michael Chih Chien Kuo et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Mild cognitive impairment (MCI) is an intermediate stage between normal cognitive aging and dementia. People with MCI have a higher risk of developing dementia than normal healthy people. Improving th...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Single-cell RNA sequencing uncovers neutrophil clusters associated with autoimmune neuroinflammation
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Single-cell RNA sequencing uncovers neutrophil clusters associated with autoimmune neuroinflammation
Yong Wang et al · BMC · 2026 · ISSN 1742-2094
Abstract Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS) characterized by multifocal inflammation and axonal degeneration, driven by innate and adaptive immune cells. Th...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Symptom clusters in ME/CFS reflect distinct neuroimmune and autonomic pathophysiological mechanisms: a translational model
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Symptom clusters in ME/CFS reflect distinct neuroimmune and autonomic pathophysiological mechanisms: a translational model
Lotte Habermann-Horstmeier et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disease characterized by heterogeneous symptom patterns. Previous work suggested that specific symptoms tend t...
LCC LCC:MedicineIdioma eng
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The role of stem cells and their engineering strategies in the repair of nerve damage in intracerebral hemorrhage
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The role of stem cells and their engineering strategies in the repair of nerve damage in intracerebral hemorrhage
Liangzhe Wei et al · BMC · 2026 · ISSN 2045-3701
Abstract Intracerebral hemorrhage (ICH) is a devastating neurological condition with high mortality and morbidity. Despite advancements in medical and surgical treatments, the long-term prognosis of ICH remains poor. Ste...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:Biology (General); TENDOkJpb2NoZW1pc3RyeQ~~Idioma eng
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A ligand-mimetic anti-TREM2 agonist antibody elevates soluble TREM2 and ameliorates pathology in mouse models of Alzheimer’s disease and multiple sclerosis
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A ligand-mimetic anti-TREM2 agonist antibody elevates soluble TREM2 and ameliorates pathology in mouse models of Alzheimer’s disease and multiple sclerosis
Buxin Chen et al · BMC · 2026 · ISSN 1742-2094
Abstract Background Triggering receptor expressed on myeloid cell-2 (TREM2) signaling promotes disease-associated microglia (DAM) and phagocytosis in neurodegenerative diseases. Traditional anti-TREM2 agonist antibodies ...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Cerebrovascular claudin-5 isoform expression correlates with worsened stroke outcomes following thromboembolic stroke
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Cerebrovascular claudin-5 isoform expression correlates with worsened stroke outcomes following thromboembolic stroke
Trevor S. Wendt et al · BMC · 2026 · ISSN 2045-8118
Abstract Background and purpose Claudin-5 plays a crucial role in maintaining blood-brain barrier (BBB) integrity through endothelial tight junction formation. Alternative splicing of claudin-5 within the microvascular e...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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DNA methylation signatures of Life’s Essential 8 and their implications for dementia
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DNA methylation signatures of Life’s Essential 8 and their implications for dementia
David Lukacsovich et al · BMC · 2025 · ISSN 1758-9193
Abstract Background As dementia cases continue to rise, effective prevention strategies are urgently needed. However, objective biomarkers that directly reflect lifestyle factors remain limited. Life’s Essential 8 (LE8...
LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurology. Diseases of the nervous systemIdioma eng
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Endoplasmic reticulum stress inhibitor 4-PBA alleviates immune damage in mice with enteroviral encephalitis by inhibiting ferroptosis
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Endoplasmic reticulum stress inhibitor 4-PBA alleviates immune damage in mice with enteroviral encephalitis by inhibiting ferroptosis
Sijie He et al · BMC · 2026 · ISSN 1743-422X
Abstract Introduction Enterovirus A71 (EV71)–associated encephalitis lacks targeted neuroprotective therapy. Experimental data implicate endoplasmic reticulum (ER) stress and ferroptosis in neuronal injury. We tested w...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Inflammatory signaling differentially changes chromatin accessibility and gene expression of the PD- associated kinase LRRK2 between human and mice
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Inflammatory signaling differentially changes chromatin accessibility and gene expression of the PD- associated kinase LRRK2 between human and mice
Alexandra Beilina et al · BMC · 2026 · ISSN 1750-1326
Abstract The genomic locus that encodes the Leucine-rich repeat kinase 2 (LRRK2) gene is highly pleiotropic and associated with Parkinson’s disease (PD). Coding variants associated with risk of PD act as gain of functi...
LCC LCC:Neurology. Diseases of the nervous system; TENDOkdlcmlhdHJpY3M~Idioma eng
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Severe pulmonary and cerebral fat embolism with sudden cardiac and respiratory arrest after cesarean section: a case report
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Severe pulmonary and cerebral fat embolism with sudden cardiac and respiratory arrest after cesarean section: a case report
Yicong Chen et al · BMC · 2026 · ISSN 1471-2377
Abstract Background Fat embolism syndrome (FES) is commonly associated with orthopedic trauma, but the diagnosis is challenging with an uncommon nontraumatic cause. It is difficult to discriminate from thrombo-embolism i...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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